Impact of Low-Frequency Pulsed Magnetic Fields on Defensin and CRP Concentrations in Patients with Painful Diabetic Polyneuropathy and in Healthy Subjects

Aim. The aim was to assess whether magnetic field influences defensin and CRP concentrations in patients with diabetic polyneuropathy and in healthy subjects. Methods. 61 diabetic patients were randomly divided into 2 groups: study group-32 patients exposed to low-frequency magnetic field; and contr...

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Bibliographic Details
Published in:	Electromagnetic biology and medicine Vol. 29; no. 1-l2; pp. 19 - 25
Main Authors:	Szymborska-Kajanek, Aleksandra, Strzelczyk, Joanna Katarzyna, Karasek, Dariusz, Rawwash, Hend Anna, Biniszkiewicz, Tomasz, Cie lar, Grzegorz, Hajdrowska, Bogumi a, Siero -Sto tny, Karolina, Siero, Aleksander, Wiczkowski, Andrzej, Grzeszczak, W adys aw, Strojek, Krzysztof
Format:	Journal Article
Language:	English
Published:	England Informa UK Ltd 01-01-2010 Taylor & Francis
Subjects:	Adult C-Reactive Protein - metabolism Case-Control Studies CRP Defensin Defensins - metabolism Diabetes Diabetic Neuropathies - metabolism Electromagnetic Fields Female Health Humans Magnetic field Male Middle Aged
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Summary:	Aim. The aim was to assess whether magnetic field influences defensin and CRP concentrations in patients with diabetic polyneuropathy and in healthy subjects. Methods. 61 diabetic patients were randomly divided into 2 groups: study group-32 patients exposed to low-frequency magnetic field; and control group-29 patients with sham exposure. Additionally, 20 healthy subjects exposed to low-frequency magnetic field. Exposures were performed during 3 weeks, 5 days in a week. Defensin and CRP concentrations were measured at baseline, after 3 weeks and at the end of the study. Results. There were no significant changes in defensin concentration in patients with diabetes in both the real and sham exposure group. We observed increased concentration of defensin in healthy subjects in week 5 vs. baseline value (P<0.02). Conclusions. Magnetic field has no impact on defensin concentration in diabetic patients but has positive influence on this parameter in healthy subjects.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-News-1 ObjectType-Feature-3 content type line 23
ISSN:	1536-8378 1536-8386
DOI:	10.3109/15368371003635376