Search Results - "Hagelund, Sofie"

Impact of Extracellular pH on Apoptotic and Non-Apoptotic TRAIL-Induced Signaling in Pancreatic Ductal Adenocarcinoma Cells by Hagelund, Sofie, Trauzold, Anna

“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an important mediator of tumor immune surveillance. In addition, its potential to kill…”
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The Vacuolar H + ATPase α3 Subunit Negatively Regulates Migration and Invasion of Human Pancreatic Ductal Adenocarcinoma Cells by Flinck, Mette, Hagelund, Sofie, Gorbatenko, Andrej, Severin, Marc, Pedraz-Cuesta, Elena, Novak, Ivana, Stock, Christian, Pedersen, Stine Falsig

“…Increased metabolic acid production and upregulation of net acid extrusion render pH homeostasis profoundly dysregulated in many cancers. Plasma membrane…”
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Endogenous TRAIL-R4 critically impacts apoptotic and non-apoptotic TRAIL-induced signaling in cancer cells by Rambow, Anna-Christina, Aschenbach, Insa, Hagelund, Sofie, Tawfik, Doaa, Gundlach, Jan-Paul, Weiße, Sebastian, Maass, Nicolai, Trauzold, Anna

“…Binding of TRAIL to its death domain-containing receptors TRAIL-R1 and TRAIL-R2 can induce cell death and/or pro-inflammatory signaling. The importance of…”
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