Search Results - "Hafkamp, Florianne M.J."
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Dexamethasone, but Not Vitamin D or A, Dampens the Inflammatory Neutrophil Response to Protect At-risk COVID-19 Patients
Published in Immune network (01-08-2022)“…Dexamethasone (DEX) was the first drug shown to save lives of critically ill coronavirus disease 2019 (COVID-19) patients suffering from respiratory distress…”
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Efficient Neutrophil Activation Requires Two Simultaneous Activating Stimuli
Published in International journal of molecular sciences (18-09-2021)“…Neutrophils are abundantly present in the synovium and synovial fluid of patients suffering from arthritis. Neutrophils can be activated by a multitude of…”
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VSTM1-v2 does not drive human Th17 cell differentiation: A replication study
Published in PloS one (13-04-2023)“…Signal inhibitory receptor on leukocytes-1 (SIRL-1) is an immune inhibitory receptor expressed on human myeloid cells. We previously showed that dendritic cell…”
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Retinoic acid‐loaded liposomes induce human mucosal CD103+ dendritic cells that inhibit Th17 cells and drive regulatory T‐cell development in vitro
Published in European journal of immunology (01-05-2024)“…The active vitamin A metabolite, all‐trans‐retinoic acid (RA), primes precursor dendritic cells (DCs) into a mucosal phenotype with tolerogenic properties…”
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Targeting DCs for Tolerance Induction: Don't Lose Sight of the Neutrophils
Published in Frontiers in immunology (05-10-2021)“…Chronic inflammatory disorders (CID), such as autoimmune diseases, are characterized by overactivation of the immune system and loss of immune tolerance. T…”
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Aberrant neutrophil degranulation in hospitalized patients with COVID‐19 partially remains for 6 months
Published in European journal of immunology (01-01-2024)“…Neutrophils are important players in COVID‐19, contributing to tissue damage by release of inflammatory mediators, including ROS and neutrophil elastase…”
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Dexamethasone, but Not Vitamin D or A, Dampens the Inflammatory Neutrophil Response to Protect At-risk COVID-19 Patients
Published in Immune network (2022)Get full text
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Vitamin D3 Priming of Dendritic Cells Shifts Human Neutrophil-Dependent Th17 Cell Development to Regulatory T Cells
Published in Frontiers in immunology (07-07-2022)“…Vitamin D3 (VD3) is a potential adjuvant for use in tolerogenic vaccine formulations that target dendritic cells (DCs) for the treatment of chronic…”
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