Search Results - "Hadler, Michael J."

Functional Separation of the Requirements for Establishment and Maintenance of Centromeric Heterochromatin by Partridge, Janet F., DeBeauchamp, Jennifer L., Kosinski, Aaron M., Ulrich, Dagny L., Hadler, Michael J., Noffsinger, Victoria J.P.

“…The establishment and maintenance of centromeric heterochromatin in fission yeast require the RITS complex. Comprised of centromeric siRNAs, the chromodomain…”
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MLL partial tandem duplication leukemia cells are sensitive to small molecule DOT1L inhibition by Kühn, Michael W M, Hadler, Michael J, Daigle, Scott R, Koche, Richard P, Krivtsov, Andrei V, Olhava, Edward J, Caligiuri, Michael A, Huang, Gang, Bradner, James E, Pollock, Roy M, Armstrong, Scott A

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Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma by McNeill, Robert S, Canoutas, Demitra A, Stuhlmiller, Timothy J, Dhruv, Harshil D, Irvin, David M, Bash, Ryan E, Angus, Steven P, Herring, Laura E, Simon, Jeremy M, Skinner, Kasey R, Limas, Juanita C, Chen, Xin, Schmid, Ralf S, Siegel, Marni B, Van Swearingen, Amanda E D, Hadler, Michael J, Sulman, Erik P, Sarkaria, Jann N, Anders, Carey K, Graves, Lee M, Berens, Michael E, Johnson, Gary L, Miller, C Ryan

“…Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Prognosis remains poor despite multimodal therapy. Developing alternative treatments…”
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