Search Results - "Haipeng, Sun"
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Branched chain amino acid metabolic reprogramming in heart failure
Published in Biochimica et biophysica acta (01-12-2016)“…Metabolic remodeling is a hall-mark of cardiac maturation and pathology. The switch of substrate utilization from glucose to fatty acid is observed during…”
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Defective Branched-Chain Amino Acid Catabolism Disrupts Glucose Metabolism and Sensitizes the Heart to Ischemia-Reperfusion Injury
Published in Cell metabolism (07-02-2017)“…Elevated levels of branched-chain amino acids (BCAAs) have recently been implicated in the development of cardiovascular and metabolic diseases, but the…”
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Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance
Published in Diabetes (New York, N.Y.) (01-09-2019)“…Recent studies implicate a strong association between elevated plasma branched-chain amino acids (BCAAs) and insulin resistance (IR). However, a causal…”
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Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure
Published in Circulation (New York, N.Y.) (24-05-2016)“…BACKGROUND—Although metabolic reprogramming is critical in the pathogenesis of heart failure, studies to date have focused principally on fatty acid and…”
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Perioperative outcomes of thoracoscopic versus non-thoracoscopic minimally invasive repair of pectus excavatum: a systematic review and meta-analysis
Published in Journal of cardiothoracic surgery (12-10-2024)“…Pectus excavatum is the most common chest wall deformity, with the Nuss procedure being the preferred surgical approach for correction. However, the decision…”
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Advancements and Policy Implications of Green Hydrogen Production from Renewable Sources
Published in Energies (Basel) (01-07-2024)“…With the increasingly severe climate change situation and the trend of green energy transformation, the development and utilization of hydrogen energy has…”
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Staphylococcus aureus AI-2 Quorum Sensing Associates with the KdpDE Two-Component System To Regulate Capsular Polysaccharide Synthesis and Virulence
Published in Infection and Immunity (01-08-2010)“…Autoinducer 2 (AI-2) is widely recognized as a signal molecule for intra- and interspecies communication in Gram-negative bacteria, but its signaling function…”
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Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy
Published in Nature communications (01-04-2022)“…Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived…”
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The Staphylococcus aureus KdpDE Two-Component System Couples Extracellular K+ Sensing and Agr Signaling to Infection Programming
Published in Infection and Immunity (01-06-2011)“…OA Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Edge-Cloud Collaborative Defense against Backdoor Attacks in Federated Learning
Published in Sensors (Basel, Switzerland) (17-01-2023)“…Federated learning has a distributed collaborative training mode, widely used in IoT scenarios of edge computing intelligent services. However, federated…”
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Efficacy and safety of different systemic drugs in the treatment of uremic pruritus among hemodialysis patients: a network meta-analysis based on randomized clinical trials
Published in Frontiers in medicine (2024)“…This network meta-analysis was to analyze and rank the efficacy and safety of different systemic drugs in the treatment of uremic pruritus (UP) among…”
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BCAA Catabolic Defect Alters Glucose Metabolism in Lean Mice
Published in Frontiers in physiology (04-09-2019)“…Recent studies show branched-chain amino acid (BCAA) catabolic pathway is defective in obese animals and humans, contributing to the pathogenesis of insulin…”
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Single-cell Mayo Map (scMayoMap): an easy-to-use tool for cell type annotation in single-cell RNA-sequencing data analysis
Published in BMC biology (20-10-2023)“…Single-cell RNA-sequencing (scRNA-seq) has become a widely used tool for both basic and translational biomedical research. In scRNA-seq data analysis, cell…”
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Therapeutic Effect of Targeting Branched-Chain Amino Acid Catabolic Flux in Pressure-Overload Induced Heart Failure
Published in Journal of the American Heart Association (04-06-2019)“…Background Branched-chain amino acid (BCAA) catabolic defect is an emerging metabolic hallmark in failing hearts in human and animal models. The therapeutic…”
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BCKDH kinase promotes hepatic gluconeogenesis independent of BCKDHA
Published in Cell death & disease (10-10-2024)“…Elevated circulating branched-chain amino acids (BCAAs) are tightly linked to an increased risk in the development of type 2 diabetes mellitus. The rate…”
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Manganese ferrite nanoparticles enhanced biohydrogen production from mesophilic and thermophilic dark fermentation
Published in Energy reports (01-11-2021)“…In this work, Manganese ferrite nanoparticles (MnFe 2O4 NPs) were synthesized, and their potential to increase the biohydrogen (bio-H2) yield of glucose in…”
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Serum branched chain amino acids: an effective indicator of diabetic kidney disease
Published in Frontiers in endocrinology (Lausanne) (27-11-2023)“…In recent years, there has been a growing association between elevated circulating levels of branched-chain amino acids (BCAA) and diabetes mellitus. However,…”
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Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway
Published in Frontiers in physiology (25-10-2017)“…Recent studies have linked branched-chain amino acid (BCAA) with numerous metabolic diseases. However, the molecular basis of BCAA's roles in metabolic…”
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A new branch connecting thermogenesis and diabetes
Published in Nature metabolism (01-09-2019)“…Systemic accumulation of branched-chain amino acids (BCAAs) is a major metabolic hallmark and contributor to insulin resistance associated with obesity. A…”
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