Search Results - "Hagen, Susan"

Utility of synthetic electrospun fiber matrix in general surgery: From head to toe by Hagen, Susan S.

“…To highlight the role of a novel synthetic electrospun fiber matrix in the treatment of high-risk wounds across a range of etiologies. This was a retrospective…”
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Gastroduodenal injury and repair mechanisms by Hagen, Susan J

“…Although the mucosal barrier serves as a primary interface between the environment and host, little is known about the repair of acute, superficial lesions or…”
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Pathophysiology updates: gastroduodenal injury and repair mechanisms by Hagen, Susan J.

“…Although the mucosal barrier serves as a primary interface between the environment and host, little is known about the repair of acute, superficial lesions or…”
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Gastroduodenal injury and repair: novel targets for therapeutic intervention by Hagen, Susan J.

“…Although the mucosal barrier serves as a primary interface between the environment and host, little is understood about the repair of acute, superficial…”
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Mucosal defense: gastroduodenal injury and repair mechanisms by Hagen, Susan J.

“…PURPOSE OF REVIEWThe mucosal barrier serves as a primary interface between the environment and host. In daily life, superficial injury to the gastric or…”
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Non-canonical functions of claudin proteins: Beyond the regulation of cell-cell adhesions by Hagen, Susan J.

“…Tight junctions form a barrier to the diffusion of apical and basolateral membrane proteins thus regulating membrane polarity. They also regulate the…”
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Do Ulcers Heal Structurally and Functionally? by Hagen, Susan J.

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Paneth cells as a site of origin for intestinal inflammation by Adolph, Timon E., Tomczak, Michal F., Niederreiter, Lukas, Ko, Hyun-Jeong, Böck, Janne, Martinez-Naves, Eduardo, Glickman, Jonathan N., Tschurtschenthaler, Markus, Hartwig, John, Hosomi, Shuhei, Flak, Magdalena B., Cusick, Jennifer L., Kohno, Kenji, Iwawaki, Takao, Billmann-Born, Susanne, Raine, Tim, Bharti, Richa, Lucius, Ralph, Kweon, Mi-Na, Marciniak, Stefan J., Choi, Augustine, Hagen, Susan J., Schreiber, Stefan, Rosenstiel, Philip, Kaser, Arthur, Blumberg, Richard S.

“…Variation in ATG16L1, a protein involved in autophagy, confers risk for Crohn’s disease, but mice with hypomorphic ATG16L1 activity do not develop spontaneous…”
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Loss of Tight Junction Protein Claudin 18 Promotes Progressive Neoplasia Development in Mouse Stomach by Hagen, Susan J., Ang, Lay-Hong, Zheng, Yi, Karahan, Salih N., Wu, Jessica, Wang, Yaoyu E., Caron, Tyler J., Gad, Aniket P., Muthupalani, Sureshkumar, Fox, James G.

“…Loss of claudin 18 (CLDN18), a membrane-spanning tight junction protein, occurs during early stages of development of gastric cancer and associates with…”
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Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier by Caron, Tyler J, Scott, Kathleen E, Fox, James G, Hagen, Susan J

“…Long-term chronic infection with Helicobacter pylori(H. pylori) is a risk factor for gastric cancer development. In the multi-step process that leads to…”
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Neuroendocrine mechanism of gastric acid secretion: Historical perspectives and recent developments in physiology and pharmacology by Chen, Duan, Hagen, Susan J, Boyce, Malcolm, Zhao, Chun-Mei

“…The physiology of gastric acid secretion is one of the earliest subjects in medical literature and has been continuously studied since 1833. Starting with the…”
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Patient-derived enteroids provide a platform for the development of therapeutic approaches in microvillus inclusion disease by Kalashyan, Meri, Raghunathan, Krishnan, Oller, Haley, Bayer, Marie-Theres, Jimenez, Lissette, Roland, Joseph T, Kolobova, Elena, Hagen, Susan J, Goldsmith, Jeffrey D, Shub, Mitchell D, Goldenring, James R, Kaji, Izumi, Thiagarajah, Jay R

“…Microvillus inclusion disease (MVID), caused by loss-of-function mutations in the motor protein myosin Vb (MYO5B), is a severe infantile disease characterized…”
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Unraveling a New Role for Claudins in Gastric Tumorigenesis by Hagen, Susan J., PhD

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Regulation of intestinal epithelial intercellular adhesion and barrier function by desmosomal cadherin desmocollin-2 by Raya-Sandino, Arturo, Luissint, Anny-Claude, Kusters, Dennis H M, Narayanan, Vani, Flemming, Sven, Garcia-Hernandez, Vicky, Godsel, Lisa M, Green, Kathleen J, Hagen, Susan J, Conway, Daniel E, Parkos, Charles A, Nusrat, Asma

“…The role of desmosomal cadherin desmocollin-2 (Dsc2) in regulating barrier function in intestinal epithelial cells (IECs) is not well understood. Here, we…”
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Muc5ac null mice are predisposed to spontaneous gastric antro-pyloric hyperplasia and adenomas coupled with attenuated H. pylori-induced corpus mucous metaplasia by Muthupalani, Sureshkumar, Ge, Zhongming, Joy, Joanna, Feng, Yan, Dobey, Carrie, Cho, Hye-Youn, Langenbach, Robert, Wang, Timothy C, Hagen, Susan J, Fox, James G

“…Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide and is strongly associated with chronic Helicobacter pylori (Hp) infection…”
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Acyl-CoA thioesterase 12 suppresses YAP-mediated hepatocarcinogenesis by limiting glycerolipid biosynthesis by He, Haiyue, Sugiyama, Akiko, Snyder, Nathaniel W., Teneche, Marcos G., Liu, Xiaowei, Maner-Smith, Kristal M., Goessling, Wolfram, Hagen, Susan J., Ortlund, Eric A., Najafi-Shoushtari, S. Hani, Acuña, Mariana, Cohen, David E.

“…Cancer cells use acetate to support the higher demand for energy and lipid biosynthesis during uncontrolled cell proliferation, as well as for acetylation of…”
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Allosteric regulation of thioesterase superfamily member 1 by lipid sensor domain binding fatty acids and lysophosphatidylcholine by Tillman, Matthew C., Imai, Norihiro, Li, Yue, Khadka, Manoj, Okafor, C. Denise, Juneja, Puneet, Adhiyaman, Akshitha, Hagen, Susan J., Cohen, David E., Ortlund, Eric A.

“…Nonshivering thermogenesis occurs in brown adipose tissue to generate heat in response to cold ambient temperatures. Thioesterase superfamily member 1 (Them1)…”
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Thioesterase superfamily member 1 undergoes stimulus-coupled conformational reorganization to regulate metabolism in mice by Li, Yue, Imai, Norihiro, Nicholls, Hayley T., Roberts, Blaine R., Goyal, Samaksh, Krisko, Tibor I., Ang, Lay-Hong, Tillman, Matthew C., Roberts, Anne M., Baqai, Mahnoor, Ortlund, Eric A., Cohen, David E., Hagen, Susan J.

“…In brown adipose tissue, thermogenesis is suppressed by thioesterase superfamily member 1 (Them1), a long chain fatty acyl-CoA thioesterase. Them1 is highly…”
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Presenteeism: Critical Issues by Brooks, Ambyr, Hagen, Susan E., Sathyanarayanan, Sudhakar, Schultz, Alyssa B., Edington, Dee W.

“…Objective: The objective of this commentary is to discuss the issues surrounding the concept of presenteeism, including the measurement of lost work time per…”
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Synthesis of CID-cleavable protein crosslinking agents containing quaternary amines for structural mass spectrometry by Hagen, Susan E, Liu, Kun, Jin, Yafei, Piersimoni, Lolita, Andrews, Philip C, Showalter, Hollis D

“…Two novel cyclic quaternary amine crosslinking probes are synthesized for structural mass spectrometry of protein complexes in solution and for analysis of…”
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