Search Results - "Hadrian, Karina"
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The role of lymphatic vessels in corneal fluid homeostasis and wound healing
Published in Journal of ophthalmic inflammation and infection (22-01-2024)“…The cornea, essential for vision, is normally avascular, transparent, and immune-privileged. However, injuries or infections can break this privilege, allowing…”
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Macrophage-Mediated Tissue Vascularization: Similarities and Differences Between Cornea and Skin
Published in Frontiers in immunology (07-04-2021)“…Macrophages are critical mediators of tissue vascularization both in health and disease. In multiple tissues, macrophages have been identified as important…”
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Macrophage variants in laboratory research: most are well done, but some are RAW
Published in Frontiers in cellular and infection microbiology (09-10-2024)“…Macrophages play a pivotal role in the innate immune response. While their most characteristic function is phagocytosis, it is important not to solely…”
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The role of the osmosensitive transcription factor NFAT5 in corneal edema resorption after injury
Published in Experimental & molecular medicine (01-03-2023)“…The osmosensitive transcription factor nuclear factor of activated T cells 5 (NFAT5; or tonicity-responsive enhancer binding protein; TonEBP) plays a key role…”
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Short-Term UVB Irradiation Leads to Persistent DNA Damage in Limbal Epithelial Stem Cells, Partially Reversed by DNA Repairing Enzymes
Published in Biology (Basel, Switzerland) (01-02-2023)“…The cornea is frequently exposed to ultraviolet (UV) radiation and absorbs a portion of this radiation. UVB in particular is absorbed by the cornea and will…”
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ABCB5+ Limbal Epithelial Stem Cells Inhibit Developmental but Promote Inflammatory (Lymph) Angiogenesis While Preventing Corneal Inflammation
Published in Cells (Basel, Switzerland) (27-06-2023)“…The limbus, the vascularized junction between the cornea and conjunctiva, is thought to function as a barrier against corneal neovascularization. However, the…”
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Different Murine High-Risk Corneal Transplant Settings Vary Significantly in Their (Lymph)angiogenic and Inflammatory Cell Signatures
Published in Investigative ophthalmology & visual science (01-12-2022)“…Pathologic conditions in the cornea, such as transplant rejection or trauma, can lead to corneal neovascularization, creating a high-risk environment that may…”
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Efficacy and safety of combined UV‐light corneal crosslinking and fine‐needle diathermy to regress pathological murine corneal (lymph)angiogenesis in vivo
Published in Acta ophthalmologica (Oxford, England) (01-11-2024)“…Purpose To compare safety and efficacy of isolated and combined UV‐light corneal crosslinking (CXL) and fine‐needle diathermy (FND) to regress pathological…”
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Pre‐incubation of corneal donor tissue with sCD83 improves graft survival via the induction of alternatively activated macrophages and tolerogenic dendritic cells
Published in American journal of transplantation (01-02-2022)“…Immune responses reflect a complex interplay of cellular and extracellular components which define the microenvironment of a tissue. Therefore, factors that…”
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The novel role of lymphatic vessels in the pathogenesis of ocular diseases
Published in Progress in retinal and eye research (01-09-2023)“…Historically, the eye has been considered as an organ free of lymphatic vessels. In recent years, however, it became evident, that lymphatic vessels or…”
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Corneal edema resorption after injury is regulated by the transcription factor NFAT5
Published in Acta ophthalmologica (Oxford, England) (01-12-2022)“…In cornea, injury or inflammation leads to an ingrowth of blood‐ and lymphatic vessels associated with corneal edema. That can lead to a loss of transparency…”
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Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula
Published in Experimental eye research (01-08-2019)“…Evidence of an age-related increase of β-synuclein (SNCB) in several parts of the visual system including the retina has been reported. SNCB is thought to…”
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