Search Results - "Hagiwara, Naho"
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Pseudoirreversible inhibition elicits persistent efficacy of a sphingosine 1-phosphate receptor 1 antagonist
Published in Nature communications (19-07-2024)“…Sphingosine 1-phosphate receptor 1 (S1PR1), a G protein-coupled receptor, is required for lymphocyte trafficking, and is a promising therapeutic target in…”
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Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidative stress and autoimmunity
Published in Nature communications (01-02-2024)“…Autophagy is primarily activated by cellular stress, such as starvation or mitochondrial damage. However, stress-independent autophagy is activated by unclear…”
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Acute irradiation causes a long-term disturbance in the heterogeneity and gene expression profile of medullary thymic epithelial cells
Published in Frontiers in immunology (2023)“…The thymus has the ability to regenerate from acute injury caused by radiation, infection, and stressors. In addition to thymocytes, thymic epithelial cells in…”
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Establishing a method for the cryopreservation of viable peripheral blood mononuclear cells in the International Space Station
Published in NPJ microgravity (09-08-2024)“…The analysis of cells frozen within the International Space Station (ISS) will provide crucial insights into the impact of the space environment on cellular…”
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T‐cell receptor repertoire analysis of CD4 ‐positive T cells from blood and an affected organ in an autoimmune mouse model
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-12-2023)“…Abstract One hallmark of some autoimmune diseases is the variability of symptoms among individuals. Organs affected by the disease differ between patients,…”
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