Search Results - "Haipek, Carrie"

Serine 518 phosphorylation modulates merlin intramolecular association and binding to critical effectors important for NF2 growth suppression by RONG RONG, SURACE, Ezequiel I, HAIPEK, Carrie A, GUTMANN, David H, KEQIANG YE

“…The neurofibromatosis 2 (NF2) tumor suppressor protein, merlin, functions as a negative growth regulator; however, the molecular mechanisms that underlie…”
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Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function by SURACE, Ezequiel I, HAIPEK, Carrie A, GUTMANN, David H

“…The neurofibromatosis 2 (NF2) tumor suppressor gene product, merlin, belongs to the ezrin-radixin-moesin (ERM) subgroup of the Protein 4.1 family, which links…”
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Functional significance of S6K overexpression in meningioma progression by Surace, Ezequiel I., Lusis, Eriks, Haipek, Carrie A., Gutmann, David H.

“…One common genetic change in anaplastic meningiomas is amplification of chromosome 17q23 containing the S6 kinase (S6K) gene. We show, for the first time to…”
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Akt-Dependent Cell Size Regulation by the Adhesion Molecule on Glia Occurs Independently of Phosphatidylinositol 3-Kinase and Rheb Signaling by Scheidenhelm, Danielle K., Cresswell, Jennifer, Haipek, Carrie A., Fleming, Timothy P., Mercer, Robert W., Gutmann, David H.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Protein 4.1 Tumor Suppressor, DAL-1, Impairs Cell Motility, But Regulates Proliferation in a Cell-Type-Specific Fashion by Gutmann, David H., Hirbe, Angela C., Huang, Zhi-yong, Haipek, Carrie A.

“…The neurofibromatosis 2 (NF2) tumor suppressor belongs to the Protein 4.1 family of molecules that link the actin cytoskeleton to cell surface glycoproteins…”
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The NF2 interactor, hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), associates with merlin in the 'open' conformation and suppresses cell growth and motility by GUTMANN, David H, HAIPEK, Carrie A, BURKE, Stephen P, SUN, Chun-Xiao, SCOLES, Daniel R, PULST, Stefan M

“…The neurofibromatosis 2 tumor suppressor protein, merlin or schwannomin, functions as a negative growth regulator; however, its mechanism of action is not…”
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Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome by Mardis, Elaine R, Ding, Li, Dooling, David J, Larson, David E, McLellan, Michael D, Chen, Ken, Koboldt, Daniel C, Fulton, Robert S, Fulton, Lucinda A, Delehaunty, Kim D, McGrath, Sean D, Locke, Devin P, Magrini, Vincent J, Abbott, Rachel M, Vickery, Tammi L, Reed, Jerry S, Robinson, Jody S, Wylie, Todd, Smith, Scott M, Carmichael, Lynn, Eldred, James M, Harris, Christopher C, Walker, Jason, Peck, Joshua B, Du, Feiyu, Dukes, Adam F, Sanderson, Gabriel E, Brummett, Anthony M, Clark, Eric, McMichael, Joshua F, Meyer, Rick J, Schindler, Jonathan K, Pohl, Craig S, Wallis, John W, Shi, Xiaoqi, Lin, Ling, Schmidt, Heather, Tang, Yuzhu, Haipek, Carrie, Wiechert, Madeline E, Ivy, Jolynda V, Kalicki, Joelle, Elliott, Glendoria, Ries, Rhonda E, Payton, Jacqueline E, Westervelt, Peter, Tomasson, Michael H, Watson, Mark A, Baty, Jack, Heath, Sharon, Shannon, William D, Nagarajan, Rakesh, Link, Daniel C, Walter, Matthew J, Graubert, Timothy A, DiPersio, John F, Wilson, Richard K, Ley, Timothy J

“…A comparison of the genomic sequence of a tumor sample from a patient with acute myeloid leukemia (AML) and that of a normal skin sample from the same patient…”
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The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44 by Morrison, H, Sherman, L S, Legg, J, Banine, F, Isacke, C, Haipek, C A, Gutmann, D H, Ponta, H, Herrlich, P

“…The neurofibromatosis-2 (NF2) gene encodes merlin, an ezrin-radixin-moesin-(ERM)-related protein that functions as a tumor suppressor. We found that merlin…”
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Increased Expression of the NF2 Tumor Suppressor Gene Product, Merlin, Impairs Cell Motility, Adhesion and Spreading by Gutmann, David H., Sherman, Larry, Seftor, Liz, Haipek, Carrie, Hoang Lu, Kimberly, Hendrix, Mary

“…The neurofibromatosis 2 (NF2) gene product, merlin, is a tumor suppressor protein mutated in schwanno-mas and several other tumors. Merlin, which shares…”
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Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations by Gutmann, David H., Haipek, Carrie Ann, Hoang Lu, Kimberly

“…The neurofibromatosis 2 (NF2) tumor suppressor gene product, merlin (schwannomin) forms an intramolecular association that is required for negative growth…”
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Functional analysis of neurofibromatosis 2 (NF2) missense mutations by GUTMANN, David H, HIRBE, Angela C, HAIPEK, Carrie A

“…Neurofibromatosis 2 (NF2) is a tumor predisposition syndrome in which affected individuals develop nervous system tumors at an increased frequency. The most…”
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Functional analysis of the relationship between the neurofibromatosis 2 tumor suppressor and its binding partner, hepatocyte growth factor-regulated tyrosine kinase substrate by Sun, Chun-Xiao, Haipek, Carrie, Scoles, Daniel R., Pulst, Stefan M., Giovannini, Marco, Komada, Masayuki, Gutmann, David H.

“…Individuals with the neurofibromatosis 2 (NF2) inherited tumor predisposition syndrome are prone to the development of nervous system tumors, including…”
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Genetic heterogeneity of stably transfected cell lines revealed by expression profiling with oligonucleotide microarrays by Oh, Min-Kyu, Scoles, Daniel R., Haipek, Carrie, Strand, Andrew D., Gutmann, David H., Olson, James M., Pulst, Stefan-M.

“…Large‐scale gene expression measurements with oligonucleotide microarrays have contributed tremendously to biological research. However, to distinguish between…”
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Cloning and identification of annexin II as an autocrine/paracrine factor that increases osteoclast formation and bone resorption by Takahashi, S, Reddy, S V, Chirgwin, J M, Devlin, R, Haipek, C, Anderson, J, Roodman, G D

“…Autocrine products of osteoclasts such as interleukin-6 may play an important role in normal osteoclast formation and activity. To identify novel stimulatory…”
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Increased expression of the NF2 tumor suppressor gene product, merlin, impairs cell motility, adhesionand spreading by Gutmann, D H, Sherman, L, Seftor, L, Haipek, C, Hoang Lu, K, Hendrix, M

“…The neurofibromatosis 2 ( NF2 ) gene product, merlin, is a tumor suppressor protein mutated in schwanno-mas and several other tumors. Merlin, which shares…”
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Xeroderma pigmentosum variant cells are not defective in the repair of (6-4) photoproducts by Mitchell, D L, Haipek, C A, Clarkson, J M

“…Using radioimmunoassays specific for (6-4) photoproducts and cyclobutane dimers, Xeroderma pigmentosum variant cells appear to have a normal capacity for the…”
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Biological consequences of photoproducts in mammalian cell DNA partially substituted with 5-bromouracil by Clarkson, J M, Haipek, C A

“…The response of Chinese hamster ovary cells in which 10 per cent of the thymine of one DNA strand was substituted with bromouracil (BU) was compared with…”
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Further characterisation of a polyclonal antiserum for DNA photoproducts: the use of different labelled antigens to control its specificity by Mitchell, D L, Haipek, C A, Clarkson, J M

“…Synthetic polynucleotides irradiated with far (254 nm) or near (320 nm) UV-light were used to characterise 3 different radioimmunoassay systems. Antiserum…”
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