Search Results - "Haeusler, Sebastian"
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Perinatal Gram-Positive Bacteria Exposure Elicits Distinct Cytokine Responses In Vitro
Published in International journal of molecular sciences (30-12-2020)“…During pregnancy, infections caused by the gram-positive bacteria ( ), ( ), and ( ) are major reasons for preterm labor, neonatal prematurity, meningitis, or…”
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Successful containment of Covid‐19 outbreak in a large maternity and perinatal center while continuing clinical service
Published in Pediatric allergy and immunology (01-07-2020)“…With increasing number of SARS‐CoV‐2 infections and COVID‐19 patients to be taken care of by the health system, more and more health workers become affected by…”
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Micro-ribonucleic acids and extracellular vesicles repertoire in the spent culture media is altered in women undergoing In Vitro Fertilization
Published in Scientific reports (19-10-2017)“…MicroRNAs (miRNAs) are class of small RNA molecules with major impact on gene regulation. We analyzed the potential of miRNAs secreted from pre-implantation…”
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Immune response to SARS-CoV-2 in health care workers following a COVID-19 outbreak: A prospective longitudinal study
Published in Journal of clinical virology (01-09-2020)“…Currently, little is known about the progression of an immune response against SARSCoV- 2 upon infection or sub-infection-exposure over time. We examined the…”
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Influences of adjuvant treatments in hormone receptor positive breast cancer on receptor conversion in recurrent breast cancer
Published in Archives of gynecology and obstetrics (01-02-2019)“…Background To examine influences on the receptor status of a local cohort of patients with recurrent breast cancer after primary diagnosis of hormone receptor…”
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Prolonged Exposition with Hyperthermic Intraperitoneal Chemotherapy (HIPEC) May Provide Survival Benefit after Cytoreductive Surgery (CRS) in Advanced Primary Epithelial Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
Published in Cancers (06-07-2022)“…Background: The usage of cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) for advanced gynecological cancers is…”
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Morphokinetic analysis of early human embryonic development and its relationship to endometriosis resection: a retrospective time-lapse study using the KIDScore™ D3 and D5 implantation data algorithm
Published in Archives of gynecology and obstetrics (01-08-2023)“…Research question Does complete resection of endometriosis improve embryo quality as assessed by morphokinetic parameters using time-lapse microscopy? Design…”
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SARS-CoV-2 in pregnancy and possible transfer of immunity: assessment of peripartal maternal and neonatal antibody levels and a longitudinal follow-up
Published in Journal of perinatal medicine (27-07-2021)“…In the current Severe Acute Respiratory Distress Coronavirus 2 (SARS-CoV-2) pandemic there is still great uncertainty about the effects of an infection in…”
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Evaluating the Use of Circulating MicroRNA Profiles for Lung Cancer Detection in Symptomatic Patients
Published in JAMA oncology (01-05-2020)“…The overall low survival rate of patients with lung cancer calls for improved detection tools to enable better treatment options and improved patient outcomes…”
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Evaluation of clinical parameters influencing the development of bone metastasis in breast cancer
Published in BMC cancer (12-05-2016)“…The development of metastases is a negative prognostic parameter for the clinical outcome of breast cancer. Bone constitutes the first site of distant…”
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Cognate Nonlytic Interactions between CD8 + T Cells and Breast Cancer Cells Induce Cancer Stem Cell-like Properties
Published in Cancer research (Chicago, Ill.) (01-04-2019)“…Targeting of tumor immune escape mechanisms holds enormous therapeutic potential. Still, most patients progress under immune checkpoint blockade and some even…”
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Role of HIPEC after Complete Cytoreductive Surgery (CRS) in Peritoneal Recurrence of Platinum-Sensitive Recurrent Ovarian Cancer (OC): The Aim for Standardization at Two Reference Centers for CRS
Published in Cancers (07-01-2023)“…This bicentric study evaluated cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) for platinum-sensitive recurrent…”
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Peripartal anti-SARS-CoV-2-IgA/IgG in asymptomatic pregnant women during regional SARS-CoV-2-outbreak
Published in Journal of perinatal medicine (27-07-2021)“…The Severe Acute Respiratory Distress Corona Virus 2 (SARS-CoV-2) pandemic poses special challenges for the society and especially the medical staff. Even if a…”
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The Role of Deconstructive Teaching in the Training of Laparoscopy
Published in Journal of the Society of Laparoendoscopic Surgeons (01-04-2019)“…Skills-lab training is crucial for the development of advanced laparoscopic skills. In this study, we examined whether a systematic deconstructive and…”
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Anti-CD39 and anti-CD73 antibodies A1 and 7G2 improve targeted therapy in ovarian cancer by blocking adenosine-dependent immune evasion
Published in American journal of translational research (01-01-2014)“…The ectonucleotidases CD39 and CD73 degrade ATP to adenosine which inhibits immune responses via the A2A adenosine receptor (ADORA2A) on T and NK cells. The…”
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Postnatal SARS‐CoV‐2 infection and immunological reaction: A prospective family cohort study
Published in Pediatric allergy and immunology (01-10-2020)Get full text
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CD33+/HLA-DRneg and CD33+/HLA-DR+/− Cells: Rare Populations in the Human Decidua with Characteristics of MDSC
Published in American journal of reproductive immunology (1989) (01-05-2016)“…Problem Human pregnancy needs a remarkable local immune tolerance toward the conceptus. Myeloid‐derived suppressor cells (MDSC) are important players promoting…”
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Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity
Published in Cancer Immunology, Immunotherapy (01-10-2011)“…The ectonucleotidases CD39 and CD73 degrade immune stimulatory ATP to adenosine that inhibits T and NK cell responses via the A 2A adenosine receptor…”
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Adenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages – a self-amplifying, CD39- and CD73-dependent mechanism for tumor immune escape
Published in Journal for immunotherapy of cancer (16-08-2016)“…BackgroundOvarian cancer (OvCA) tissues show abundant expression of the ectonucleotidases CD39 and CD73 which generate immunomodulatory adenosine, thereby…”
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Pattern of metastatic spread and subcategories of breast cancer
Published in Archives of gynecology and obstetrics (2017)“…Purpose The development of metastases is the most aggressive attribute of breast cancer. In this retrospective multicenter study, we evaluated if and how the…”
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