Search Results - "Haipek, C A"

Functional analysis of neurofibromatosis 2 (NF2) missense mutations by GUTMANN, David H, HIRBE, Angela C, HAIPEK, Carrie A

“…Neurofibromatosis 2 (NF2) is a tumor predisposition syndrome in which affected individuals develop nervous system tumors at an increased frequency. The most…”
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The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44 by Morrison, H, Sherman, L S, Legg, J, Banine, F, Isacke, C, Haipek, C A, Gutmann, D H, Ponta, H, Herrlich, P

“…The neurofibromatosis-2 (NF2) gene encodes merlin, an ezrin-radixin-moesin-(ERM)-related protein that functions as a tumor suppressor. We found that merlin…”
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Characterization of chicken Nf2/merlin indicates regulatory roles in cell proliferation and migration by Chen, Y., Gutmann, D.H., Haipek, C.A., Martinsen, B.J., Bronner‐Fraser, M., Krull, C.E.

“…The neurofibromatosis 2 (NF2) tumor suppressor protein merlin, or schwannomin, functions as a negative growth regulator such that inactivating mutations in Nf2…”
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Serine 518 phosphorylation modulates merlin intramolecular association and binding to critical effectors important for NF2 growth suppression by RONG RONG, SURACE, Ezequiel I, HAIPEK, Carrie A, GUTMANN, David H, KEQIANG YE

“…The neurofibromatosis 2 (NF2) tumor suppressor protein, merlin, functions as a negative growth regulator; however, the molecular mechanisms that underlie…”
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(6-4)Photoproducts are removed from the DNA of UV-irradiated mammalian cells more efficiently than cyclobutane pyrimidine dimers by Mitchell, D L, Haipek, C A, Clarkson, J M

“…A polyclonal antiserum raised against UV-irradiated DNA can be used to assay cyclobutane pyrimidine dimers and Pyr(6-4)Pyo photoproducts specifically by…”
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The Protein 4.1 Tumor Suppressor, DAL-1, Impairs Cell Motility, But Regulates Proliferation in a Cell-Type-Specific Fashion by Gutmann, David H., Hirbe, Angela C., Huang, Zhi-yong, Haipek, Carrie A.

“…The neurofibromatosis 2 (NF2) tumor suppressor belongs to the Protein 4.1 family of molecules that link the actin cytoskeleton to cell surface glycoproteins…”
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The NF2 interactor, hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), associates with merlin in the 'open' conformation and suppresses cell growth and motility by GUTMANN, David H, HAIPEK, Carrie A, BURKE, Stephen P, SUN, Chun-Xiao, SCOLES, Daniel R, PULST, Stefan M

“…The neurofibromatosis 2 tumor suppressor protein, merlin or schwannomin, functions as a negative growth regulator; however, its mechanism of action is not…”
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Xeroderma pigmentosum variant cells are not defective in the repair of (6-4) photoproducts by Mitchell, D L, Haipek, C A, Clarkson, J M

“…Using radioimmunoassays specific for (6-4) photoproducts and cyclobutane dimers, Xeroderma pigmentosum variant cells appear to have a normal capacity for the…”
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Biological consequences of photoproducts in mammalian cell DNA partially substituted with 5-bromouracil by Clarkson, J M, Haipek, C A

“…The response of Chinese hamster ovary cells in which 10 per cent of the thymine of one DNA strand was substituted with bromouracil (BU) was compared with…”
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Further characterisation of a polyclonal antiserum for DNA photoproducts: the use of different labelled antigens to control its specificity by Mitchell, D L, Haipek, C A, Clarkson, J M

“…Synthetic polynucleotides irradiated with far (254 nm) or near (320 nm) UV-light were used to characterise 3 different radioimmunoassay systems. Antiserum…”
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Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations by Gutmann, David H., Haipek, Carrie Ann, Hoang Lu, Kimberly

“…The neurofibromatosis 2 (NF2) tumor suppressor gene product, merlin (schwannomin) forms an intramolecular association that is required for negative growth…”
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Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function by SURACE, Ezequiel I, HAIPEK, Carrie A, GUTMANN, David H

“…The neurofibromatosis 2 (NF2) tumor suppressor gene product, merlin, belongs to the ezrin-radixin-moesin (ERM) subgroup of the Protein 4.1 family, which links…”
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Neurofibromatosis 2 Tumor Suppressor Protein, Merlin, Forms Two Functionally Important Intramolecular Associations by Gutmann, D H, Haipek, CA, Lu, KH

“…The neurofibromatosis 2 (NF2) tumor suppressor gene product, merlin (schwannomin) forms an intramolecular association that is required for negative growth…”
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Akt-Dependent Cell Size Regulation by the Adhesion Molecule on Glia Occurs Independently of Phosphatidylinositol 3-Kinase and Rheb Signaling by Scheidenhelm, Danielle K., Cresswell, Jennifer, Haipek, Carrie A., Fleming, Timothy P., Mercer, Robert W., Gutmann, David H.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44 by Morrison, H, Sherman, L S, Legg, J, Banine, F, Isacke, C, Haipek, CA, Gutmann, D H, Ponta, H, Herrlich, P

“…The neurofibromatosis-2 (NF2) gene encodes merlin, an ezrin-radixin-moesin-(ERM)-related protein that functions as a tumor suppressor. We found that merlin…”
Get full text