Search Results - "Haemers, A"

Inhibitors of the Purine Salvage Pathway: A Valuable Approach for Antiprotozoal Chemotherapy? by Berg, M, Van der Veken, P, Goeminne, A, Haemers, A, Augustyns, K

“…For many years, the purine salvage pathway of parasitic protozoa has been regarded as an attractive chemotherapeutic target. Parasitic protozoa lack de novo…”
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The therapeutic potential of inhibitors of dipeptidyl peptidase IV (DPP IV) and related proline-specific dipeptidyl aminopeptidases by Augustyns, K, Van der Veken, P, Senten, K, Haemers, A

“…In this review the structural and functional aspects of dipeptidyl peptidase IV (DPP IV) will be described, and the therapeutic potential of DPP IV inhibitors…”
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Development of Irreversible Diphenyl Phosphonate Inhibitors for Urokinase Plasminogen Activator by Joossens, J, Van der Veken, P, Lambeir, A.-M, Augustyns, K, Haemers, A

“…In this letter we report the synthesis and biochemical evaluation of selective, irreversible diphenyl phosphonate inhibitors for urokinase plasminogen…”
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Trypanothione as a target in the design of antitrypanosomal and antileishmanial agents by Augustyns, K, Amssoms, K, Yamani, A, Rajan, P K, Haemers, A

“…Trypanothione is the key molecule in the defence mechanism of Trypanosoma and Leishmania against oxidative stress. The uniqueness of trypanothione makes the…”
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Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors by Goeminne, A., McNaughton, M., Bal, G., Surpateanu, G., Van Der Veken, P., De Prol, S., Versées, W., Steyaert, J., Haemers, A., Augustyns, K.

“…Nucleoside hydrolase (NH) is a key enzyme in the purine salvage pathway. The purine specificity of the IAG-NH from Trypanosoma vivax is at least in part due to…”
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The unique properties of dipeptidyl-peptidase IV (DPP IV / CD26) and the therapeutic potential of DPP IV inhibitors by Augustyns, K, Bal, G, Thonus, G, Belyaev, A, Zhang, X M, Bollaert, W, Lambeir, A M, Durinx, C, Goossens, F, Haemers, A

“…This review deals with the properties and functions of dipeptidyl peptidase IV (DPP IV, EC 3.4.14.5). This membrane anchored ecto-protease has been identified…”
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1,2,3-Triazolylalkylribitol derivatives as nucleoside hydrolase inhibitors by Goeminne, A., McNaughton, M., Bal, G., Surpateanu, G., Van der Veken, P., De Prol, S., Versées, W., Steyaert, J., Apers, S., Haemers, A., Augustyns, K.

“…A range of novel 1,2,3-triazolylalkylribitol derivatives were synthesized and evaluated as nucleoside hydrolase inhibitors. The most active compound ( 11a) has…”
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Pyrrolidides: synthesis and structure-activity relationship as inhibitors of dipeptidyl peptidase IV by Augustyns, K.J.L., Lambeir, A.M., Borloo, M, De Meester, I, Vedernikova, I, Vanhoof, G, Hendriks, D, Scharpé, S, Haemers, A

“…Dipeptidyl peptidase IV cleaves specifically the peptide bond at the carboxyl side of a proline at the penultimate N-terminal position of a peptide. It is…”
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Quantum mechanical evaluation of the anodic oxidation of phenolic compounds by Vedernikova, I., Tollenaere, J. P., Haemers, A.

“…The electronic structures of a series of phenols, phenoxyl cation radicals and phenoxyl radicals were calculated by the AM1 method. On the basis of the…”
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Mycobacteria and the new quinolones by LEYSEN, D. C, HAEMERS, A, PATTYN, S. R

“…The discovery of the new quinolones has broadened rather unexpectedly the therapeutic armamentarium against infections with mycobacteria. It has indeed been…”
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Laser Cladding of Stainless Steel with Hastelloy by Haemers, T. A. M., Rickerby, D. G., Lanza, F., Geiger, F., Mittemeijer, E. J.

“…No s…”
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Submicron oil-in-water emulsion formulations for mefloquine and halofantrine : Effect of electric-charge inducers on antimalarial activity in mice by MBELA, T. K. M, DEHARO, E, HAEMERS, A, LUDWIG, A

“…Stearylamine, oleic acid, phosphatidylserine and dicetylphosphate have been studied to determine their capacity to induce electric charge on non-ionic…”
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Study of the enzymatic degradation of vasostatin I and II and their precursor chromogranin A by dipeptidyl peptidase IV using high-performance liquid chromatography/electrospray mass spectrometry by Zhang, X. Y., De Meester, I., Lambeir, A.-M., Dillen, L., Van Dongen, W., Esmans, E. L., Haemers, A., Scharpé, S., Claeys, M.

“…The interaction of dipeptidyl peptidase IV with structurally related proteins differing in chain length, namely vasostatin I and II and their precursor protein…”
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Influence of N substitution on antimycobacterial activity of ciprofloxacin by HAEMERS, A, LEYSEN, D. C, BOLLAERT, W, ZHANG, M, PATTYN, S. R

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Effect of l-tryptophan, l-5-hydroxytryptophan and l-tryptophan prodrugs on the extracellular levels of 5-HT and 5-HIAA in the hippocampus of the rat using microdialysis by Thorré, Katrien, Sarre, S., Twahirwa, E., Meeusen, R., Ebinger, G., Haemers, A., Michotte, Y.

“…The effect of the natural precursors and synthetic prodrugs of serotonin (5-HT) on the extracellular levels of 5-HT and its metabolite 5-hydroxyindoleacetic…”
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AN EFFICIENT SYNTHESIS OF ORTHOGONALLY PROTECTED SPERMIDINE by Amssoms, K., Augustyns, K., Yamani, A., Zhang, M., Haemers, A.

“…A major problem in the use of spermidine for the synthesis of biologically interesting compounds is the selective orthogonal protection of the three different…”
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Fluoro-Olefins as Peptidomimetic Inhibitors of Dipeptidyl Peptidases by Van der Veken, Pieter, Senten, Kristel, Kertèsz, István, De Meester, Ingrid, Lambeir, Anne-Marie, Maes, Marie-Berthe, Scharpé, Simon, Haemers, Achiel, Augustyns, Koen

“…The feasibility of the fluoro-olefin function as a peptidomimetic group in inhibitors for dipeptidyl peptidase IV and II (DPP IV and DPP II) is investigated by…”
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Specific inhibition of CD26/DPP IV enzymatic activity in allograft recipients: effects on humoral immunity by Korom, S, De Meester, I, Schmidbauer, G, Pratschke, J, Brendel, M.D, Durinx, C, Schwemmle, K, Haemers, A, Scharpé, S, Kupiec-Weglinski, J.W

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Quinolone antimicrobial agents: structure-activity relationships by Zhang, M Q, Haemers, A

“…The rapid growth in the quinolone research changed the whole face of the previous SAR concepts. So far structural modifications at all positions of the…”
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Simulation of cellular-dendritic solidification structures of binary alloys in three-dimensional growth using a multiparticle diffusion-limited aggregation model by Haemers, T. A. M., Rickerby, D. G., Mittemeijer, E. J.

“…Solidification in binary alloy melts was simulated with two different three-dimensional models, that differ in the way the role of the solid/liquid interface…”
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