Search Results - "Hafren, Lena"
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Effects of social distancing on the incidence of Bell's palsy and sudden sensorineural hearing loss
Published in Acta oto-laryngologica (01-02-2022)“…The aetiology of idiopathic facial nerve palsy (Bell's palsy, BP) and sudden sensorineural hearing loss (SSNHL) are not known. It has been proposed that common…”
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Inheritance of NSAID‐Exacerbated Respiratory Disease
Published in Otolaryngology-head and neck surgery (01-03-2023)“…Nonsteroidal anti‐inflammatory drug (NSAID)–exacerbated respiratory disease (N‐ERD) has been considered an acquired condition. Positive first‐degree family…”
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Inflammatory Cytokines in Middle Ear Effusion of Patients With Asthma, Chronic Rhinosinusitis With Nasal Polyps With or Without NSAID Intolerance
Published in Otology & neurotology (01-08-2024)“…To measure the inflammatory cytokines of middle ear effusion (MEE) in otitis media (OM) associated with asthma and chronic rhinosinusitis with nasal polyps…”
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Removal of parotid sialoliths; techniques, complications, and success rate—A cohort study
Published in Clinical otolaryngology (01-05-2024)Get full text
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Malignant lymphoma presenting as bilateral sensorineural hearing loss—A case report
Published in Clinical case reports (01-12-2022)“…Bilateral Sensorineural Hearing Loss is a rare disease that is often associated with other complex medical conditions. Primary central nervous system lymphoma…”
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Asthma is Underdiagnosed and Often Uncontrolled in Preoperative Patients With Chronic Rhinosinusitis With Nasal Polyps
Published in Clinical and experimental allergy (25-07-2024)Get full text
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Aspergillus Sinusitis: Risk Factors and Phenotyping
Published in Journal of clinical medicine (27-04-2024)“…: can cause fungal rhinosinusitis (FRS). We aimed to identify risk factors for sinonasal disease. Patients with a positive sinonasal mycological culture for…”
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Digital otoscopy in remote consultations
Published in Laryngoscope investigative otolaryngology (01-08-2024)“…Introduction Otoscopes and otomicroscopes are the most commonly used instruments for visualizing the ear. Digital otoscopy (DO) could be used to improve…”
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Patient-Reported Control of Asthma, Nasal Polyposis, and Middle-Ear Symptoms in NSAID-Exacerbated Respiratory Disease
Published in Frontiers in allergy (15-07-2021)“…Non-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (NERD) is an adult-onset inflammatory condition of the upper and lower airways. It…”
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A mouse-to-man candidate gene study identifies association of chronic otitis media with the loci TGIF1 and FBXO11
Published in Scientific reports (02-10-2017)“…Chronic otitis media with effusion (COME) is the most common cause of hearing loss in children, and known to have high heritability. Mutant mouse models have…”
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Otitis media susceptibility and shifts in the head and neck microbiome due to SPINK5 variants
Published in Journal of medical genetics (01-07-2021)“…Otitis media (OM) susceptibility has significant heritability; however, the role of rare variants in OM is mostly unknown. Our goal is to identify novel rare…”
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Predisposition to Childhood Otitis Media and Genetic Polymorphisms within the Toll-Like Receptor 4 (TLR4) Locus
Published in PloS one (15-07-2015)“…Predisposition to childhood otitis media (OM) has a strong genetic component, with polymorphisms in innate immunity genes suspected to contribute to risk…”
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The role of CDHR3 in susceptibility to otitis media
Published in Journal of molecular medicine (Berlin, Germany) (01-11-2021)“…Otitis media (OM) is common in young children and can cause hearing loss and speech, language, and developmental delays. OM has high heritability; however,…”
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Panel 3: Genomics, precision medicine and targeted therapies
Published in International journal of pediatric otorhinolaryngology (01-03-2020)“…To review the most recent advances in human and bacterial genomics as applied to pathogenesis and clinical management of otitis media. PubMed articles…”
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A2ML1 and otitis media: novel variants, differential expression, and relevant pathways
Published in Human mutation (01-08-2019)“…A genetic basis for otitis media is established, however, the role of rare variants in disease etiology is largely unknown. Previously a duplication variant…”
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Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion
Published in Scientific reports (16-09-2016)“…To identify genetic risk factors of childhood otitis media (OM), a genome-wide association study was performed on Finnish subjects, 829 affected children, and…”
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Panel 3: Genetics and Precision Medicine of Otitis Media
Published in Otolaryngology-head and neck surgery (01-04-2017)“…Objective The objective is to perform a comprehensive review of the literature up to 2015 on the genetics and precision medicine relevant to otitis media. Data…”
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Multi-omic studies on missense PLG variants in families with otitis media
Published in Scientific reports (14-09-2020)“…Otitis media (OM), a very common disease in young children, can result in hearing loss. In order to potentially replicate previously reported associations…”
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ABO Genotype and Blood Type Are Associated with Otitis Media
Published in Genetic testing and molecular biomarkers (01-11-2019)“…To determine if there is an association between variants or blood types and otitis media. DNA samples from 214 probands from Finnish families with recurrent…”
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Genetic background and the risk of otitis media
Published in International journal of pediatric otorhinolaryngology (01-01-2012)“…Abstract Objective Otitis media is a multifactorial disease where genetic background may have an important role. For genome-wide association studies, it is…”
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