Search Results - "Haitham, Elleuch"

Spectral study of phosphonium salts synthesized from Michael acceptors by Haitham, Elleuch, Yaccoubi, Ferid

“…The synthesis of new phosphonium salts derived from Michael acceptors via a one-pot reaction process and the study of their NMR characteristics is described…”
Get full text

Selection of electron-deficient substances as antifungal candidates by Mihoubi, Wafa, Elleuch, Haitham, Boudabbous, Manel, Ketata, Emna, Borgi, Ines, Rezgui, Farhat, Gargouri, Ali

“…A new class of bioactive compounds synthesized from Morita-Baylis–Hillman adducts (MBH) showed antioxidant and anti-melanogenesis activities.Therefore, the…”
Get full text

Potential antioxidant activity of Morita-Baylis-Hillman adducts by Elleuch, Haitham, Mihoubi, Wafa, Mihoubi, Mohamed, Ketata, Emna, Gargouri, Ali, Rezgui, Farhat

“…[Display omitted] The wide variety of potent biological activities of Morita-Baylis-Hillman adducts (MBH) encouraged us to synthesize new series of products…”
Get full text

Regioselective Oxidation of Tetrahydronaphthalenes to α‑Tetralone Derivatives Using DDQ as Oxidizing Agent: Synthesis and Evaluation of Antibacterial and Antifungal Activities by Meddeb, Ahmed, Thebti, Amal, Elleuch, Haitham, Ayari, Sami, Bouslama, Lamjed, Ouzari, Hadda-Imene

“…An easy and efficient approach for the synthesis of highly regioselective functionalized dihydronaphthalen-1­(2H)-one family of α-tetralones from…”
Get full text

First DMAP-mediated direct conversion of Morita-Baylis-Hillman alcohols into γ-ketoallylphosphonates: Synthesis of γ-aminoallylphosphonates by Ayadi, Marwa, Elleuch, Haitham, Vrancken, Emmanuel, Rezgui, Farhat

“…An efficient synthesis of a series of γ-ketoallylphosphonates through a direct conversion of both primary and secondary Morita-Baylis-Hillman (MBH) alcohols by…”
Get full text

An efficient one-pot synthesis of benzofurans from functionalized tetrahydronaphtalenes by Meddeb, Ahmed, Elleuch, Haitham, Ayari, Sami

“…A simple, rapid and highly regioselective approach has been achieved for the cyclization of tetrahydronaphthalenes (THN) using α-bromoketones, resulting in the…”
Get full text

Direct nucleophilic substitutions of allylic alcohols with 1,3-dicarbonyl compounds: Synthetic design, mechanistic aspects and applications by Mhasni, Olfa, Elleuch, Haitham, Rezgui, Farhat

“…The nucleophilic allylic substitutions have become one of the most powerful tools for the construction of carbon-carbon and carbon-heteroatom bonds in organic…”
Get full text

Chemoselective reaction of ethane-1,2-dithiol, hydrazines, and hydroxylamine onto γ-keto allyl phosphonates and phosphine oxides by Elleuch, Haïtham, Baioui, Narjes, Bouajila, Jalloul, Rezgui, Farhat

Get full text

Al(OiPr)3 as an effective catalyst for the enhancement of Meerwein−Ponndorf−Verley (MPV) reductions of Morita-Baylis-Hillman (MBH) cyclic alcohols by Sindi, Kais, Elleuch, Haitham, Ayari, Sami, Mansour, Lamjed, Sauthier, Mathieu, hamdi, Naceur

“…•Regioselective and stereoselective reduction of cyclic MBH alcohols mediated by Al(OiPr)3 in isopropyl alcohol.•Meerwein-Ponndorf-Verley (MPV) method for the…”
Get full text

Synthesis of a Series of γ‑Keto Allyl Phosphonates by Elleuch, Haitham, Ayadi, Marwa, Bouajila, Jalloul, Rezgui, Farhat

“…Under solvent-free conditions and at 80 °C, a DMAP- or imidazole-mediated clean and rapid conversion of cyclic Morita–Baylis–Hillman (MBH) acetates into the…”
Get full text

New Morita-Baylis-Hillman (MBH) phosphonium salts from alcohols to the synthesis of 2-alkenyl- and 2-alkylidenecyclohexenones by Elleuch, Haitham, Msalbi, Dhouha, Mhasni, Olfa, Yaccoubi, Ferid, Aifa, Sami, Legros, Julien, Rezgui, Farhat

“…•Synthetic for 2- and 3-cyclohexenone derivatives.•Phosphonium salts cyclic MBH adducts.•One-pot conversion of MBH alcohols into the corresponding phosphonium…”
Get full text

Antiplatelet activity and toxicity profile of novel phosphonium salts derived from Michael reaction by Haffouz, Asma, Elleuch, Haitham, Khemakhem, Bassem, Ben Amor, Ikram, Jerbi, Amira, Gargouri, Jalel, Sahli, Emna, Mhadhbi, Noureddine, Ghalla, Houcine, Rezgui, Farhat, Gargouri, Ali, HadjKacem, Basma

“…•Novel four phosphonium salts inhibit ADP and collagen-induced platelet aggregation.•The four molecules inhibit platelet secretion and GPIIb/IIIa…”
Get full text

Synthesis, crystal structure, spectroscopic, and Hirshfeld surface study of a new functionalized α-hydroxyphosphonate complex of tin(IV) chloride by Zairi, Sondes, Selmi, Wafa, Elleuch, Haitham, Faouzi Zid, Mohamed, Rezgui, Farhat

“…A new octahedral [SnCl 4 L·H 2 O] complex (L = γ-keto allyl phosphonate) (1) was prepared and characterized by multinuclear ( 1 H, 13 C, 31 P, and 119 Sn) NMR…”
Get full text

WITHDRAWN: Acetate derivative of Morita –Baylis-Hillman adducts (MBH): A powerful antifungal by Mihoubi, Wafa, Elleuch, Haitham, Ketata, Emna, Gargouri, Ali

Get full text

Transition-metal-free nucleophilic allylic substitutions of Morita-Baylis-Hillman bromides with aliphatic and aromatic amines by Baioui, Narjes, Elleuch, Haitham, Rezgui, Farhat

“…A simple protocol for the preparation of functionalized allylic amines under mild, transition-metal-free conditions from the reaction of Morita-Baylis-Hillman…”
Get full text

Anti-melanogenesis potential of a new series of Morita-Baylis-Hillman adducts in B16F10 melanoma cell line by Ketata, Emna, Elleuch, Haitham, Neifar, Aref, Mihoubi, Wafa, Ayadi, Wajdi, Marrakchi, Naziha, Rezgui, Farhat, Gargouri, Ali

“…[Display omitted] •Some Morita-Baylis-Hillman adducts behave as reversible tyrosinase inhibitors.•The compounds 1a and 3f are competitive inhibitors while 2b…”
Get full text

Synthesis, spectroscopic characterization and solution behavior of new tin tetrachloride adducts with γ-keto allyl phosphonates by Elleuch, Haitham, Sanhoury, M.A.K., Rezgui, F.

“…Four new octahedral complexes of the type [SnCl4L2] (L = γ-keto allyl phosphonate) (1–4) were prepared and characterized by multinuclear (1H, 13C, 31P and…”
Get full text