Search Results - "Haipek, Carrie A."
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Serine 518 phosphorylation modulates merlin intramolecular association and binding to critical effectors important for NF2 growth suppression
Published in Oncogene (04-11-2004)“…The neurofibromatosis 2 (NF2) tumor suppressor protein, merlin, functions as a negative growth regulator; however, the molecular mechanisms that underlie…”
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2
Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function
Published in Oncogene (15-01-2004)“…The neurofibromatosis 2 (NF2) tumor suppressor gene product, merlin, belongs to the ezrin-radixin-moesin (ERM) subgroup of the Protein 4.1 family, which links…”
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3
Akt-Dependent Cell Size Regulation by the Adhesion Molecule on Glia Occurs Independently of Phosphatidylinositol 3-Kinase and Rheb Signaling
Published in Molecular and Cellular Biology (01-04-2005)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Protein 4.1 Tumor Suppressor, DAL-1, Impairs Cell Motility, But Regulates Proliferation in a Cell-Type-Specific Fashion
Published in Neurobiology of disease (01-04-2001)“…The neurofibromatosis 2 (NF2) tumor suppressor belongs to the Protein 4.1 family of molecules that link the actin cytoskeleton to cell surface glycoproteins…”
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5
Functional significance of S6K overexpression in meningioma progression
Published in Annals of neurology (01-08-2004)“…One common genetic change in anaplastic meningiomas is amplification of chromosome 17q23 containing the S6 kinase (S6K) gene. We show, for the first time to…”
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The NF2 interactor, hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), associates with merlin in the 'open' conformation and suppresses cell growth and motility
Published in Human molecular genetics (01-04-2001)“…The neurofibromatosis 2 tumor suppressor protein, merlin or schwannomin, functions as a negative growth regulator; however, its mechanism of action is not…”
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7
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44
Published in Genes & development (15-04-2001)“…The neurofibromatosis-2 (NF2) gene encodes merlin, an ezrin-radixin-moesin-(ERM)-related protein that functions as a tumor suppressor. We found that merlin…”
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8
Functional analysis of neurofibromatosis 2 (NF2) missense mutations
Published in Human molecular genetics (01-07-2001)“…Neurofibromatosis 2 (NF2) is a tumor predisposition syndrome in which affected individuals develop nervous system tumors at an increased frequency. The most…”
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Xeroderma pigmentosum variant cells are not defective in the repair of (6-4) photoproducts
Published in International journal of radiation biology and related studies in physics, chemistry and medicine (1987)“…Using radioimmunoassays specific for (6-4) photoproducts and cyclobutane dimers, Xeroderma pigmentosum variant cells appear to have a normal capacity for the…”
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10
Biological consequences of photoproducts in mammalian cell DNA partially substituted with 5-bromouracil
Published in International journal of radiation biology and related studies in physics, chemistry and medicine (01-01-1984)“…The response of Chinese hamster ovary cells in which 10 per cent of the thymine of one DNA strand was substituted with bromouracil (BU) was compared with…”
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11
Further characterisation of a polyclonal antiserum for DNA photoproducts: the use of different labelled antigens to control its specificity
Published in Mutation research (01-09-1985)“…Synthetic polynucleotides irradiated with far (254 nm) or near (320 nm) UV-light were used to characterise 3 different radioimmunoassay systems. Antiserum…”
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