Search Results - "Hagen, Jason L."

Skeletal Muscle Aging in F344BN F1-Hybrid Rats: I. Mitochondrial Dysfunction Contributes to the Age-Associated Reduction in VO2max by Hagen, Jason L., Krause, Daniel J., Baker, David J., Fu, Ming Hua, Tarnopolsky, Mark A., Hepple, Russell T.

“…Although mitochondrial DNA damage accumulates in aging skeletal muscles, how this relates to the decline in muscle mass-specific skeletal muscle aerobic…”
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Skeletal Muscle Aging in F344BN F1-Hybrid Rats: II. Improved Contractile Economy in Senescence Helps Compensate for Reduced ATP-Generating Capacity by Hepple, Russell T., Hagen, Jason L., Krause, Daniel J., Baker, David J.

“…We used a pump-perfused rat hind-limb preparation to compare young adult (YA: 8–9- month-old), late middle-aged (LMA: 28–29-month-old), and senescent (SEN:…”
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Oxidative capacity interacts with oxygen delivery to determine maximal O2 uptake in rat skeletal muscles in situ by Hepple, Russell T., Hagen, Jason L., Krause, Dan J.

“…Based on proportional changes in V̇ O 2 ,max with alterations in O 2 delivery, it is widely held that O 2 availability limits V̇ O 2 ,max . In contrast,…”
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Nitric oxide synthase inhibition reduces the O2 cost of force development in rat hindlimb muscles pump perfused at matched convective O2 delivery by Krause, Daniel J., Hagen, Jason L., Kindig, Casey A., Hepple, Russell T.

“…Nitric oxide (NO) is a physiological mediator of skeletal muscle function. Specifically, NO affects cellular respiration and muscle contractility; however, the…”
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Aerobic power declines with aging in rat skeletal muscles perfused at matched convective O2 delivery by Hepple, Russell T, Hagen, Jason L, Krause, Daniel J, Jackson, Cory C

“…1  Faculty of Kinesiology and 2  Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 1N4 Although it is well established that maximal O 2…”
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Aerobic power declines with aging in rat skeletal muscles perfused at matched convective O 2 delivery by Hepple, Russell T., Hagen, Jason L., Krause, Daniel J., Jackson, Cory C.

“…Although it is well established that maximal O 2 uptake (V˙o 2 max ) declines from adulthood to old age, the role played by alterations in skeletal muscle is…”
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Oxidative capacity interacts with oxygen delivery to determine maximal O 2 uptake in rat skeletal muscles in situ by Hepple, Russell T., Hagen, Jason L., Krause, Dan J.

“…Based on proportional changes in V̇ O2,max with alterations in O 2 delivery, it is widely held that O 2 availability limits V̇ O2,max . In contrast, reductions…”
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Skeletal Muscle Aging in F344BN F1-Hybrid Rats: I. Mitochondrial Dysfunction Contributes to the Age-Associated Reduction in VO^sub 2max by Hagen, Jason L, Krause, Daniel J, Baker, David J, Fu, Ming Hua

“…Although mitochondrial DNA damage accumulates in aging skeletal muscles, how this relates to the decline in muscle mass-specific skeletal muscle aerobic…”
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Oxidative capacity interacts with oxygen delivery to determine maximal O(2) uptake in rat skeletal muscles in situ by Hepple, Russell T, Hagen, Jason L, Krause, Dan J

“…Based on proportional changes in V(O(2))(,max) with alterations in O(2) delivery, it is widely held that O(2) availability limits V(O(2))(,max). In contrast,…”
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Nitric oxide synthase inhibition reduces the O sub(2) cost of force development in rat hindlimb muscles pump perfused at matched convective O sub(2) delivery by Krause, Daniel J, Hagen, Jason L, Kindig, Casey A, Hepple, Russell T

“…Nitric oxide (NO) is a physiological mediator of skeletal muscle function. Specifically, NO affects cellular respiration and muscle contractility; however, the…”
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Experimental Physiology: Nitric oxide synthase inhibition reduces the O2 cost of force development in rat hindlimb muscles pump perfused at matched convective O2 delivery by Krause, Daniel J, Hagen, Jason L, Kindig, Casey A, Hepple, Russell T

“…Nitric oxide (NO) is a physiological mediator of skeletal muscle function. Specifically, NO affects cellular respiration and muscle contractility; however, the…”
Get full text

Nitric oxide synthase inhibition reduces the O 2 cost of force development in rat hindlimb muscles pump perfused at matched convective O 2 delivery by Krause, Daniel J., Hagen, Jason L., Kindig, Casey A., Hepple, Russell T.

“…Nitric oxide (NO) is a physiological mediator of skeletal muscle function. Specifically, NO affects cellular respiration and muscle contractility; however, the…”
Get full text

V̇ o 2 max is unaffected by altering the temporal pattern of stimulation frequency in rat hindlimb in situ by Hepple, Russell T., Krause, Daniel J., Hagen, Jason L., Jackson, Cory C.

“…It might be anticipated that fatiguing contractions would impair the aerobic metabolic response in skeletal muscle if significant fatigue developed before full…”
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V(O2) max is unaffected by altering the temporal pattern of stimulation frequency in rat hindlimb in situ by Hepple, Russell T, Krause, Daniel J, Hagen, Jason L, Jackson, Cory C

“…It might be anticipated that fatiguing contractions would impair the aerobic metabolic response in skeletal muscle if significant fatigue developed before full…”
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VO2 max is unaffected by altering the temporal pattern of stimulation frequency in rat hindlimb in situ by Hepple, Russell T, Krause, Daniel J, Hagen, Jason L, Jackson, Cory C

“…1 Faculty of Kinesiology and 2 Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 1N4 Submitted 21 January 2003 ; accepted in final form…”
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Vo2max is unaffected by altering the temporal pattern of stimulation frequency in rat hindlimb in situ by Hepple, Russell T, Krause, Daniel J, Hagen, Jason L, Jackson, Cory C

“…It might be anticipated that fatiguing contractions would impair the aerobic metabolic response in skeletal muscle if significant fatigue developed before full…”
Get full text