Search Results - "Haglund, L"

Acute mechanical injury of the human intervertebral disc: link to degeneration and pain by Alkhatib, B, Rosenzweig, D H, Krock, E, Roughley, P J, Beckman, L, Steffen, T, Weber, M H, Ouellet, J A, Haglund, L

“…Excessive mechanical loading or acute trauma to intervertebral discs (IVDs) is thought to contribute to degeneration and pain. However, the exact mechanisms by…”
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Thermoreversible hyaluronan-hydrogel and autologous nucleus pulposus cell delivery regenerates human intervertebral discs in an ex vivo, physiological organ culture model by Rosenzweig, D H, Fairag, R, Mathieu, A P, Li, L, Eglin, D, D'Este, M, Steffen, T, Weber, M H, Ouellet, J A, Haglund, L

“…Numerous studies show promise for cell-based tissue engineering strategies aiming to repair painful intervertebral disc (IVD) degeneration. However, clinical…”
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For whom the disc tolls: intervertebral disc degeneration, back pain and toll-like receptors by Bisson, D G, Mannarino, M, Racine, R, Haglund, L

“…Intervertebral disc (IVD) degeneration is characterised by catabolic and inflammatory processes that contribute largely to tissue degradation and chronic back…”
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Differential regulation of TRP channel gene and protein expression by intervertebral disc degeneration and back pain by Sadowska, A., Hitzl, W., Karol, A., Jaszczuk, P., Cherif, H., Haglund, L., Hausmann, O. N., Wuertz-Kozak, K.

“…Intervertebral disc (IVD) degeneration and consequent low back pain (LBP) are common and costly pathological processes that require improved treatment…”
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Axial rotation and pain are associated with facet joint osteoarthritis in adolescent idiopathic scoliosis by Bisson, D.G., Sheng, K., Kocabas, S., Ocay, D.D., Ferland, C.E., Saran, N., Ouellet, J.A., Haglund, L.

“…Facet joints are crucial for spinal stability but develop premature osteoarthritis in patients with adolescent idiopathic scoliosis (AIS). Here, we evaluated…”
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Comparative analysis in continuous expansion of bovine and human primary nucleus pulposus cells for tissue repair applications by Rosenzweig, D H, Tremblay Gravel, J, Bisson, D, Ouellet, J A, Weber, M H, Haglund, L

“…Autologous NP cell implantation is a potential therapeutic avenue for intervertebral disc (IVD) degeneration. However, monolayer expansion of cells isolated…”
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Dynamic loading, matrix maintenance and cell injection therapy of human intervertebral discs cultured in a bioreactor by Rosenzweig, D H, Gawri, R, Moir, J, Beckman, L, Eglin, D, Steffen, T, Roughley, P J, Ouellet, J A, Haglund, L

“…Low back pain originating from intervertebral disc (IVD) degeneration affects the quality of life for millions of people, and it is a major contributor to…”
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Best paper NASS 2013: link-N can stimulate proteoglycan synthesis in the degenerated human intervertebral discs by Gawri, Rahul, Antoniou, John, Ouellet, Jean, Awwad, Waleed, Steffen, Thomas, Roughley, Peter, Haglund, Lisbet, Mwale, Fackson

“…Intervertebral disc (IVD) degeneration is the most common cause of back pain. Presently there is no medical treatment, leaving surgery as the only offered…”
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Chondroadherin prevents bone loss and inhibits tumor growth in animal models of osteoporosis and cancer-induced bone disease by Rucci, N, Capulli, M, Olstad, O.K, Gautvik, K.M, Haglund, L, Heinegård, D, Teti, A

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Large Differences in the Fraction of Active Bacteria in Plankton, Sediments, and Biofilm by HAGLUND, A.-L, TÖRNBLOM, E, BOSTRÖM, B, TRANVIK, L

“…Generally, only a small fraction of free-living pelagic bacteria are metabolically active, while particle-associated bacteria usually exhibit a larger…”
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A new therapeutic approach to prevent oestrogen-withdrawal induced bone loss by Capulli, M, Rufo, A, Capannolo, M, Alamanou, M, Kristoffer, O, Gautvik, K.M, Haglund, L, Heinegård, D, Teti, A, Rucci, N

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The integrin binding domain of chondroadherin is a potential new target for drug development to treat bone metastases, affecting the players of the vicious cycle by Capulli, M, Rufo, A, Alamanou, M, Kristoffer, O, Gautvik, K.M, Haglund, L, Heinegård, D, Teti, A, Rucci, N

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Hand function in women and men with early rheumatoid arthritis. A prospective study over three years (the Swedish TIRA project) by Björk, M., Thyberg, I., Haglund, L., Skogh, T.

“…Objective: To describe the course of hand function in women and men during the first 3 years after diagnosis of recent-onset rheumatoid arthritis (RA), to…”
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220 ANALYSIS OF THE SECRETOME OF HUMAN ARTICULAR CHONDROCYTES INDUCED BY ACTIVATION OF TOLL-LIKE RECEPTOR 2 by Haglund, L, Phelep, A, Heathfield, T, Önnerfjord, P, Dahlberg, L, Recklies, A

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Functional status and quality of life in patients with first-episode major depression by SKÄRSÄTER, I., BAIGI, A., HAGLUND, L.

“…The aim of this study was to analyse the level of severity of major depression and its relation to functioning and health‐related quality of life over time in…”
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Simultaneous radioassays of bacterial production and mercury methylation in the periphyton of a tropical and a temperate wetland by Guimarães, J.R.D., Mauro, J.B.N., Meili, M., Sundbom, M., Haglund, A.L., Coelho-Souza, S.A., Hylander, L.D.

“…Laboratory radioassays were made to study mercury (Hg) methylation together with bacterial production in the periphyton of two aquatic macrophytes, the…”
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Passive transfer of fibromyalgia symptoms from patients to mice by Goebel, Andreas, Krock, Emerson, Gentry, Clive, Israel, Mathilde R, Jurczak, Alexandra, Urbina, Carlos Morado, Sandor, Katalin, Vastani, Nisha, Maurer, Margot, Cuhadar, Ulku, Sensi, Serena, Nomura, Yuki, Menezes, Joana, Baharpoor, Azar, Brieskorn, Louisa, Sandstrom, Angelica, Tour, Jeanette, Kadetoff, Diana, Haglund, Lisbet, Kosek, Eva, Bevan, Stuart, Svensson, Camilla I, Andersson, David A

“…Fibromyalgia syndrome (FMS) is characterized by widespread pain and tenderness, and patients typically experience fatigue and emotional distress. The etiology…”
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Development of a whole disc organ culture system to study human intervertebral disc by Parolin, M, Gawri, R, Mwale, F, Steffen, T, Roughley, P, Antoniou, J, Jarzem, P, Haglund, L, Ouellet, J

“…Basic science Objective:  Low back pain is one of the most common health problems1 and is strongly associated with intervertebral disc degeneration, (IVD)…”
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Patient and public involvement in oesophageal cancer survivorship research by Schandl, Anna, Mälberg, Kalle, Haglund, Lena, Arnberg, Lars, Lagergren, Pernilla

“…Good clinical research is often conducted in close collaboration between patients, the public, and researchers. Few studies have reported the development of…”
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Fibromyalgia patients with elevated levels of anti–satellite glia cell immunoglobulin G antibodies present with more severe symptoms by Krock, Emerson, Morado-Urbina, Carlos E., Menezes, Joana, Hunt, Matthew A., Sandström, Angelica, Kadetoff, Diana, Tour, Jeanette, Verma, Vivek, Kultima, Kim, Haglund, Lisbet, Meloto, Carolina B., Diatchenko, Luda, Kosek, Eva, Svensson, Camilla I.

“…Transferring fibromyalgia patient immunoglobulin G (IgG) to mice induces pain-like behaviour, and fibromyalgia IgG binds mouse and human satellite glia cells…”
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