Search Results - "Haisma, H.J."

Targeted adenovirus mediated inhibition of NF-κB-dependent inflammatory gene expression in endothelial cells in vitro and in vivo by Kułdo, J.M., Ásgeirsdóttir, S.A., Zwiers, P.J., Bellu, A.R., Rots, M.G., Schalk, J.A.C., Ogawara, K.I., Trautwein, C., Banas, B., Haisma, H.J., Molema, G., Kamps, J.A.A.M.

“…In chronic inflammatory diseases the endothelium expresses mediators responsible for harmful leukocyte infiltration. We investigated whether targeted delivery…”
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1068 Increasing the efficiency of gene therapy by using protein transduction domains by Sen, G.P, Beerens, A.M.J, Haisma, H.J

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Targeted cancer gene therapy: the flexibility of adenoviral gene therapy vectors by Rots, M.G., Curiel, D.T., Gerritsen, W.R., Haisma, H.J.

“…Recombinant adenoviral vectors are promising reagents for therapeutic interventions in humans, including gene therapy for biologically complex diseases like…”
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Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX‐GA3 in combination with a monoclonal antibody β‐glucuronidase conjugate by Houba, P.H.J., Boven, E., van der Meulen‐Muileman, I.H., Leenders, R.G.G., Scheeren, J.W., Pinedo, H.M., Haisma, H.J.

“…A glucuronide doxorubicin prodrug N‐[4‐doxorubicin‐N‐carbonyl (oxymethyl) phenyl] O‐β‐glucuronyl carbamate (DOX‐GA3) has been developed to improve the…”
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One-year audit of admissions to the Intensive Care Unit of the Queen Elizabeth Central Hospital, Blantyre by Size, M., Borgstein, E.S. and Haisma, H.J.

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Prostate specific membrane antigen (PSMA) is a tissue-specific target for adenoviral transduction of prostate cancer in vitro by Kraaij, R., van Rijswijk, A.L.C.T., Oomen, M.H.A., Haisma, H.J., Bangma, C.H.

“…Background Adenovirus binds to the coxsackievirus and adenovirus receptor (CAR) as a first step in the process of cellular infection. This dependence on CAR…”
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Highly efficient and carcinoma-specific adenoviral replication restricted by the EGP-2 promoter by Gommans, W.M., McLaughlin, P.M.J., Schalk, J.A.C., Groothuis, G.M.M., Haisma, H.J., Rots, M.G.

“…Although some successes have been reported using adenoviral vectors for the treatment of cancer, adenoviral cancer gene therapy is still hampered by the lack…”
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Towards a double controlled conditionally replicative adenovirus for potent and specific melanoma cell kill by Gommans, W.M., Oosterhuis, D., Dmitriev, I., Schaack, J., Curiel, D.T., Haisma, H.J., Rots, M.G.

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Epidermal growth factor receptor targeting of replication competent adenovirus enhances cytotoxicity in bladder cancer by van der Poel, H G, Molenaar, B, van Beusechem, V W, Haisma, H J, Rodriguez, R, Curiel, D T, Gerritsen, W R

“…We evaluated the delivery and oncolytic potential of targeted replication competent adenoviruses in bladder cancer lines. Seven established human bladder…”
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The effect of artificial ventilation on peri-contusional and remote cerebral perfusion (a case study with PET) by de Jong, B.M., de Jong, J.B., Haisma, H.J., van der Naalt, J., Willemsen, A.T.M.

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Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody ?-glucuronidase conjugate by Houba, P.H.J., Boven, E., van der Meulen-Muileman, I.H., Leenders, R.G.G., Scheeren, J.W., Pinedo, H.M., Haisma, H.J.

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Immuno-liposomes bearing enzymes (immuno-enzymosomes) for site-specific activation of anticancer prodrugs by Storm, G, Vingerhoeds, M.H, Crommelin, D.J.A, Haisma, H.J

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Immunoliposomes as enzyme-carriers (immuno-enzymosomes) for antibody-directed enzyme prodrug therapy (ADEPT) : Optimization of prodrug activating capacity by VINGERHOEDS, M. H, HAISMA, H. J, BELLIOT, S. O, SMIT, R. H. P, CROMMELIN, D. J. A, STORM, G

“…Immuno-enzymosomes are tumor-specific immunoliposomes bearing enzymes on their surface. These enzymes are capable of converting relatively nontoxic prodrugs…”
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One-year audit of admissions to the Intensive Care Unit of the Queen Elizabeth Central Hospital, Blantyre by Size, M., Borgstein, E.S. and Haisma, H.J.

“…The intensive care unit at Queen Elizabeth Central Hospital (QECH) has 4 beds and offers level 2 care. A retrospective audit of all admissions to the unit…”
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Design of immuno-enzymosomes with maximum enzyme targeting capability: effect of the enzyme density on the enzyme targeting capability and cell binding properties by Fonseca, M.J., Haisma, H.J., Klaassen, S., Vingerhoeds, M.H., Storm, G.

“…Immuno-enzymosomes have been proposed for the targeting of enzymes to cancer cells to achieve site specific activation of anticancer prodrugs. Previously, we…”
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A new application for liposomes in cancer therapy: Immunoliposomes bearing enzymes (immuno-enzymosomes) for site-specific activation of prodrugs by Vingerhoeds, M.H., Haisma, H.J., van Muijen, M., van de Rijt, R.B.J., Crommelin, D.J.A., Storm, G.

“…We have tested a new type of immunoliposomes which may effectively mediate the targeting of enzymes to be used for site-specific prodrug activation…”
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A new application for liposomes in cancer therapy by Vingerhoeds, M.H., Haisma, H.J., van Muijen, M., van de Rijt, R.B.J., Crommelin, D.J.A., Storm, G.

“…We have tested a new type of immunoliposomes which may effectively mediate the targeting of enzymes to be used for site‐specific prodrug activation…”
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Distribution and pharmacokinetics of radiolabeled monoclonal antibody OC 125 after intravenous and intraperitoneal administration in gynecologic tumors by Haisma, H J, Moseley, K R, Battaile, A, Griffiths, T C, Knapp, R C

“…Radiolabeled monoclonal antibodies may be useful for radioimmunotherapy of gynecologic tumors. Iodine 131-labeled F(ab')2 fragments of a monoclonal antibody,…”
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Neuroleptic malignant syndrome by Haisma, H J, Constantinou, E, Chinyanga, H M

“…While on holiday in Zimbabwe, a forty-one year old woman with a long history of intermittent psychiatric illness developed what was diagnosed as neuroleptic…”
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Higher ADCC of murine peritoneal cells after immunization with allogenic tumor cells as compared with stimulation by adriamycin, BCG, and thioglycolate by Haisma, H J, Ligtenberg, M, Dullens, H F, Den Otter, W

“…Normal peritoneal cells or spleen cells from C57BL mice could not lyse SRBC in an ADCC assay. After intraperitoneal injection of Adriamycin, BCG or…”
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