Search Results - "Hafez, Alexander K."
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Sex-Dependent effects of developmental arsenic exposure on methylation capacity and methylation regulation of the glucocorticoid receptor system in the embryonic mouse brain
Published in Toxicology reports (01-01-2015)“…Previously we have shown that prenatal moderate arsenic exposure (50 ppb) disrupts glucocorticoid receptor (GR) programming and that these changes continue…”
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A psychiatric disease-related circular RNA controls synaptic gene expression and cognition
Published in Molecular psychiatry (01-11-2020)“…Although circular RNAs (circRNAs) are enriched in the mammalian brain, very little is known about their potential involvement in brain function and psychiatric…”
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Journal Article -
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Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain
Published in Toxicology and applied pharmacology (01-10-2015)“…Epidemiological studies report that arsenic exposure via drinking water adversely impacts cognitive development in children and, in adults, can lead to greater…”
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A bidirectional competitive interaction between circHomer1 and Homer1b within the orbitofrontal cortex regulates reversal learning
Published in Cell reports (Cambridge) (18-01-2022)“…Although circular RNAs (circRNAs) are enriched in the brain, their relevance for brain function and psychiatric disorders is poorly understood. Here, we show…”
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