Search Results - "Haines, Anthony S"

High quality genome annotation and expression visualisation of a mupirocin-producing bacterium by Haines, Anthony S, Kendrew, Steve G, Crowhurst, Nicola, Stephens, Elton R, Connolly, Jack, Hothersall, Joanne, Miller, Claire E, Collis, Andrew J, Huckle, Benjamin D, Thomas, Christopher M

“…Pseudomonas strain NCIMB10586, in the P. fluorescens subgroup, produces the polyketide antibiotic mupirocin, and has potential as a host for industrial…”
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Potentiation of curing by a broad-host-range self-transmissible vector for displacing resistance plasmids to tackle AMR by Lazdins, Alessandro, Maurya, Anand Prakash, Miller, Claire E, Kamruzzaman, Muhammad, Liu, Shuting, Stephens, Elton R, Lloyd, Georgina S, Haratianfar, Mona, Chamberlain, Melissa, Haines, Anthony S, Kreft, Jan-Ulrich, Webber, Mark A, Iredell, Jonathan, Thomas, Christopher M

“…Plasmids are potent vehicles for spread of antibiotic resistance genes in bacterial populations and often persist in the absence of selection due to efficient…”
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A natural plasmid uniquely encodes two biosynthetic pathways creating a potent anti-MRSA antibiotic by Fukuda, Daisuke, Haines, Anthony S, Song, Zhongshu, Murphy, Annabel C, Hothersall, Joanne, Stephens, Elton R, Gurney, Rachel, Cox, Russell J, Crosby, John, Willis, Christine L, Simpson, Thomas J, Thomas, Christopher M

“…Understanding how complex antibiotics are synthesised by their producer bacteria is essential for creation of new families of bioactive compounds…”
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Increased Abundance of IncP-1β Plasmids and Mercury Resistance Genes in Mercury-Polluted River Sediments: First Discovery of IncP-1β Plasmids with a Complex mer Transposon as the Sole Accessory Element by Smalla, Kornelia, Haines, Anthony S, Jones, Karen, Krögerrecklenfort, Ellen, Heuer, Holger, Schloter, Michael, Thomas, Christopher M

“…Although it is generally assumed that mobile genetic elements facilitate the adaptation of microbial communities to environmental stresses, environmental data…”
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An efficient stress-free strategy to displace stable bacterial plasmids by Hale, Lisa, Lazos, Orestis, Haines, Anthony, Thomas, Christopher

“…A key stage in determining the phenotype(s) conferred by a plasmid is its displacement, or 'curing,' to create a plasmid-free strain. However, many plasmids…”
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Genome Sequences of Three Acinetobacter baumannii Strains Assigned to the Multilocus Sequence Typing Genotypes ST2, ST25, and ST78 by ZARRILLI, Raffaele, GIANNOULI, Maria, ROCCO, Francesco, LOMAN, Nicholas J, HAINES, Anthony S, CONSTANTINIDOU, Chrystala, PALLEN, Mark J, TRIASSI, Maria, DI NOCERA, Pier Paolo

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The IncP-6 Plasmid Rms149 Consists of a Small Mobilizable Backbone with Multiple Large Insertions by HAINES, Anthony S, JONES, Karen, CHEUNG, Martin, THOMAS, Christopher M

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Diversity of IncP-9 plasmids of Pseudomonas by Sevastsyanovich, Yanina R, Krasowiak, Renata, Bingle, Lewis E. H, Haines, Anthony S, Sokolov, Sergey L, Kosheleva, Irina A, Leuchuk, Anastassia A, Titok, Marina A, Smalla, Kornelia, Thomas, Christopher M

“…1 School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK 2 Skryabin Institute of Biochemistry and Physiology of Microorganisms,…”
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Plasmids from freshwater environments capable of IncQ retrotransfer are diverse and include pQKH54, a new IncP-1 subgroup archetype by Haines, Anthony S, Akhtar, Parveen, Stephens, Elton R, Jones, Karen, Thomas, Christopher M, Perkins, Caroline D, Williams, Jacqueline R, Day, Martin J, Fry, John C

“…1 School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK 2 Cardiff School of Biosciences, Cardiff University, PO Box 915, Cardiff…”
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Iteron control of oriV function in IncP-1 plasmid RK2 by Maurya, Anand P., Lazdins, Alessandro, Wilson, Helen, Lloyd, Georgina S., Stephens, Elton R., Haines, Anthony S., Thomas, Christopher M.

“…Replication control of many plasmids is mediated by the balance between the positive and negative effects of Rep protein binding repeated sequences (iterons)…”
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A conserved motif flags acyl carrier proteins for β-branching in polyketide synthesis by Haines, Anthony S, Dong, Xu, Song, Zhongshu, Farmer, Rohit, Williams, Christopher, Hothersall, Joanne, Płoskoń, Eliza, Wattana-amorn, Pakorn, Stephens, Elton R, Yamada, Erika, Gurney, Rachel, Takebayashi, Yuiko, Masschelein, Joleen, Cox, Russell J, Lavigne, Rob, Willis, Christine L, Simpson, Thomas J, Crosby, John, Winn, Peter J, Thomas, Christopher M, Crump, Matthew P

“…Polyketide synthases infrequently insert β-branched monomers into their growing polyketide chains, the details of which are not well established…”
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Complete genome sequence of Pig-tailed macaque rhadinovirus 2 and its evolutionary relationship with rhesus macaque rhadinovirus and human herpesvirus 8/Kaposi's sarcoma-associated herpesvirus by Bruce, A Gregory, Thouless, Margaret E, Haines, Anthony S, Pallen, Mark J, Grundhoff, Adam, Rose, Timothy M

“…Two rhadinovirus lineages have been identified in Old World primates. The rhadinovirus 1 (RV1) lineage consists of human herpesvirus 8, Kaposi's…”
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Defining the genes for the final steps in biosynthesis of the complex polyketide antibiotic mupirocin by Pseudomonas fluorescens NCIMB10586 by Connolly, Jack A., Wilson, Amber, Macioszek, Malgorzata, Song, Zhongshu, Wang, Luoyi, Mohammad, Hadi H., Yadav, Mukul, di Martino, Maura, Miller, Claire E., Hothersall, Joanne, Haines, Anthony S., Stephens, Elton R., Crump, Matthew P., Willis, Christine L., Simpson, Thomas J., Winn, Peter J., Thomas, Christopher M.

“…The mupirocin trans- AT polyketide synthase pathway, provides a model system for manipulation of antibiotic biosynthesis. Its final phase involves removal of…”
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And on gloomy Sunday by Haines, Anthony S

“…A short story is presented…”
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Complete sequence of the IncPβ plasmid R751: implications for evolution and organisation of the IncP backbone by Thorsted, Peter B, Macartney, Donia P, Akhtar, Parveen, Haines, Anthony S, Ali, Nasima, Davidson, Philip, Stafford, Theresa, Pocklington, Michael J, Pansegrau, Werner, Wilkins, Brian M, Lanka, Erich, Thomas, Christopher M

“…The broad host range IncP plasmids are of particular interest because of their ability to promote gene spread between diverse bacterial species. To facilitate…”
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Effect of growth rate and incC mutation on symmetric plasmid distribution by the IncP‐1 partitioning apparatus by Bignell, Colin R., Haines, Anthony S., Khare, Dheeraj, Thomas, Christopher M.

“…The incC and korB genes of IncP‐1 plasmid RK2 encode homologues of ubiquitous ParA and ParB partitioning proteins of bacterial plasmids and chromosomes. Using…”
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Evidence that IncG (IncP-6) and IncU plasmids form a single incompatibility group by Haines, Anthony S., Cheung, Martin, Thomas, Christopher M.

“…The Escherichia coli IncG and IncU plasmid incompatibility groups were assigned in 1980 and 1981, respectively. Complete plasmid sequences have recently been…”
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Minimum Information about a Biosynthetic Gene cluster by Medema, Marnix H, Kottmann, Renzo, Yilmaz, Pelin, Cummings, Matthew, Blin, Kai, de Bruijn, Irene, Chooi, Yit Heng, Coates, R Cameron, Duddela, Srikanth, Edwards, Daniel J, Garg, Neha, Gomez-Escribano, Juan Pablo, Greule, Anja, Haines, Anthony S, Helfrich, Eric J N, Ishida, Keishi, Jones, Adam C, Jones, Carla S, Kegler, Carsten, Kim, Hyun Uk, Kötter, Peter, Masschelein, Joleen, Melnik, Alexey V, Mantovani, Simone M, Monroe, Emily A, Moss, Nathan, Nützmann, Hans-Wilhelm, Pan, Guohui, Reen, F Jerry, Rosconi, Federico, Tian, Zhenhua, Tobias, Nicholas J, Tsunematsu, Yuta, Wiemann, Philipp, Yan, Xiaohui, Xie, Yunchang, Aigle, Bertrand, Apel, Alexander K, Balibar, Carl J, Bechthold, Andreas, Bode, Helge B, Brady, Sean F, Brakhage, Axel A, Caffrey, Patrick, Cheng, Yi-Qiang, Donadio, Stefano, van der Donk, Wilfred A, Doyle, Sean, Driessen, Arnold J M, Entian, Karl-Dieter, Gerwick, Lena, Gerwick, William H, Gross, Harald, Gust, Bertolt, Hertweck, Christian, Ju, Jianhua, Katz, Leonard, Kaysser, Leonard, Klassen, Jonathan L, Keller, Nancy P, Kormanec, Jan, Kuipers, Oscar P, Kuzuyama, Tomohisa, Kyrpides, Nikos C, Kwon, Hyung-Jin, Lavigne, Rob, Lee, Chia Y, Linquan, Bai, Liu, Xinyu, Mahmud, Taifo, Metsä-Ketelä, Mikko, Moore, Bradley S, Moreira, Leonilde M, Müller, Rolf, Neilan, Brett A, O'Gara, Fergal, Oikawa, Hideaki, Osbourn, Anne, Ostash, Bohdan, Payne, Shelley M, Pernodet, Jean-Luc, Piel, Jörn, Raaijmakers, Jos M, Schmitt, Esther K, Scott, Barry, Seipke, Ryan F, Shen, Ben, Sherman, David H, Sosio, Margherita, Stegmann, Evi, Thomas, Christopher M, Tang, Yi, Walton, Jonathan D, Walsh, Christopher T, van Wezel, Gilles P, Wilkinson, Barrie, Wohlleben, Wolfgang, Wright, Gerard D, Ziemert, Nadine, Zhang, Changsheng

“…A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters…”
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A conserved motif flags acyl carrier proteins for [beta]-branching in polyketide synthesis by Haines, Anthony S, Dong, Xu, Song, Zhongshu, Farmer, Rohit, Williams, Christopher, Hothersall, Joanne, Ploskon, Eliza, Wattana-amorn, Pakorn, Stephens, Elton R, Yamada, Erika, Gurney, Rachel, Takebayashi, Yuiko, Masschelein, Joleen, Cox, Russell J, Lavigne, Rob, Willis, Christine L, Simpson, Thomas J, Crosby, John, Winn, Peter J, Thomas, Christopher M, Crump, Matthew P

“…Type I polyketide synthases often use programmed [beta]-branching, via enzymes of a 'hydroxymethylglutaryl-CoA synthase (HCS) cassette', to incorporate various…”
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Increased Abundance of lncP-1[beta] Plasmids and Mercury Resistance Genes in Mercury-Polluted River Sediments: First Discovery of lncP-1 [beta] Plasmids with a Complex mer Transposon as the Sole Accessory Element[white triangle down] by Smalla, Kornelia, Haines, Anthony S, Jones, Karen, Krögerrecklenfort, Ellen

“…Although it is generally assumed that mobile genetic elements facilitate the adaptation of microbial communities to environmental stresses, environmental data…”
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