Search Results - "Hahn, Robert G."
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1
The glycocalyx as a permeability barrier: basic science and clinical evidence
Published in Critical care (London, England) (12-09-2022)“…Abstract Preclinical studies in animals and human clinical trials question whether the endothelial glycocalyx layer is a clinically important permeability…”
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2
Hypovolemia with peripheral edema: What is wrong?
Published in Critical care (London, England) (27-05-2023)“…Fluid normally exchanges freely between the plasma and interstitial space and is returned primarily via the lymphatic system. This balance can be disturbed by…”
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3
Sequential recruitment of body fluid spaces for increasing volumes of crystalloid fluid
Published in Frontiers in physiology (28-08-2024)“…The interstitial space harbours two fluid compartments linked serially to the plasma. This study explores conditions that lead to fluid accumulation in the…”
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4
Volume Kinetics for Infusion Fluids
Published in Anesthesiology (Philadelphia) (01-08-2010)“…Volume kinetics is a method used for analyzing and simulating the distribution and elimination of infusion fluids. Approximately 50 studies describe the…”
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5
Accelerated lymph flow from infusion of crystalloid fluid during general anesthesia
Published in BMC anesthesiology (27-03-2024)“…Kinetic analysis of crystalloid fluid yields a central distribution volume (V ) of the same size as the expected plasma volume (approximately 3 L) except…”
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Co-morbidity associated with development of severe COVID-19 before vaccine availability: a retrospective cohort study in the first pandemic year among the middle-aged and elderly in Jönköping county, Sweden
Published in BMC infectious diseases (14-03-2023)“…In preparation of future pandemics, it is important to recognise population-level determinants associated with development of severe illness before efficient…”
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7
Plasma concentrations of syndecan‐1 are dependent on kidney function
Published in Acta anaesthesiologica Scandinavica (01-07-2021)“…Background Elevated plasma concentrations of syndecan‐1 and heparan sulfate in studies of trauma, sepsis, and major surgery are commonly assumed to indicate…”
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8
Intravenous fluid therapy in the perioperative and critical care setting: Executive summary of the International Fluid Academy (IFA)
Published in Annals of intensive care (24-05-2020)“…Intravenous fluid administration should be considered as any other pharmacological prescription. There are three main indications: resuscitation, replacement,…”
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9
Plasma volume expansion and capillary leakage of 20% albumin in burned patients and volunteers
Published in Critical care (London, England) (05-05-2020)“…Burn injury is associated with a long-standing inflammatory reaction. The use of albumin solutions for plasma volume support is controversial because of…”
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10
Detection of low urine output by measuring urinary biomarkers
Published in BMC nutrition (12-01-2024)“…Urine output < 1 L per 24 h is a clinical warning sign that requires attention from hospital staff, who should determine whether the low flow is due to low…”
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11
Volume kinetic analysis of fluid retention after induction of general anesthesia
Published in BMC anesthesiology (25-04-2020)“…Induction of general anesthesia increases the hemodilution resulting from infusion of crystalloid fluid, which is believed to be due to slower distribution…”
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12
Quantifying the daily intake of water from morning and spot urine samples; retrospective analysis of a clinical trial in volunteers
Published in BMC nutrition (02-01-2023)“…The hydration status can be indicated by biomarkers in the urine. However, the sensitivity and specificity of single measurements of biomarkers in morning…”
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13
A Randomized, Multicenter, Open-Label, Blinded End Point, Phase 2, Feasibility, Efficacy, and Safety Trial of Preoperative Microvascular Protection in Patients Undergoing Major Abdominal Surgery
Published in Anesthesia and analgesia (01-10-2021)“…The endothelial glycocalyx, a carbohydrate-rich layer coating all endothelial surfaces, plays a fundamental role in the function of microcirculation. The…”
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14
Urinary Analysis of Fluid Retention in the General Population: A Cross-Sectional Study
Published in PloS one (20-10-2016)“…Renal conservation (retention) of fluid might affect the outcome of hospital care and can be indicated by increased urinary concentrations of metabolic waste…”
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15
Effects of vasoactive drugs on crystalloid fluid kinetics in septic sheep
Published in PloS one (23-02-2017)“…Crystalloid fluid and vasoactive drugs are used in the early treatment of sepsis. The purpose of the present study was to examine how these drugs alter plasma…”
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16
Plasma disappearance rate of albumin when infused as a 20% solution
Published in Critical care (London, England) (11-04-2022)“…The transcapillary leakage of albumin is increased by inflammation and major surgery, but whether exogenous albumin also disappears faster is unclear. An…”
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17
Water content of the endothelial glycocalyx layer estimated by volume kinetic analysis
Published in Intensive care medicine experimental (10-07-2020)“…Background The water volume of the endothelial glycocalyx layer has been estimated at 0.7 to 1.7 L using tracer methods of unclear value. The present study…”
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18
Thirst in heart failure: a systematic literature review
Published in European journal of heart failure (01-02-2013)“…Aims Although patients with heart failure (HF) may suffer from severe thirst, this has received little attention in scientific studies. A systematic literature…”
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Diuretic response to Ringer's solution is normal shortly after awakening from general anaesthesia: a retrospective kinetic analysis
Published in BJA open (01-06-2022)“…The elimination of Ringer's solution is severely depressed during general anaesthesia, but the degree to which this continues postoperatively is poorly…”
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20
Distribution of crystalloid fluid infused during onset of anesthesia-induced hypotension: a retrospective population kinetic analysis
Published in Perioperative medicine (London) (11-10-2021)“…Abstract Background Induction of anesthesia causes a drop in arterial pressure that might change the kinetics of infused crystalloid fluid. The aim of this…”
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