Search Results - "Hagège, Albert A."

Myocardial Infarction Alters Adaptation of the Tethered Mitral Valve by Dal-Bianco, Jacob P., MD, Aikawa, Elena, MD, PhD, Bischoff, Joyce, PhD, Guerrero, J. Luis, BS, Hjortnaes, Jesper, MD, Beaudoin, Jonathan, MD, Szymanski, Catherine, MD, Bartko, Philipp E., MD, PhD, Seybolt, Margo M., BS, Handschumacher, Mark D., BS, Sullivan, Suzanne, BS, Garcia, Michael L., MA, Mauskapf, Adam, BA, Titus, James S., BS, Wylie-Sears, Jill, MS, Irvin, Whitney S., MS, Chaput, Miguel, MD, Messas, Emmanuel, MD, PhD, Hagège, Albert A., MD, PhD, Carpentier, Alain, MD, PhD, Levine, Robert A., MD

“…Abstract Background In patients with myocardial infarction (MI), leaflet tethering by displaced papillary muscles induces mitral regurgitation (MR), which…”
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Transplantation of cardiac-committed mouse embryonic stem cells to infarcted sheep myocardium: a preclinical study by Ménard, Claudine, Hagège, Albert A, Agbulut, Onnik, Barro, Marietta, Morichetti, Miguel Cortes, Brasselet, Camille, Bel, Alain, Messas, Emmanuel, Bissery, Alvine, Bruneval, Patrick, Desnos, Michel, Pucéat, Michel, Menasché, Philippe

“…Heart failure develops after myocardial infarction and is a major cause of morbidity and mortality. The ability to direct differentiation of embryonic stem…”
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Myoblast transplantation for heart failure by Menasché, Philippe, Hagège, Albert A, Scorsin, Marcio, Pouzet, Bruno, Desnos, Michel, Duboc, Denis, Schwartz, Ketty, Vilquin, Jean-Thomas, Marolleau, Jean-Pierre

“…Intramyocardial skeletal muscle transplantation has been shown experimentally to improve heart function after infarction. We report success with this procedure…”
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Viability and differentiation of autologous skeletal myoblast grafts in ischaemic cardiomyopathy by Hagège, Albert A, Carrion, Claire, Menasché, Philippe, Vilquin, Jean-Thomas, Duboc, Denis, Marolleau, Jean-Pierre, Desnos, Michel, Bruneval, Patrick

“…Autologous skeletal myoblast transplantation might improve postinfarction ventricular function, but graft viability and differentiation (ie, proof of concept)…”
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Transplantation of autologous fresh bone marrow into infarcted myocardium: A word of caution by BEL, Alain, MESSAS, Emmanuel, AGBULUT, Onnik, RICHARD, Patrice, SAMUEL, Jane-Lyse, BRUNEVAL, Patrick, HAGEGE, Albert A, MENASCHE

“…As the benefits of extemporaneous transplantation (Tx) of fresh (unfractionated) autologous bone marrow (BM) have been primarily studied in the setting of…”
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Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction by Menasché, Philippe, Hagège, Albert A, Vilquin, Jean-Thomas, Desnos, Michel, Abergel, Eric, Pouzet, Bruno, Bel, Alain, Sarateanu, Sorin, Scorsin, Marcio, Schwartz, Ketty, Bruneval, Patrick, Benbunan, Marc, Marolleau, Jean-Pierre, Duboc, Denis

“…This phase I trial was designed to assess the feasibility and safety of autologous skeletal myoblast transplantation in patients with severe ischemic…”
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Factors affecting functional outcome after autologous skeletal myoblast transplantation by Pouzet, Bruno, Vilquin, Jean-Thomas, Hagège, Albert A, Scorsin, Marcio, Messas, Emmanuel, Fiszman, Marc, Schwartz, Ketty, Menasché, Philippe

“…Background. This study assessed the extent to which the initial degree of functional impairment and the number of injected cells may influence the functional…”
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Does the functional efficacy of skeletal myoblast transplantation extend to nonischemic cardiomyopathy? by POULY, Julia, HAGEGE, Albert A, MENASCHE, Philippe, VILQUIN, Jean-Thomas, BISSERY, Alvine, ROUCHE, Andrée, BRUNEVAL, Patrick, DUBOC, Denis, DESNOS, Michel, FISZMAN, Marc, FROMES, Yves

“…The benefits of skeletal myoblast (SM) transplantation on infarcted myocardium have been investigated extensively; however, little is known about its effects…”
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The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) Trial : First Randomized Placebo-Controlled Study of Myoblast Transplantation by MENASCHE, Philippe, ALFIERI, Ottavio, LAKE, Stephen, CHATELLIER, Gilles, SOLOMON, Scott, DESNOS, Michel, HAGEGE, Albert A, JANSSENS, Stefan, MCKENNA, William, REICHENSPURNER, Hermann, TRINQUART, Ludovic, VILQUIN, Jean-Thomas, MAROLLEAU, Jean-Pierre, SEYMOUR, Barbara, LARGHERO, Jérome

“…Phase I clinical studies have demonstrated the feasibility of implanting autologous skeletal myoblasts in postinfarction scars. However, they have failed to…”
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Skeletal myoblast transplantation through a catheter-based coronary sinus approach: an effective means of improving function of infarcted myocardium by Brasselet, Camille, Morichetti, Miguel Cortes, Messas, Emmanuel, Carrion, Claire, Bissery, Alvine, Bruneval, Patrick, Vilquin, Jean-Thomas, Lafont, Antoine, Hagège, Albert A., Menasché, Philippe, Desnos, Michel

“…Aims This study was designed to assess the functional effects of a transvenous coronary sinus technique of skeletal myoblast delivery in infarcted myocardium…”
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Prevalence and clinical phenotype of hereditary transthyretin amyloid cardiomyopathy in patients with increased left ventricular wall thickness by Damy, Thibaud, Costes, Bruno, Hagège, Albert A, Donal, Erwan, Eicher, Jean-Christophe, Slama, Michel, Guellich, Aziz, Rappeneau, Stéphane, Gueffet, Jean-Pierre, Logeart, Damien, Planté-Bordeneuve, Violaine, Bouvaist, Hélène, Huttin, Olivier, Mulak, Geneviève, Dubois-Randé, Jean-Luc, Goossens, Michel, Canoui-Poitrine, Florence, Buxbaum, Joel N

“…Increased left ventricular wall thickness (LVWT) is a common finding in cardiology. It is not known how often hereditary transthyretin-related familial amyloid…”
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Temporal patterns of bone marrow cell differentiation following transplantation in doxorubicin-induced cardiomyopathy by AGBULUT, Onnik, MENOT, Marie-Laurence, ZHENLIN LI, MAROTTE, Francoise, PAULIN, Denise, HAGEGE, Albert A, CHOMIENNE, Christine, SAMUEL, Jane-Lyse, MENASCHE, Philippe

“…Recent studies have suggested benefits of bone marrow cell transplantation for the regeneration of ischemic cardiac tissue. To extend the potential of cell…”
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Mitral valve disease—morphology and mechanisms by Levine, Robert A., Hagége, Albert A., Judge, Daniel P., Padala, Muralidhar, Dal-Bianco, Jacob P., Aikawa, Elena, Beaudoin, Jonathan, Bischoff, Joyce, Bouatia-Naji, Nabila, Bruneval, Patrick, Butcher, Jonathan T., Carpentier, Alain, Chaput, Miguel, Chester, Adrian H., Clusel, Catherine, Delling, Francesca N., Dietz, Harry C., Dina, Christian, Durst, Ronen, Fernandez-Friera, Leticia, Handschumacher, Mark D., Jensen, Morten O., Jeunemaitre, Xavier P., Marec, Hervé Le, Tourneau, Thierry Le, Markwald, Roger R., Mérot, Jean, Messas, Emmanuel, Milan, David P., Neri, Tui, Norris, Russell A., Peal, David, Perrocheau, Maelle, Probst, Vincent, Pucéat, Michael, Rosenthal, Nadia, Solis, Jorge, Schott, Jean-Jacques, Schwammenthal, Ehud, Slaugenhaupt, Susan A., Song, Jae-Kwan, Yacoub, Magdi H.

“…Key Points Mitral valve disease is a major cause of heart failure and mortality Even in adult life, the mitral valve is a dynamic structure and therapeutically…”
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Effect of Losartan on Mitral Valve Changes After Myocardial Infarction by Bartko, Philipp E., Dal-Bianco, Jacob P., Guerrero, J. Luis, Beaudoin, Jonathan, Szymanski, Catherine, Kim, Dae-Hee, Seybolt, Margo M., Handschumacher, Mark D., Sullivan, Suzanne, Garcia, Michael L., Titus, James S., Wylie-Sears, Jill, Irvin, Whitney S., Messas, Emmanuel, Hagège, Albert A., Carpentier, Alain, Aikawa, Elena, Bischoff, Joyce, Levine, Robert A.

“…After myocardial infarction (MI), mitral valve (MV) tethering stimulates adaptive leaflet growth, but counterproductive leaflet thickening and fibrosis augment…”
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Skeletal myoblast transplantation in ischemic heart failure : Long-term follow-up of the first phase I cohort of patients by HAGEGE, Albert A, MAROLLEAU, Jean-Pierre, DESNOS, Michel, MENASCHE, Philippe, VILQUIN, Jean-Thomas, ALHERIBERE, Armelle, PEYRARD, Séverine, DUBOC, Denis, ABERGEL, Eric, MESSAS, Emmanuel, MOUSSEAUX, Elie, SCHWARTZ, Ketty

“…Skeletal myoblast (SM) transplantation (Tx) in a post-myocardial infarction (MI) scar experimentally improves left ventricular (LV) ejection fraction (EF)…”
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Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy by Maron, Martin S., Masri, Ahmad, Nassif, Michael E., Barriales-Villa, Roberto, Arad, Michael, Cardim, Nuno, Choudhury, Lubna, Claggett, Brian, Coats, Caroline J., Düngen, Hans-Dirk, Garcia-Pavia, Pablo, Hagège, Albert A., Januzzi, James L., Lee, Matthew M.Y., Lewis, Gregory D., Ma, Chang-Sheng, Michels, Michelle, Olivotto, Iacopo, Oreziak, Artur, Owens, Anjali T., Spertus, John A., Solomon, Scott D., Tfelt-Hansen, Jacob, van Sinttruije, Marion, Veselka, Josef, Watkins, Hugh, Jacoby, Daniel L., Heitner, Stephen B., Kupfer, Stuart, Malik, Fady I., Meng, Lisa, Wohltman, Amy, Abraham, Theodore P.

“…Among patients with symptomatic obstructive hypertrophic cardiomyopathy, treatment with aficamten led to a greater increase in peak oxygen consumption than…”
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Mapping Myocardial Fiber Orientation Using Echocardiography-Based Shear Wave Imaging by Wei-Ning Lee, Pernot, M., Couade, M., Messas, E., Bruneval, P., Bel, A., Hagege, A. A., Fink, M., Tanter, M.

“…The assessment of disrupted myocardial fiber arrangement may help to understand and diagnose hypertrophic or ischemic cardiomyopathy. We hereby proposed and…”
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Long-term (1 year) functional and histological results of autologous skeletal muscle cells transplantation in rat by NAWWAR AL ATTAR, CARRION, Claire, GHOSTINE, Said, GARCIN, Isabelle, VILQUIN, Jean-Thomas, HAGEGE, Albert A, MENASCHE, Philippe

“…Several studies have demonstrated the short-term benefits of autologous skeletal muscle cell transplantation on postinfarction left ventricular function. The…”
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Composite Cell Sheets A Further Step Toward Safe and Effective Myocardial Regeneration by Cardiac Progenitors Derived From Embryonic Stem Cells by BEL, Alain, PLANAT-BERNARD, Valérie, PEYRARD, Séverine, LARGHERO, Jérôme, POULY, Julia, BINDER, Patrice, GARCIA, Sylvie, SHIMIZU, Tatsuya, SAWA, Yoshiki, OKANO, Teruo, BRUNEVAL, Patrick, DESNOS, Michel, SAITO, Atsuhiro, HAGEGE, Albert A, CASTEILLA, Louis, PUCEAT, Michel, MENASCHE, Philippe, BONNEVIE, Lionel, BELLAMY, Valérie, SABBAH, Laurent, BELLABAS, Linda, BRINON, Benjamin, VANNEAUX, Valérie, PRADEAU, Pascal

“…The safety and efficacy of myocardial regeneration using embryonic stem cells are limited by the risk of teratoma and the high rate of cell death. To address…”
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Feasibility and Performance of Noninvasive Ultrasound Therapy in Patients With Severe Symptomatic Aortic Valve Stenosis: A First-in-Human Study by Messas, Emmanuel, IJsselmuiden, Alexander, Goudot, Guillaume, Vlieger, Selina, Zarka, Samuel, Puymirat, Etienne, Cholley, Bernard, Spaulding, Christian, Hagège, Albert A., Marijon, Eloi, Tanter, Mickael, Bertrand, Benjamin, Rémond, Mathieu C., Penot, Robin, Ren, B., den Heijer, Peter, Pernot, Mathieu, Spaargaren, René

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