Search Results - "Hagen, Fred"
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Bladder cancer exosomes contain EDIL-3/Del1 and facilitate cancer progression
Published in The Journal of urology (01-08-2014)“…High grade bladder cancer is an extremely aggressive malignancy associated with high rates of morbidity and mortality. Understanding how exosomes may affect…”
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Targeting Aberrant Glutathione Metabolism to Eradicate Human Acute Myelogenous Leukemia Cells
Published in The Journal of biological chemistry (22-11-2013)“…The development of strategies to eradicate primary human acute myelogenous leukemia (AML) cells is a major challenge to the leukemia research field. In…”
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Proteomic Analysis of Human Parotid Gland Exosomes by Multidimensional Protein Identification Technology (MudPIT)
Published in Journal of proteome research (06-03-2009)“…Human ductal saliva contributes over a thousand unique proteins to whole oral fluids. The mechanism by which most of these proteins are secreted by salivary…”
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Modification of Streptococcus mutans Cnm by PgfS Contributes to Adhesion, Endothelial Cell Invasion, and Virulence
Published in Journal of bacteriology (01-08-2014)“…Expression of the surface protein Cnm has been directly implicated in the ability of certain strains of Streptococcus mutans to bind to collagen and to invade…”
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Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells
Published in The Journal of biological chemistry (14-10-2016)“…Although multidrug approaches to cancer therapy are common, few strategies are based on rigorous scientific principles. Rather, drug combinations are largely…”
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Mitochondrially targeted nitro‐linoleate: a new tool for the study of cardioprotection
Published in British journal of pharmacology (01-04-2014)“…Background and Purpose Cardiac ischaemia–reperfusion (IR) injury remains a significant clinical problem with limited treatment options available. We previously…”
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Initiation of Protein O Glycosylation by the Polypeptide GalNAcT-1 in Vascular Biology and Humoral Immunity
Published in Molecular and Cellular Biology (01-12-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Melampomagnolide B: A new antileukemic sesquiterpene
Published in Bioorganic & medicinal chemistry (15-02-2011)“…Melampomagnolide B (3) has been identified as a new antileukemic sesquiterpene. A biotin-conjugated derivative (4) of melampomagnolide B was designed and…”
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Aspirin acetylates multiple cellular proteins in HCT-116 colon cancer cells: Identification of novel targets
Published in International journal of oncology (01-11-2011)“…Epidemiological and clinical observations provide consistent evidence that regular intake of aspirin may effectively inhibit the occurrence of epithelial…”
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Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells
Published in The Journal of biological chemistry (25-11-2016)Get full text
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11
Quantitative Analysis of Age Specific Variation in the Abundance of Human Female Parotid Salivary Proteins
Published in Journal of proteome research (01-11-2009)“…Human saliva is a protein-rich, easily accessible source of potential local and systemic biomarkers to monitor changes that occur under pathological…”
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The human biliverdin reductase-based peptide fragments and biliverdin regulate protein kinase Cδ activity: the peptides are inhibitors or substrate for the protein kinase C
Published in The Journal of biological chemistry (13-07-2012)“…PKCδ, a Ser/Thr kinase, promotes cell growth, tumorigenesis, and apoptosis. Human biliverdin reductase (hBVR), a Ser/Thr/Tyr kinase, inhibits apoptosis by…”
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Systematic comparison of the human saliva and plasma proteomes
Published in Proteomics. Clinical applications (01-01-2009)“…The proteome of human salivary fluid has the potential to open new doors for disease biomarker discovery. A recent study to comprehensively identify and…”
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β-L-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (L-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism
Published in Antiviral research (01-10-2014)“…The alphaherpesvirus varicella-zoster virus (VZV) causes chickenpox and shingles. Current treatments are acyclovir (ACV) and its derivatives, foscarnet and…”
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Human Common Salivary Protein 1 (CSP-1) Promotes Binding of Streptococcus mutans to Experimental Salivary Pellicle and Glucans Formed on Hydroxyapatite Surface
Published in Journal of proteome research (03-12-2010)“…The saliva proteome includes host defense factors and specific bacterial-binding proteins that modulate microbial growth and colonization of the tooth surface…”
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The Proteomes of Human Parotid and Submandibular/Sublingual Gland Salivas Collected as the Ductal Secretions
Published in Journal of proteome research (01-05-2008)“…Saliva is a body fluid with important functions in oral and general health. A consortium of three research groups catalogued the proteins in human saliva…”
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Identification of Membrane-bound Variant of Metalloendopeptidase Neurolysin (EC 3.4.24.16) as the Non-angiotensin Type 1 (Non-AT1), Non-AT2 Angiotensin Binding Site
Published in The Journal of biological chemistry (02-01-2012)“…Recently, we discovered a novel non-angiotensin type 1 (non-AT1), non-AT2 angiotensin binding site in rodent and human brain membranes, which is distinctly…”
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Systematic Analysis of Proteoglycan Modification Sites in Caenorhabditis elegans by Scanning Mutagenesis
Published in The Journal of biological chemistry (11-05-2007)“…Proteoglycan modification is essential for development and early cell division in Caenorhabditis elegans. The specification of proteoglycan attachment sites is…”
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Professor Cees Veeger and the early years of bioinorganic chemistry
Published in The FEBS journal (01-05-2018)Get full text
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The terminal phase of cytokinesis in the Caenorhabditis elegans early embryo requires protein glycosylation
Published in Molecular biology of the cell (01-09-2005)“…RNA interference (RNAi) was used to characterize the requirement of protein glycosylation for cell membrane stability during cytokinesis in the early embryo…”
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