Search Results - "Hagan, Nathan A."

Understanding the Isomerization of the HIV-1 Dimerization Initiation Domain by the Nucleocapsid Protein by Turner, Kevin B., Hagan, Nathan A., Fabris, Daniele

“…The specific binding of HIV-1 nucleocapsid (NC) to the hinge region of the kissing-loop (KL) dimer formed by stemloop 1 (SL1) can have significant consequences…”
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Dissecting the Protein–RNA and RNA–RNA Interactions in the Nucleocapsid-mediated Dimerization and Isomerization of HIV-1 Stemloop 1 by Hagan, Nathan A., Fabris, Daniele

“…The specific binding of HIV-1 nucleocapsid protein (NC) to the different forms assumed in vitro by the stemloop 1 (Lai variant) of the genome's packaging…”
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Noncovalent probes for the investigation of structure and dynamics of protein-nucleic acid assemblies: The case of NC-mediated dimerization of genomic RNA in HIV-1 by Turner, Kevin B., Kohlway, Andrew S., Hagan, Nathan A., Fabris, Daniele

“…The nature of specific RNA‐RNA and protein‐RNA interactions involved in the process of genome dimerization and isomerization in HIV‐1, which is mediated in…”
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Enhanced In-Source Fragmentation in MALDI-TOF-MS of Oligonucleotides Using 1,5-Diaminonapthalene by Hagan, Nathan A., Smith, Christine A., Antoine, Miquel D., Lin, Jeffrey S., Feldman, Andrew B., Demirev, Plamen A.

“…The capability to rapidly and confidently determine or confirm the sequences of short oligonucleotides, including native and chemically-modified DNA and RNA,…”
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Mapping Noncovalent Ligand Binding to Stemloop Domains of the HIV-1 Packaging Signal by Tandem Mass Spectrometry by Turner, Kevin B., Hagan, Nathan A., Kohlway, Andrew S., Fabris, Daniele

“…The binding modes and structural determinants of the noncovalent complexes formed by aminoglycoside antibiotics with conserved domains of the HIV-1 packaging…”
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Inhibitory effects of archetypical nucleic acid ligands on the interactions of HIV-1 nucleocapsid protein with elements of Ψ-RNA by Turner, Kevin B., Hagan, Nathan A., Fabris, Daniele

“…Disrupting the interactions between human immunodeficiency virus type 1 (HIV-1) nucleocapsid (NC) protein and structural elements of the packaging signal…”
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Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides by Fisher, Robert J., Fivash, Matthew J., Stephen, Andrew G., Hagan, Nathan A., Shenoy, Shilpa R., Medaglia, Maxine V., Smith, Lindsey R., Worthy, Karen M., Simpson, John T., Shoemaker, Robert, McNitt, Karen L., Johnson, Donald G., Hixson, Catherine V., Gorelick, Robert J., Fabris, Daniele, Henderson, Louis E., Rein, Alan

“…The HIV-1 nucleocapsid (NC) protein is a small, basic protein containing two retroviral zinc fingers. It is a highly active nucleic acid chaperone; because of…”
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Detection and identification of immobilized low-volatility organophosphates by desorption ionization mass spectrometry by Hagan, Nathan A., Cornish, Timothy J., Pilato, Robert S., Van Houten, Kelly A., Antoine, Miquel D., Lippa, Timothy P., Becknell, Alan F., Demirev, Plamen A.

“…Two desorption ionization mass spectrometry (MS) techniques – ultraviolet laser desorption/ionization (LDI) and desorption electrospray ionization (DESI) –…”
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Rapid purification of RNA secondary structures by Gelhaus, Stacy L., LaCourse, William R., Hagan, Nathan A., Amarasinghe, Gaya K., Fabris, Daniele

“…A new method for rapid purification and structural analysis of oligoribonucleotides of 19 and 20 nt is applied to RNA hairpins SL3 and SL2, which are stable…”
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Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides by Fisher, Robert J., Fivash, Matthew J., Stephen, Andrew G., Hagan, Nathan A., Shenoy, Shilpa R., Medaglia, Maxine V., Smith, Lindsey R., Worthy, Karen M., Simpson, John T., Shoemaker, Robert, McNitt, Karen L., Johnson, Donald G., Hixson, Catherine V., Gorelick, Robert J., Fabris, Daniele, Henderson, Louis E., Rein, Alan

“…The HIV-1 nucleocapsid (NC) protein is a small, basic protein containing two retroviral zinc fingers. It is a highly active nucleic acid chaperone; because of…”
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Thermally enhanced enzymatic proteolysis for rapid 18O labeling in proteomics by Antoine, Miquel D., Hagan, Nathan A., Demirev, Plamen A.

“…[Display omitted] ► We streamline protein identification protocols utilizing a microwave oven and a PCR thermocycler to accelerate enzymatic digestion. ►…”
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Rapid detection of ribosome inactivating protein toxins by mass-spectrometry-based functional assays by Antoine, Miquel D., Hagan, Nathan A., Lin, Jeffrey S., Feldman, Andrew B., Demirev, Plamen A.

“…[Display omitted] ► We have developed a rapid functional assay for robust and broad-band detection of protein toxins in powders. ► The assay is based on…”
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Non-covalent probes for the investigation of structure and dynamics of protein-nucleic acid assemblies: the case of NC-mediated dimerization of genomic RNA in HIV-1 by Turner, Kevin B., Kohlway, Andrew S., Hagan, Nathan A., Fabris, Daniele

“…The nature of specific RNA-RNA and protein-RNA interactions involved in the process of genome dimerization and isomerization in HIV-1, which is mediated in…”
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Inhibitory effects of archetypical nucleic acid ligands on the interactions of HIV-1 nucleocapsid protein with elements of  -RNA by Turner, K. B.

“…Disrupting the interactions between human immunodeficiency virus type 1 (HIV-1) nucleocapsid (NC) protein and structural elements of the packaging signal…”
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