Search Results - "Hafner, Sophie"

Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments by Hafner, Anne-Sophie, Donlin-Asp, Paul G, Leitch, Beulah, Herzog, Etienne, Schuman, Erin M

“…There is ample evidence for localization of messenger RNAs (mRNAs) and protein synthesis in neuronal dendrites; however, demonstrations of these processes in…”
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How mRNA Localization and Protein Synthesis Sites Influence Dendritic Protein Distribution and Dynamics by Fonkeu, Yombe, Kraynyukova, Nataliya, Hafner, Anne-Sophie, Kochen, Lisa, Sartori, Fabio, Schuman, Erin M., Tchumatchenko, Tatjana

“…Proteins drive the function of neuronal synapses. The synapses are distributed throughout the dendritic arbor, often hundreds of micrometers away from the…”
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Synaptic logistics: Competing over shared resources by Hafner, Anne-Sophie, Triesch, Jochen

“…High turnover rates of synaptic proteins imply that synapses constantly need to replace their constituent building blocks. This requires sophisticated supply…”
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Competition for synaptic building blocks shapes synaptic plasticity by Triesch, Jochen, Vo, Anh Duong, Hafner, Anne-Sophie

“…Changes in the efficacies of synapses are thought to be the neurobiological basis of learning and memory. The efficacy of a synapse depends on its current…”
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Lengthening of the stargazin cytoplasmic tail increases synaptic transmission by promoting interaction to deeper domains of PSD-95 by Hafner, Anne-Sophie, Penn, Andrew C., Grillo-Bosch, Dolors, Retailleau, Natacha, Poujol, Christel, Philippat, Amandine, Coussen, Françoise, Sainlos, Matthieu, Opazo, Patricio, Choquet, Daniel

“…PSD-95 is a prominent organizer of the postsynaptic density (PSD) that can present a filamentous orientation perpendicular to the plasma membrane. Interactions…”
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Unconventional secretory processing diversifies neuronal ion channel properties by Hanus, Cyril, Geptin, Helene, Tushev, Georgi, Garg, Sakshi, Alvarez-Castelao, Beatriz, Sambandan, Sivakumar, Kochen, Lisa, Hafner, Anne-Sophie, Langer, Julian D, Schuman, Erin M

“…N-glycosylation - the sequential addition of complex sugars to adhesion proteins, neurotransmitter receptors, ion channels and secreted trophic factors as they…”
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Statistical Laws of Protein Motion in Neuronal Dendritic Trees by Sartori, Fabio, Hafner, Anne-Sophie, Karimi, Ali, Nold, Andreas, Fonkeu, Yombe, Schuman, Erin M., Tchumatchenko, Tatjana

“…Across their dendritic trees, neurons distribute thousands of protein species that are necessary for maintaining synaptic function and plasticity and that need…”
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Shisa6 traps AMPA receptors at postsynaptic sites and prevents their desensitization during synaptic activity by Klaassen, Remco V., Stroeder, Jasper, Coussen, Françoise, Hafner, Anne-Sophie, Petersen, Jennifer D., Renancio, Cedric, Schmitz, Leanne J. M., Normand, Elisabeth, Lodder, Johannes C., Rotaru, Diana C., Rao-Ruiz, Priyanka, Spijker, Sabine, Mansvelder, Huibert D., Choquet, Daniel, Smit, August B.

“…Trafficking and biophysical properties of AMPA receptors (AMPARs) in the brain depend on interactions with associated proteins. We identify Shisa6, a single…”
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Robust differentiation of human enteroendocrine cells from intestinal stem cells by Zeve, Daniel, Stas, Eric, de Sousa Casal, Joshua, Mannam, Prabhath, Qi, Wanshu, Yin, Xiaolei, Dubois, Sarah, Shah, Manasvi S., Syverson, Erin P., Hafner, Sophie, Karp, Jeffrey M., Carlone, Diana L., Ordovas-Montanes, Jose, Breault, David T.

“…Enteroendocrine (EE) cells are the most abundant hormone-producing cells in humans and are critical regulators of energy homeostasis and gastrointestinal…”
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Computational insights into mRNA and protein dynamics underlying synaptic plasticity rules by Wagle, Surbhit, Kraynyukova, Nataliya, Hafner, Anne-Sophie, Tchumatchenko, Tatjana

“…Recent advances in experimental techniques provide an unprecedented peek into the intricate molecular dynamics inside synapses and dendrites. The experimental…”
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Glutamate-Induced AMPA Receptor Desensitization Increases Their Mobility and Modulates Short-Term Plasticity through Unbinding from Stargazin by Constals, Audrey, Penn, Andrew C., Compans, Benjamin, Toulmé, Estelle, Phillipat, Amandine, Marais, Sébastien, Retailleau, Natacha, Hafner, Anne-Sophie, Coussen, Françoise, Hosy, Eric, Choquet, Daniel

“…Short-term plasticity of AMPAR currents during high-frequency stimulation depends not only on presynaptic transmitter release and postsynaptic AMPAR recovery…”
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mRNA ist der Schlüssel für die Beschreibung der Proteindynamik in Neuronen by Kraynyukova, Nataliya, Hafner, Anne-Sophie, Tchumatchenko, Tatjana

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Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition by Vogl, Annette M, Brockmann, Marisa M, Giusti, Sebastian A, Maccarrone, Giuseppina, Vercelli, Claudia A, Bauder, Corinna A, Richter, Julia S, Roselli, Francesco, Hafner, Anne-Sophie, Dedic, Nina, Wotjak, Carsten T, Vogt-Weisenhorn, Daniela M, Choquet, Daniel, Turck, Christoph W, Stein, Valentin, Deussing, Jan M, Refojo, Damian

“…The authors report that neddylation is required for dendritic spine development and stability, and loss of neddylation in excitatory forebrain neurons leads to…”
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Super-resolution imaging and estimation of protein copy numbers at single synapses with DNA-point accumulation for imaging in nanoscale topography by Böger, Carolin, Hafner, Anne-Sophie, Schlichthärle, Thomas, Strauss, Maximilian T, Malkusch, Sebastian, Endesfelder, Ulrike, Jungmann, Ralf, Schuman, Erin M, Heilemann, Mike

“…In the brain, the strength of each individual synapse is defined by the complement of proteins present or the “local proteome.” Activity-dependent changes in…”
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Förster Resonance Energy Transfer (FRET) Analysis of the C-Terminal Domain of Fp-Tagged Homomeric and Heteromeric AMPARs Upon Phosphorylation by Zachariassen, Linda G., Hafner, Anne-Sophie, Choquet, Daniel, Kristensen, Anders S.

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