Search Results - "Hadpech, Sudarat"
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The modulatory effects of large and small extracellular vesicles from normal human urine on calcium oxalate crystallization, growth, aggregation, adhesion on renal cells, and invasion through extracellular matrix: An in vitro study
Published in Biomedicine & pharmacotherapy (01-04-2024)“…Urinary extracellular vesicles (uEVs) play important roles in physiologic condition and various renal/urological disorders. However, their roles in kidney…”
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Theranostic roles of machine learning in clinical management of kidney stone disease
Published in Computational and structural biotechnology journal (01-01-2023)“…[Display omitted] Kidney stone disease (KSD) is a common illness caused by deposition of solid minerals formed inside the kidney. The disease prevalence…”
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Calcineurin B inhibits calcium oxalate crystallization, growth and aggregation via its high calcium-affinity property
Published in Computational and structural biotechnology journal (01-01-2023)“…Calcineurin inhibitors (CNIs) are widely used in organ transplantation to suppress immunity and prevent allograft rejection. However, some transplant patients…”
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Updating on Roles of HIV Intrinsic Factors: A Review of Their Antiviral Mechanisms and Emerging Functions
Published in Intervirology (2022)“…Background: Host restriction factors are cellular proteins that inhibit specific steps of the viral life cycle. Since the 1970s, several new factors have been…”
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The upregulation of lamin A/C as a compensatory mechanism during tight junction disruption in renal tubular cells mediated by calcium oxalate crystals
Published in Current research in toxicology (01-01-2024)“…[Display omitted] •Calcium oxalate monohydrate (COM) upregulates lamin A/C.•COM reduces zonula occludens-1 (ZO-1) level and transepithelial resistance…”
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Broad-Spectrum Antiviral Activity of an Ankyrin Repeat Protein on Viral Assembly against Chimeric NL4-3 Viruses Carrying Gag/PR Derived from Circulating Strains among Northern Thai Patients
Published in Viruses (13-11-2018)“…Certain proteins have demonstrated proficient human immunodeficiency virus (HIV-1) life cycle disturbance. Recently, the ankyrin repeat protein targeting the…”
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Epithelial–mesenchymal plasticity in kidney fibrosis
Published in Genesis (New York, N.Y. : 2000) (01-02-2024)“…Summary Epithelial–mesenchymal transition (EMT) is an important biological process contributing to kidney fibrosis and chronic kidney disease. This process is…”
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Combined Antiviral Therapy Using Designed Molecular Scaffolds Targeting Two Distinct Viral Functions, HIV-1 Genome Integration and Capsid Assembly
Published in Molecular therapy. Nucleic acids (01-08-2015)“…Designed molecular scaffolds have been proposed as alternative therapeutic agents against HIV-1. The ankyrin repeat protein (AnkGAG1D4) and the zinc finger…”
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Current update on theranostic roles of cyclophilin A in kidney diseases
Published in Theranostics (01-01-2022)“…Cyclophilin A (CyPA) or peptidylprolyl isomerase A (PPIA), an immunophilin with peptidyl-prolyl isomerase (PPIase) activity, is an abundant cellular protein…”
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Alpha-tubulin relocalization is involved in calcium oxalate-induced tight junction disruption in renal epithelial cells
Published in Chemico-biological interactions (01-12-2022)“…Microtubule (MT) is associated with tight junction (TJ) structure and function. While calcium oxalate monohydrate (COM) commonly causes TJ disruption, its…”
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Tight junction and kidney stone disease
Published in Tissue barriers (02-01-2024)“…Defects of tight junction (TJ) are involved in many diseases related to epithelial cell functions, including kidney stone disease (KSD), which is a common…”
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Semi-quantification of HIV-1 protease inhibitor concentrations in clinical samples of HIV-infected patients using a gold nanoparticle-based immunochromatographic assay
Published in Analytica chimica acta (13-09-2019)“…Individual drug concentration data can be a valuable tool for the clinical management of antiretroviral therapy (ART) for the treatment of HIV infection. High…”
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Occupation of a thermoresistant-scaffold (αRep) at SP1-NC cleavage site disturbs the function of HIV-1 protease
Published in Bioscience reports (26-06-2020)“…HIV-1 nucleocapsid (NC) becomes an attractive target for the development of novel anti-HIV-1 agents. Discovering of non-antibody scaffolds that disrupt the…”
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Impairment of a membrane-targeting protein translated from a downstream gene of a “self-cleaving” T2A peptide conjunction
Published in Protein expression and purification (01-10-2018)“…The requirement for reliable bicistronic or multicistronic vectors in gene delivery systems is at the forefront of bio/biomedical technology. A method that…”
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Alpha-helicoidal HEAT-like Repeat Proteins (αRep) Selected as Interactors of HIV-1 Nucleocapsid Negatively Interfere with Viral Genome Packaging and Virus Maturation
Published in Scientific reports (27-11-2017)“…A new generation of artificial proteins, derived from alpha-helicoidal HEAT-like repeat protein scaffolds (αRep), was previously characterized as an effective…”
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A drug discovery platform: A simplified immunoassay for analyzing HIV protease activity
Published in Journal of virological methods (01-12-2012)“…► A convenient proteolytic analysis of HIV protease was created based on a standard ELISA-based system. ► Two specific monoclonal antibodies were used for…”
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