Search Results - "Haj‐Dahmane, Samir"

Mechanisms of endocannabinoid transport in the brain by Kaczocha, Martin, Haj‐Dahmane, Samir

“…The endocannabinoids 2‐arachidonoylglycerol (2‐AG) and anandamide are among the best studied lipid messengers in the brain. By activating cannabinoid receptors…”
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Prenatal Ethanol Exposure and Postnatal Environmental Intervention Alter Dopaminergic Neuron and Microglia Morphology in the Ventral Tegmental Area During Adulthood by Aghaie, Claudia I., Hausknecht, Kathryn A., Wang, Ruixiang, Dezfuli, Parisa Halaji, Haj‐Dahmane, Samir, Kane, Cynthia J. M., Sigurdson, Wade J., Shen, Roh‐Yu

“…Background Prenatal ethanol exposure (PE) impairs midbrain dopaminergic (DA) neuron function, which might contribute to various cognitive and behavioral…”
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Moderate prenatal ethanol exposure leads to attention deficits in both male and female rats by Wang, Ruixiang, Martin, Connor D., Lei, Anna L., Hausknecht, Kathryn A., Ishiwari, Keita, Oubraim, Saida, Wang, An‐Li, Richards, Jerry B., Haj‐Dahmane, Samir, Shen, Roh‐Yu

“…Background Attention deficits caused by prenatal ethanol (EtOH) exposure (PE) are a prevalent condition in fetal alcohol spectrum disorders (FASDs)…”
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Cocaine self‐administration abolishes endocannabinoid‐mediated long‐term depression of glutamatergic synapses in the ventral tegmental area by Wang, Ruixiang, Hausknecht, Kathryn A., Gancarz‐Kausch, Amy M., Oubraim, Saida, Shen, Roh‐Yu, Haj‐Dahmane, Samir

“…Drugs of abuse, including cocaine, alter the mechanisms underpinning synaptic plasticity, including long‐term potentiation of glutamatergic synapses in the…”
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Prenatal ethanol exposure impairs sensory processing and habituation of visual stimuli, effects normalized by postnatal environmental enrichment by Wang, Ruixiang, Martin, Connor D., Lei, Anna L., Hausknecht, Kathryn A., Turk, Marisa, Micov, Veronika, Kwarteng, Francis, Ishiwari, Keita, Oubraim, Saida, Wang, An‐Li, Richards, Jerry B., Haj‐Dahmane, Samir, Shen, Roh‐Yu

“…Abstract Background Individuals with fetal alcohol spectrum disorders (FASD) often show processing deficits in all sensory modalities. Using an operant light…”
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Fatty acid binding protein deletion prevents stress‐induced preference for cocaine and dampens stress‐induced corticosterone levels by Hamilton, John, Marion, Matthew, Figueiredo, Antonio, Clavin, Brendan H., Deutsch, Dale, Kaczocha, Martin, Haj‐Dahmane, Samir, Thanos, Panayotis K.

“…Genetic and pharmacological manipulation of endocannabinoid (eCB) signaling has previously been shown to have an important role on the rewarding properties of…”
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D2-like dopamine receptor activation excites rat dorsal raphe 5-HT neurons in vitro by Haj-Dahmane, Samir

“…The aim of the present study was to investigate the effect of dopamine (DA) on the excitability of dorsal raphe nucleus (DRN) 5‐hydroxytryptamine (5‐HT)…”
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Target-specific modulation of the descending prefrontal cortex inputs to the dorsal raphe nucleus by cannabinoids by Geddes, Sean D., Assadzada, Saleha, Lemelin, David, Sokolovski, Alexandra, Bergeron, Richard, Haj-Dahmane, Samir, Béïque, Jean-Claude

“…Serotonin (5-HT) neurons located in the raphe nuclei modulate a wide range of behaviors by means of an expansive innervation pattern. In turn, the raphe…”
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Prenatal ethanol exposure impairs sensory processing and habituation to visual stimuli, effects normalized by enrichment of postnatal environmental by Wang, Ruixiang, Martin, Connor D., Lei, Anna L., Hausknecht, Kathryn A., Turk, Marisa, Micov, Veronika, Kwarteng, Francis, Ishiwari, Keita, Oubraim, Saida, Wang, An‐Li, Richards, Jerry B., Haj‐Dahmane, Samir, Shen, Roh‐Yu

“…Background Individuals with fetal alcohol spectrum disorders (FASD) often show processing deficits in all sensory modalities. Using an operant light…”
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Fatty Acid-Binding Protein 5 Modulates Brain Endocannabinoid Tone and Retrograde Signaling in the Striatum by Fauzan, Mohammad, Oubraim, Saida, Yu, Mei, Glaser, Sherrye T, Kaczocha, Martin, Haj-Dahmane, Samir

“…The endocannabinoid (eCB) anandamide (AEA) and 2-arachidonoylglycerol (2-AG) are endogenous lipid neurotransmitters that regulate an array of physiological…”
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Prenatal ethanol exposure causes anxiety-like phenotype and alters synaptic nitric oxide and endocannabinoid signaling in dorsal raphe nucleus of adult male rats by Oubraim, Saida, Wang, Ruixiang, Hausknecht, Kathryn, Kaczocha, Martin, Shen, Roh-Yu, Haj-Dahmane, Samir

“…Mood disorders, including anxiety and depression caused by prenatal ethanol exposure (PE) are prevalent conditions in fetal alcohol spectrum disorders (FASDs)…”
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Fatty acid binding proteins are novel modulators of synaptic epoxyeicosatrienoic acid signaling in the brain by Glaser, Sherrye T., Jayanetti, Kalani, Oubraim, Saida, Hillowe, Andrew, Frank, Elena, Jong, Jason, Wang, Liqun, Wang, Hehe, Ojima, Iwao, Haj-Dahmane, Samir, Kaczocha, Martin

“…Fatty acid binding proteins (FABPs) govern intracellular lipid transport to cytosolic organelles and nuclear receptors. More recently, FABP5 has emerged as a…”
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Regulation of plasticity of glutamate synapses by endocannabinoids and the cyclic‐AMP/protein kinase A pathway in midbrain dopamine neurons by Haj‐Dahmane, Samir, Shen, Roh‐Yu

“…Endocannabinoids (eCBs) are lipid signalling molecules which play a key role in the regulation of synaptic transmission and plasticity in the central nervous…”
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Endocannabinoids suppress excitatory synaptic transmission to dorsal raphe serotonin neurons through the activation of presynaptic CB1 receptors by Haj-Dahmane, Samir, Shen, Roh-Yu

“…Endocannabinoid signaling in the dorsal raphe (DR) has recently been implicated in the regulation of anxiety and depression. However, the cellular mechanisms…”
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Melatonin receptor activation increases glutamatergic synaptic transmission in the rat medial lateral habenula by Evely, Katherine M., Hudson, Randall L., Dubocovich, Margarita L., Haj-dahmane, Samir

“…ABSTRACT Melatonin (MLT) is secreted from the pineal gland and mediates its physiological effects through activation of two G protein‐coupled receptors, MT1…”
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Endocannabinoids mediate the glucocorticoid‐induced inhibition of excitatory synaptic transmission to dorsal raphe serotonin neurons by Wang, Jue, Shen, Roh‐Yu, Haj‐Dahmane, Samir

“…Key points •  The modulation of the serotonin system by glucocorticoids plays a central role in the regulation of stress responses. However, the mechanisms by…”
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Potentiation of Glutamatergic Synaptic Transmission Onto Dorsal Raphe Serotonergic Neurons in the Valproic Acid Model of Autism by Wang, Ruixiang, Hausknecht, Kathryn, Shen, Roh-Yu, Haj-Dahmane, Samir

“…Autism spectrum disorder (ASD) is characterized by social and communicative impairments and increased repetitive behaviors. These symptoms are often comorbid…”
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Oxytocin excites dorsal raphe serotonin neurons and bidirectionally gates their glutamate synapses by Oubraim, Saida, Shen, Roh-Yu, Haj-Dahmane, Samir

“…Oxytocin (OXT) modulates wide spectrum of social and emotional behaviors via modulation of numerous neurotransmitter systems, including serotonin (5-HT)…”
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Tonic Endocannabinoid Signaling Gates Synaptic Plasticity in Dorsal Raphe Nucleus Serotonin Neurons Through Peroxisome Proliferator-Activated Receptors by Oubraim, Saida, Wang, Ruixiang, Hausknecht, Kathryn A, Shen, Roh-Yu, Haj-Dahmane, Samir

“…Endocannabinoids (eCBs), which include 2-arachidonoylglycerol (2-AG) and anandamide (AEA) are lipid signaling molecules involved in the regulation of an array…”
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Prenatal ethanol exposure leads to persistent anxiety-like behavior during adulthood indicated by reduced horizontal and vertical exploratory behaviors by Wang, An-Li, Micov, Veronika B, Kwarteng, Francis, Wang, Ruixiang, Hausknecht, Kathryn A, Oubraim, Saida, Haj-Dahmane, Samir, Shen, Roh-Yu

“…Fetal alcohol spectrum disorders (FASD) caused by prenatal ethanol exposure (PE) consist of many cognitive/behavioral deficits. Studies have reported that PE…”
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