Search Results - "Haga, Jason"

Virtual Screening Techniques and Current Computational Infrastructures by Haga, Jason H, Ichikawa, Kohei, Date, Susumu

“…The drug discovery process in general is a very resource intensive undertaking that has existed for a very long time. In the last two decades, performing…”
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Molecular basis of the effects of shear stress on vascular endothelial cells by Li, Yi-Shuan J., Haga, Jason H., Chien, Shu

“…Blood vessels are constantly exposed to hemodynamic forces in the form of cyclic stretch and shear stress due to the pulsatile nature of blood pressure and…”
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Molecular basis of the effects of mechanical stretch on vascular smooth muscle cells by Haga, Jason H, Li, Yi-Shuan J, Chien, Shu

“…Abstract The pulsatile nature of blood pressure and flow creates hemodynamic stimuli in the forms of cyclic stretch and shear stress, which exert continuous…”
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Interactive museum exhibits with embedded systems: A use‐case scenario by Wong, Lok, Shimojo, Shinji, Teranishi, Yuuichi, Yoshihisa, Tomoki, Haga, Jason H.

“…Summary The feasibility of using embedded systems in real‐life applications is becoming more widespread. These applications have grown from do‐it‐yourself…”
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Shear stress regulation of Krüppel-like factor 2 expression is flow pattern-specific by Wang, Nanping, Miao, Hui, Li, Yi-Shuan, Zhang, Peng, Haga, Jason H., Hu, Yingli, Young, Angela, Yuan, Suli, Nguyen, Phu, Wu, Chia-Ching, Chien, Shu

“…Flow patterns in blood vessels contribute to focal distribution of atherosclerosis; the underlying mechanotransduction pathways remain to be investigated. We…”
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Directional shear flow and Rho activation prevent the endothelial cell apoptosis induced by micropatterned anisotropic geometry by Wu, Chia-Ching, Li, Yi-Shuan, Haga, Jason H, Kaunas, Roland, Chiu, Jeng-Jiann, Su, Fong-Chin, Usami, Shunichi, Chien, Shu

“…To study the roles of anisotropic cell morphology and directionality of mechanical force in apoptosis, the spreading of human umbilical vein endothelial cells…”
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Mechanisms of the negative inotropic effects of sphingosine-1-phosphate on adult mouse ventricular myocytes by Landeen, Lee K, Dederko, Dorothy A, Kondo, Colleen S, Hu, Betty S, Aroonsakool, Nakon, Haga, Jason H, Giles, Wayne R

“…Sphingosine-1-phosphate (S1P) induces a transient bradycardia in mammalian hearts through activation of an inwardly rectifying K(+) current (I(K(ACh))) in the…”
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Predicting river water height using deep learning-based features by Borwarnginn, Punyanuch, Haga, Jason H., Kusakunniran, Worapan

“…The paper presents the river height prediction model using real-world historical sensor data such as rainfall, cumulative rainfall, and river water heights…”
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ViewDock TDW: high-throughput visualization of virtual screening results by Lau, Christopher D., Levesque, Marshall J., Chien, Shu, Date, Susumu, Haga, Jason H.

“…ViewDock TDW is a modification of the pre-existing ViewDock Chimera extension (http://www.cgl.ucsf.edu/chimera/) used to visualize results of virtual screening…”
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PRAGMA‐ENT: An International SDN testbed for cyberinfrastructure in the Pacific Rim by Ichikawa, Kohei, U‐Chupala, Pongsakorn, Huang, Che, Nakasan, Chawanat, Liu, Te‐Lung, Chang, Jo‐Yu, Ku, Li‐Chi, Tsai, Whey‐Fone, Haga, Jason, Yamanaka, Hiroaki, Kawai, Eiji, Kido, Yoshiyuki, Date, Susumu, Shimojo, Shinji, Papadopoulos, Philip, Tsugawa, Mauricio, Collins, Matthew, Jeong, Kyuho, Figueiredo, Renato, Fortes, Jose

“…Summary The Pacific Rim Application and Grid Middleware Assembly (PRAGMA) is an international community of researchers that actively collaborate to address…”
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Sphingosine-1-phosphate receptor expression in cardiac fibroblasts is modulated by in vitro culture conditions by Landeen, Lee K, Aroonsakool, Nakon, Haga, Jason H, Hu, Betty S, Giles, Wayne R

“…The bioactive molecule sphingosine-1-phosphate (S1P) binds with high affinity to five recognized receptors (S1P(1-5)) to affect various tissues, including…”
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Design of a grid service-based platform for in silico protein–ligand screenings by Levesque, Marshall J, Ichikawa, Kohei, Date, Susumu, Haga, Jason H

“…Abstract Grid computing offers the powerful alternative of sharing resources on a worldwide scale, across different institutions to run computationally…”
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Roles of MAP kinases in the regulation of bone matrix gene expressions in human osteoblasts by oscillatory fluid flow by Wu, Chia-Ching, Li, Yi-Shuan, Haga, Jason H., Wang, Nanping, Lian, Ian Y-Z., Su, Fong-Chin, Usami, Shunichi, Chien, Shu

“…We investigated the effects of oscillatory flow in regulating the gene expressions of type I collagen (COL1, the main component of human bone tissues) and…”
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Roles of microfilaments and microtubules in paxillin dynamics by Hu, Ying-Li, Haga, Jason H., Miao, Hui, Wang, Yingxiao, Li, Yi-Shuan, Chien, Shu

“…We investigated the roles of microfilaments and microtubules in the localization and tyrosine phosphorylation of paxillin, a focal adhesion-associated…”
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Water Level Detection from CCTV Cameras using a Deep Learning Approach by Borwarnginn, Punyanuch, Haga, Jason H., Kusakunniran, Worapan

“…Natural disasters are a global problem that causes widespread losses and damage. A system to provide timely information is required in order to help reduce…”
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Differential expression of a ligand induced binding site (LIBS) by GPIIb-IIIa ligand recognition peptides and parenteral antagonists by Jennings, L K, Haga, J H, Slack, S M

“…The glycoprotein (GP) IIb-IIIa complex is an attractive anti-platelet target for the prevention of thrombotic events associated with coronary artery disease…”
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DNA microarray study on gene expression profiles in co-cultured endothelial and smooth muscle cells in response to 4- and 24-h shear stress by Heydarkhan-Hagvall, Sepideh, Chien, Shu, Nelander, Sven, Li, Yi-Chen, Yuan, Suli, Lao, Jianmin, Haga, Jason H, Lian, Ian, Nguyen, Phu, Risberg, Bo, Li, Yi-Shuan

“…Shear stress, a major hemodynamic force acting on the vessel wall, plays an important role in physiological processes such as cell growth, differentiation,…”
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Comparison of Shear Stress–Induced Platelet Microparticle Formation and Phosphatidylserine Expression in Presence of αIIbβ3 Antagonists by Haga, Jason H, Slack, Steven M, Jennings, Lisa K

“…The use of platelet glycoprotein IIb-IIIa (αIIbβ3) antagonists is an accepted practice in the treatment of acute coronary syndromes. Recent studies have…”
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Snow Scene Segmentation Using CNN-Based Approach With Transfer Learning by Pooyoi, Parintorn, Borwarnginn, Punyanuch, Haga, Jason H., Kusakunniran, Worapan

“…Images from CCTV cameras can be used for analyzing disaster situations in a particular area. Snowfall is one of the weather conditions that could cause natural…”
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Quantification of the passive mechanical properties of the resting platelet by HAGA, J. H, BEAUDOIN, A. J, WHITE, J. G, STRONY, J

“…Sudden coronary artery occlusion is one of the leading causes of death. Several in vitro models have been used to study the relationship between hemodynamic…”
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