Search Results - "Hagstrom, Kirsten A"
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An SMC-like protein binds and regulates Caenorhabditis elegans condensins
Published in PLoS genetics (16-03-2017)“…Structural Maintenance of Chromosomes (SMC) family proteins participate in multisubunit complexes that govern chromosome structure and dynamics. SMC-containing…”
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Chromosome-biased binding and gene regulation by the Caenorhabditis elegans DRM complex
Published in PLoS genetics (01-05-2011)“…DRM is a conserved transcription factor complex that includes E2F/DP and pRB family proteins and plays important roles in development and cancer. Here we…”
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3
C. elegans condensin promotes mitotic chromosome architecture, centromere organization, and sister chromatid segregation during mitosis and meiosis
Published in Genes & development (15-03-2002)“…Chromosome segregation and X-chromosome gene regulation in Caenorhabditis elegans share the component MIX-1, a mitotic protein that also represses X-linked…”
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A Highly Efficient Multifunctional Tandem Affinity Purification Approach Applicable to Diverse Organisms
Published in Molecular & cellular proteomics (01-08-2012)“…Determining the localization, binding partners, and secondary modifications of individual proteins is crucial for understanding protein function. Several tags…”
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5
Gene Regulation: Silencing Complexes Spread Out
Published in Current biology (17-11-2009)“…Some protein complexes bind DNA elements and then spread to exert gene regulation over broad domains. The Caenorhabditis elegans dosage compensation complex is…”
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Condensin and cohesin: more than chromosome compactor and glue
Published in Nature reviews. Genetics (01-07-2003)“…Two related protein complexes, cohesin and condensin, are essential for separating identical copies of the genome into daughter cells during cell division…”
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Opposing activities of DRM and MES-4 tune gene expression and X-chromosome repression in Caenorhabditis elegans germ cells
Published in G3 : genes - genomes - genetics (10-01-2014)“…During animal development, gene transcription is tuned to tissue-appropriate levels. Here we uncover antagonistic regulation of transcript levels in the…”
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Chromosome-Biased Binding and Gene Regulation by the Caenorhabditis elegans DRM Complex: e1002074
Published in PLoS genetics (01-05-2011)“…DRM is a conserved transcription factor complex that includes E2F/DP and pRB family proteins and plays important roles in development and cancer. Here we…”
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Journal Article