Search Results - "Haigh, Robert M"
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New Benzylureas as a Novel Series of Potent, Nonpeptidic Vasopressin V2 Receptor Agonists
Published in Journal of medicinal chemistry (25-12-2008)“…Vasopressin (AVP) is a hormone that stimulates an increase in water permeability through activation of V2 receptors in the kidney. The analogue of AVP,…”
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Non-peptide oxytocin agonists
Published in Bioorganic & medicinal chemistry letters (06-09-2004)“…A library of compounds targeted to the vasopressin/oxytocin family of receptors was screened for activity at a cloned human oxytocin receptor using a reporter…”
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Unexpected contractile response from the G-protein activator mastoparan in cardiac myocytes
Published in European journal of pharmacology (15-11-1993)“…Mastoparan preferentially activates the G protein Gi in transmembrane signalling pathways. In heart tissue Gi couples receptors to negative inotropy so we have…”
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Low concentrations of UD-CG 212 enhance myocyte contractility by an increase in calcium responsiveness in the presence of inorganic phosphate
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-06-1995)“…Recent data show that UD-CG 212 in nanomolar concentrations increases myofibrillar Ca++ responsiveness of chemically skinned cardiac preparations in the…”
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Nonpeptide oxytocin agonists
Published in Drugs of the future (01-04-2006)Get full text
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Hypotensive effects of the angiotensin II antagonist telmisartan in conscious chronically-instrumented transgenic rats
Published in Arzneimittel-Forschung (01-08-1996)“…The effects after oral administration of the angiotensin II antagonist telmisartan (CAS 144701-48-4, BIBR 227) on arterial blood pressure and heart rate of…”
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