Search Results - "Haeberle, R."

Calponin decreases the rate of cross-bridge cycling and increases maximum force production by smooth muscle myosin in an in vitro motility assay by HAEBERLE, J. R

“…Mammalian smooth muscles, like invertebrate "catch" muscles, dynamically regulate the rate of cross-bridge cycling. During sustained contractions, cross-bridge…”
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Alteration of Contractile Function and Excitation-Contraction Coupling in Dilated Cardiomyopathy by Hasenfuss, Gerd, Mulieri, Louis A, Leavitt, Bruce J, Allen, Paul D, Haeberle, Joe R, Alpert, Norman R

“…Myocardial failure in dilated cardiomyopathy may result from subcellular alterations in contractile protein function, excitation-contraction coupling…”
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High-temperature sodium dodecyl sulfate polyacrylamide gel electrophoresis by Haeberle, J R

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Myocardial force-frequency defect in mitral regurgitation heart failure is reversed by forskolin by MULIERI, L. A, LEAVITT, B. J, MARTIN, B. J, HAEBERLE, J. R, ALPERT, N. R

“…Postoperative ejection phase parameters and patient survival rates for mitral valve replacement surgery are considerably lower than for similar aortic valve…”
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Phosphorylation of caldesmon in arterial smooth muscle by Adam, L P, Haeberle, J R, Hathaway, D R

“…We have isolated caldesmon (Mr = 145,000), by immunoprecipitation, from [32P]orthophosphate-loaded porcine carotid arteries. In resting muscles, caldesmon was…”
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The effects of smooth muscle caldesmon on actin filament motility by HAEBERLE, J. R, TRYBUS, K. M, HEMRIC, M. E, WARSHAW, D. M

“…The movement of reconstituted thin filaments over an immobilized surface of thiophosphorylated smooth muscle myosin was examined using an in vitro motility…”
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Phosphorylation by protein kinase C of the 20,000-dalton light chain of myosin in intact and chemically skinned vascular smooth muscle by SUTTON, T. A, HAEBERLE, J. R

“…In the present study we tested the hypothesis that phosphorylation of the 20,000-dalton light chain subunit of smooth muscle myosin (LC20) by the…”
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Caldesmon enhances the binding of myosin to the cytoskeleton during platelet activation by HEMRIC, M. E, TRACY, P. B, HAEBERLE, J. R

“…Activation of platelets with physiological agents results in distinct cellular events such as shape change, cell aggregation, granule secretion, and clot…”
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Calponin is not phosphorylated during contractions of porcine carotid arteries by Adam, L P, Haeberle, J R, Hathaway, D R

“…Calponin and caldesmon were purified from porcine carotid arteries that were preincubated with [32P]orthophosphate, and the stoichiometry of phosphorylation…”
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Selective purification of the 20,000-Da light chains of smooth muscle myosin by Hathaway, D R, Haeberle, J R

“…The 20,000-Da light chains of gizzard smooth muscle myosin have been purified to homogeneity. Actomyosin, prepared by MgATP extraction of myofibrils, was…”
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A model for the coregulation of smooth muscle actomyosin by caldesmon, calponin, tropomyosin, and the myosin regulatory light chain by Haeberle, J R, Hemric, M E

“…The purpose of these studies was to evaluate the effects of the actin-binding proteins tropomyosin, caldesmon, and calponin on the activation of smooth muscle…”
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A radioimmunoblotting method for measuring myosin light chain phosphorylation levels in smooth muscle by Hathaway, D R, Haeberle, J R

“…A method for measuring the molar stoichiometry of myosin light chain phosphorylation in intact smooth muscle has been developed. Antiserum to the 20,000-Da…”
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Limited autolysis reduces the Ca2+ requirement of a smooth muscle Ca2+-activated protease by Hathaway, D R, Werth, D K, Haeberle, J R

“…Chicken gizzard smooth muscle contains large amounts of Ca2+-activated protease activity. Approximately 15 mg of purified enzyme can be obtained from 1 kg of…”
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Thin-filament linked regulation of smooth muscle myosin by Haeberle, J R

“…Phosphorylation of the regulatory light chain subunit of smooth muscle myosin is sufficient, but not necessary for muscle contraction. It has been suggested…”
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R403Q and L908V mutant beta-cardiac myosin from patients with familial hypertrophic cardiomyopathy exhibit enhanced mechanical performance at the single molecule level by Palmiter, K A, Tyska, M J, Haeberle, J R, Alpert, N R, Fananapazir, L, Warshaw, D M

“…Familial hypertrophic cardiomyopathy (FHC) is a disease of the sarcomere. In the beta-myosin heavy chain gene, which codes for the mechanical enzyme myosin,…”
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Effect of primary grain size on the secondary recrystallization of mechanically alloyed oxide dispersion strengthened Ni-base superalloy by PARK, L. J, KIM, S. B, KIM, Y. G, HONG, S. H, HAEBERLE, R. M, WATWE, A. S

“…The influence of the initial microstructure of an as-extruded oxide dispersion strengthen nickel-based superalloy on the secondary recrystallization behavior…”
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Dephosphorylation of myosin by the catalytic subunit of a type-2 phosphatase produces relaxation of chemically skinned uterine smooth muscle by Haeberle, J R, Hathaway, D R, DePaoli-Roach, A A

“…It is now well-established that phosphorylation of the 20,000-dalton light chain of smooth muscle myosin (LC20) is a prerequisite for muscle contraction…”
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Phosphorylation of two sites on smooth muscle myosin. Effects on contraction of glycerinated vascular smooth muscle by Haeberle, J R, Sutton, T A, Trockman, B A

“…Contraction of glycerinated porcine carotid artery smooth muscle in response to calcium (20 microM), calmodulin (10 microM), and MgATP was associated with…”
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Caldesmon content of mammalian smooth muscles by HAEBERLE, J. R, HATHAWAY, D. R, SMITH, C. L

“…In the present study we have used a quantitative immunoblotting method to measure the caldesmon content of a variety of smooth muscles with distinctly…”
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Direct post and core pattern made with light-curing composite resin by Cohen, S M, Vaidyanathan, J, Haeberle, R C

“…An unfilled Bis-GMA composite resin can be used advantageously for making an accurate cast post and core pattern. The technique is faster and easier than…”
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