Search Results - "Haft, Carol Renfrew"

Down-regulation of protease-activated receptor-1 is regulated by sorting nexin 1 by Wang, Yingjie, Zhou, Yixing, Szabo, Katalin, Haft, Carol Renfrew, Trejo, JoAnn

“…Degradation or "down-regulation" of protease-activated receptor-1 (PAR1), a G protein-coupled receptor for thrombin, is critical for termination of receptor…”
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Identification of a Family of Sorting Nexin Molecules and Characterization of Their Association with Receptors by Haft, Carol Renfrew, de la Luz Sierra, Maria, Barr, Valarie A., Haft, Daniel H., Taylor, Simeon I.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Activation of Serum- and Glucocorticoid-induced Protein Kinase (Sgk) by Cyclic AMP and Insulin by Perrotti, Nicola, He, Ruth A., Phillips, Susan A., Haft, Carol Renfrew, Taylor, Simeon I.

“…Sgk (serum- and glucocorticoid-induced protein kinase) is a serine/threonine-specific protein kinase that is transcriptionally regulated by serum,…”
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Sorting Nexin 6, a Novel SNX, Interacts with the Transforming Growth Factor-β Family of Receptor Serine-Threonine Kinases by Parks, W. Tony, Frank, David B., Huff, Carla, Renfrew Haft, Carol, Martin, Jennifer, Meng, Xianwang, de Caestecker, Mark P., McNally, James G., Reddi, Amit, Taylor, Simeon I., Roberts, Anita B., Wang, Tongwen, Lechleider, Robert J.

“…Sorting nexins (SNX) comprise a family of proteins with homology to several yeast proteins, including Vps5p and Mvp1p, that are required for the sorting of…”
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Identification and Characterization of SNX15, a Novel Sorting Nexin Involved in Protein Trafficking by Phillips, Susan A., Barr, Valarie A., Haft, Daniel H., Taylor, Simeon I., Haft, Carol Renfrew

“…Sorting nexins are a family of phox homology domain containing proteins that are homologous to yeast proteins involved in protein trafficking. We have…”
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A Di-leucine Motif and an Upstream Serine in the Interleukin-6 (IL-6) Signal Transducer gp130 Mediate Ligand-induced Endocytosis and Down-regulation of the IL-6 Receptor (∗) by Dittrich, Elke, Haft, Carol Renfrew, Muys, Leon, Heinrich, Peter C., Graeve, Lutz

“…The interleukin-6 (IL-6) receptor complex is composed of two different subunits, the IL-6 binding protein (IL-6R, gp80) and the signal transducing component…”
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β-cell biology in the 21st century by Margolis, Ronald, Laughlin, Maren, Haft, Carol Renfrew

“…The NIDDK Workshop: β-Cell Biology in the 21st Century: Engineering a Pathway to Greater Understanding was held at the National Institutes of Health, Bethesda,…”
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Dual Role of a Dileucine Motif in Insulin Receptor Endocytosis by Hamer, Isabelle, Haft, Carol Renfrew, Paccaud, Jean-Pierre, Maeder, Christine, Taylor, Simeon, Carpentier, Jean-Louis

“…Two leucines (Leu986 and Leu987) have recently been shown to take part in the control of human insulin receptor (HIR) internalization (Renfrew-Haft, C.,…”
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Characterization of Drosophila Insulin Receptor Substrate by Poltilove, Rachel M. Kulansky, Jacobs, Aviva R., Haft, Carol Renfrew, Xu, Pin, Taylor, Simeon I.

“…Insulin receptor substrate (IRS) proteins are phosphorylated by multiple tyrosine kinases, including the insulin receptor. Phosphorylated IRS proteins bind to…”
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A Library of 7TM Receptor C-terminal Tails by Heydorn, Arne, Søndergaard, Birgitte P., Ersbøll, Bjarne, Holst, Birgitte, Nielsen, Finn Cilius, Haft, Carol Renfrew, Whistler, Jennifer, Schwartz, Thue W.

“…Adaptor and scaffolding proteins determine the cellular targeting, the spatial, and thereby the functional association of G protein-coupled seven-transmembrane…”
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Analysis of the Juxtamembrane Dileucine Motif in the Insulin Receptor by Haft, Carol Renfrew, de La Luz Sierra, Maria, Hamer, Isabelle, Carpentier, Jean-Louis, Taylor, Simeon I.

“…Abstract Dileucine-containing motifs are involved in trans-Golgi sorting, lysosomal targeting, and internalization. Previously, we have shown that the…”
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A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP) by Heydorn, Arne, Søndergaard, Birgitte P, Ersbøll, Bjarne, Holst, Birgitte, Nielsen, Finn Cilius, Haft, Carol Renfrew, Whistler, Jennifer, Schwartz, Thue W

“…Adaptor and scaffolding proteins determine the cellular targeting, the spatial, and thereby the functional association of G protein-coupled seven-transmembrane…”
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Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes by Haft, C R, de la Luz Sierra, M, Bafford, R, Lesniak, M A, Barr, V A, Taylor, S I

“…Sorting nexin (SNX) 1 and SNX2 are mammalian orthologs of Vps5p, a yeast protein that is a subunit of a large multimeric complex, termed the retromer complex,…”
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Distinct in vitro interaction pattern of dopamine receptor subtypes with adaptor proteins involved in post-endocytotic receptor targeting by Heydorn, Arne, Søndergaard, Birgitte P, Hadrup, Niels, Holst, Birgitte, Haft, Carol Renfrew, Schwartz, Thue W

“…The mechanisms underlying targeted sorting of endocytosed receptors for recycling to the plasma membrane or degradation in lysosomes are poorly understood. In…”
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Overexpression of a Novel Sorting Nexin, SNX15, Affects Endosome Morphology and Protein Trafficking by Barr, Valarie A., Phillips, Susan A., Taylor, Simeon I., Haft, Carol Renfrew

“…Sorting nexin (SNX) 15 is a novel member of the SNX family of proteins. Although the functions of most SNXs have not yet been determined, several family…”
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Involvement of dileucine motifs in the internalization and degradation of the insulin receptor by Haft, C R, Klausner, R D, Taylor, S I

“…Dileucine motifs have been shown to be involved in trans Golgi sorting, lysosomal targeting, and internalization of a number of proteins. The insulin receptor…”
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Sorting Nexin 6, a Novel SNX, Interacts with the Transforming Growth Factor-β Family of Receptor Serine-Threonine Kinases by W. Tony Parks, David B. Frank, Carla Huff, Carol Renfrew Haft, Jennifer Martin, Xianwang Meng, Mark P. de Caestecker, James G. McNally, Amit Reddi, Simeon I. Taylor, Anita B. Roberts, Tongwen Wang, Robert J. Lechleider

“…Sorting nexins (SNX) comprise a family of proteins with homology to several yeast proteins, including Vps5p and Mvp1p, that are required for the sorting of…”
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Analysis of the Juxtamembrane Dileucine Motif in the Insulin Receptor1 by Haft, Carol Renfrew, de La Luz Sierra, Maria, Hamer, Isabelle, Carpentier, Jean-Louis, Taylor, Simeon I

“…Dileucine-containing motifs are involved in trans-Golgi sorting, lysosomal targeting, and internalization. Previously, we have shown that the dileucine motif…”
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Analysis of the Juxtamembrane Dileucine Motif in the Insulin Receptor 1 by Haft, Carol Renfrew, de La Luz Sierra, Maria, Hamer, Isabelle, Carpentier, Jean-Louis, Taylor, Simeon I.

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Deletion of 343 Amino Acids from the Carboxyl Terminus of the .beta.-Subunit of the Insulin Receptor Inhibits Insulin Signaling by Haft, Carol Renfrew, Taylor, Simeon I

“…Naturally occurring mutations in the insulin receptor gene that impair the receptor tyrosine kinase activity cause insulin resistance in vivo in a dominant…”
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