Search Results - "Hagerty, Sean W."

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    ESET/SETDB1 Gene Expression and Histone H3 (K9) Trimethylation in Huntington's Disease by Ryu, Hoon, Lee, Junghee, Hagerty, Sean W., Yul Soh, Byoung, McAlpin, Sara E., Cormier, Kerry A., Smith, Karen M., Ferrante, Robert J.

    “…Chromatin remodeling and transcription regulation are tightly controlled under physiological conditions. It has been suggested that altered chromatin…”
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  2. 2

    Modulation of nucleosome dynamics in Huntington's disease by Stack, Edward C., Del Signore, Steven J., Luthi-Carter, Ruth, Soh, Byoung Y., Goldstein, Darlene R., Matson, Samantha, Goodrich, Sarah, Markey, Angela L., Cormier, Kerry, Hagerty, Sean W., Smith, Karen, Ryu, Hoon, Ferrante, Robert J.

    Published in Human molecular genetics (15-05-2007)
    “…Transcriptional dysregulation and aberrant chromatin remodeling are central features in the pathology of Huntington's disease (HD). In order to more fully…”
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    Dose ranging and efficacy study of high-dose coenzyme Q 10 formulations in Huntington's disease mice by Smith, Karen M., Matson, Samantha, Matson, Wayne R., Cormier, Kerry, Del Signore, Steven J., Hagerty, Sean W., Stack, Edward C., Ryu, Hoon, Ferrante, Robert J.

    “…There is substantial evidence that a bioenergetic defect may play a role in the pathogenesis of Huntington's Disease (HD). A potential therapy for remediating…”
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    Dose ranging and efficacy study of high-dose coenzyme Q10 formulations in Huntington's disease mice by Smith, Karen M, Matson, Samantha, Matson, Wayne R, Cormier, Kerry, Del Signore, Steven J, Hagerty, Sean W, Stack, Edward C, Ryu, Hoon, Ferrante, Robert J

    Published in Biochimica et biophysica acta (01-06-2006)
    “…There is substantial evidence that a bioenergetic defect may play a role in the pathogenesis of Huntington's Disease (HD). A potential therapy for remediating…”
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    Journal Article
  8. 8

    Combination therapy using minocycline and coenzyme Q10 in R6/2 transgenic Huntington's disease mice by Stack, Edward C, Smith, Karen M, Ryu, Hoon, Cormier, Kerry, Chen, Minghua, Hagerty, Sean W, Del Signore, Steven J, Cudkowicz, Merit E, Friedlander, Robert M, Ferrante, Robert J

    Published in Biochimica et biophysica acta (01-03-2006)
    “…Huntington's disease (HD) is a fatal neurodegenerative disorder of genetic origin with no known therapeutic intervention that can slow or halt disease…”
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    Journal Article