Search Results - "Hagimola, Lejla"

Thromboinflammation Model-on-A-Chip by Whole Blood Microfluidics on Fixed Human Endothelium by Dupuy, Alexander, Hagimola, Lejla, Mgaieth, Neil S A, Houlahan, Callum B, Preketes-Tardiani, Renee E, Coleman, Paul R, Passam, Freda H

“…Microfluidic devices have an established role in the study of platelets and coagulation factors in thrombosis, with potential diagnostic applications. However,…”
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Integrating Phenotypic and Chemoproteomic Approaches to Identify Covalent Targets of Dietary Electrophiles in Platelets by Guan, Ivy A., Liu, Joanna S. T., Sawyer, Renata C., Li, Xiang, Jiao, Wanting, Jiramongkol, Yannasittha, White, Mark D., Hagimola, Lejla, Passam, Freda H., Tran, Denise P., Liu, Xiaoming, Schoenwaelder, Simone M., Jackson, Shaun P., Payne, Richard J., Liu, Xuyu

“…A large variety of dietary phytochemicals has been shown to improve thrombosis and stroke outcomes in preclinical studies. Many of these compounds feature…”
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Protein Disulphide Isomerase 6 (PDIA6) Attenuates Platelet Endoplasmic Reticulum Stress and Secretion in a Mouse Model by Passam, Freda H., Lay, Angelina, Dupuy, Alexander, Tieng, Jessica, Hagimola, Lejla, Maclean, Jessica, Ellis, Marc, Hogg, Philip

“…Background: Platelet hyperreactivity involves increased secretion of their granule content which promotes platelet aggregation and thrombosis. Platelet…”
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Endoplasmic reticulum protein 5 attenuates platelet endoplasmic reticulum stress and secretion in a mouse model by Lay, Angelina J., Dupuy, Alexander, Hagimola, Lejla, Tieng, Jessica, Larance, Mark, Zhang, Yunwei, Yang, Jean, Kong, Yvonne, Chiu, Joyce, Gray, Emilia, Qin, Zihao, Schmidt, Diana, Maclean, Jessica, Hofma, Benjamin, Ellis, Marc, Kalev-Zylinska, Maggie, Argon, Yair, Jackson, Shaun P., Hogg, Philip, Passam, Freda H.

“…•ERp5 inhibits the activation of ER stress sensors protein kinase RNA-like endoplasmic reticulum kinase and IRE1 in murine platelets.•In ERp5-deficient…”
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