The role of chromium supplementation in cardiovascular risk factors: A comprehensive reviews of putative molecular mechanisms

In the recent years, micronutrients play an important role in improving body health with preventing and treating of chronic diseases. Chromium is one of the vital minerals involved in the regulation of insulin action. According to abundant evidences this mineral seems to be an essential factor invol...

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Bibliographic Details
Published in:	Heliyon Vol. 9; no. 9; p. e19826
Main Authors:	Gossa Al-Saadde, Dhiaa lattef, Haider, Ali Murtaza, Ali, Arsalan, Abdu Musad Saleh, Ebraheem, Turki Jalil, Abduladheem, Abdulelah, Furqan M., Romero-Parra, Rosario Mireya, Tayyib, Nahla A., Ramírez-Coronel, Andrés Alexis, Alkhayyat, Ameer S.
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 01-09-2023 Elsevier
Subjects:	Cardiovascular diseases Chromium Hypertension Inflammation Oxidative stress Review Hypertension Chromium Oxidative stress Inflammation Cardiovascular diseases
Online Access:	Get full text
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Summary:	In the recent years, micronutrients play an important role in improving body health with preventing and treating of chronic diseases. Chromium is one of the vital minerals involved in the regulation of insulin action. According to abundant evidences this mineral seems to be an essential factor involved in the reduction of insulin resistance and decreasing the risk of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVDs). Moreover, it has been proposed that Chromium supplementation affects mechanisms involved in blood pressure, lipid metabolism, inflammation, and oxidative stress. For instance, it may affect blood pressure through alteration of the renin-angiotensin system, as well as reducing the angiotensin-converting enzyme activity. Furthermore, Chromium supplementation might help reduce the coronary heart disease rates. This study aims to provide a comprehensive review regarding to the effects of Chromium supplementation on CVDs risk factors with an emphasis on possible molecular mechanisms.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	2405-8440 2405-8440
DOI:	10.1016/j.heliyon.2023.e19826