Search Results - "Haenggeli, Kai"

Endochin-like quinolones (ELQs) and bumped kinase inhibitors (BKIs): Synergistic and additive effects of combined treatments against Neospora caninum infection in vitro and in vivo by Anghel, Nicoleta, Imhof, Dennis, Winzer, Pablo, Balmer, Vreni, Ramseier, Jessica, Haenggeli, Kai, Choi, Ryan, Hulverson, Matthew A., Whitman, Grant R., Arnold, Samuel L.M., Ojo, Kayode K., Van Voorhis, Wesley C., Doggett, J. Stone, Ortega-Mora, Luis M., Hemphill, Andrew

“…The apicomplexan parasite Neospora caninum is an important causative agent of congenital neosporosis, resulting in abortion, birth of weak offspring and…”
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Single- and duplex TaqMan-quantitative PCR for determining the copy numbers of integrated selection markers during site-specific mutagenesis in Toxoplasma gondii by CRISPR-Cas9 by Hänggeli, Kai Pascal Alexander, Hemphill, Andrew, Müller, Norbert, Schimanski, Bernd, Olias, Philipp, Müller, Joachim, Boubaker, Ghalia

“…Herein, we developed a single and a duplex TaqMan quantitative PCR (qPCR) for absolute quantification of copy numbers of integrated dihydrofolate…”
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In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma gondii oocysts by Imhof, Dennis, Anghel, Nicoleta, Winzer, Pablo, Balmer, Vreni, Ramseier, Jessica, Hänggeli, Kai, Choi, Ryan, Hulverson, Matthew A., Whitman, Grant R., Arnold, Samuel L.M., Ojo, Kayode K., Van Voorhis, Wesley C., Doggett, J. Stone, Ortega-Mora, Luis M., Hemphill, Andrew

“…Bumped kinase inhibitors (BKIs) target the apicomplexan calcium-dependent protein kinase 1 (CDPK1). BKI-1748, a 5-aminopyrazole-4-carboxamide compound when…”
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Differential Affinity Chromatography Coupled to Mass Spectrometry: A Suitable Tool to Identify Common Binding Proteins of a Broad-Range Antimicrobial Peptide Derived from Leucinostatin by Müller, Joachim, Boubaker, Ghalia, Imhof, Dennis, Hänggeli, Kai, Haudenschild, Noé, Uldry, Anne-Christine, Braga-Lagache, Sophie, Heller, Manfred, Ortega-Mora, Luis-Miguel, Hemphill, Andrew

“…Leucinostatins are antimicrobial peptides with a broad range of activities against infectious agents as well as mammalian cells. The leucinostatin-derivative…”
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In Vitro versus in Mice: Efficacy and Safety of Decoquinate and Quinoline- O -Carbamate Derivatives against Experimental Infection with Neospora caninum Tachyzoites by Ramseier, Jessica, Imhof, Dennis, Hänggeli, Kai Pascal Alexander, Anghel, Nicoleta, Boubaker, Ghalia, Beteck, Richard M, Ortega-Mora, Luis-Miguel, Haynes, Richard K, Hemphill, Andrew

“…The effects of decoquinate (DCQ) and three -quinoline-carbamate-derivatives were investigated using human foreskin fibroblasts (HFF) infected with tachyzoites…”
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