Primary histiocytic sarcoma of the uterine cervix: an extremely rare entity

Primary histiocytic sarcoma of the uterine cervix: an extremely rare entity

Histiocytic sarcoma (HS) is an extraordinary rare tumor and it has an offensive clinical course. HS of the uterine cervix is a far uncommon tumor with just a few cases described so far. Here we presented a case of primary HS of the uterine cervix in a 62-year-old female initially misdiagnosed as lar...

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Bibliographic Details
Published in:Revue roumaine de médecine interne (1990) Vol. 55; no. 1; pp. 53 - 56
Main Authors: Binesh, Fariba, Karimi-Zarchi, Mojgan, Vahidfar, Mohammad Reza, Hadgiabadi, Zahra Kargar
Format: Journal Article
Language:English
Published: Germany Sciendo 01-03-2017
Subjects:
Antineoplastic Agents - therapeutic use
Diagnosis, Differential
Female
histiocytic sarcoma
Histiocytic Sarcoma - complications
Histiocytic Sarcoma - diagnosis
Histiocytic Sarcoma - therapy
Humans
Hysterectomy
Metrorrhagia - etiology
Middle Aged
Treatment Outcome
Uterine Cervical Neoplasms - complications
Uterine Cervical Neoplasms - diagnosis
Uterine Cervical Neoplasms - therapy
uterine cervix
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Summary:Histiocytic sarcoma (HS) is an extraordinary rare tumor and it has an offensive clinical course. HS of the uterine cervix is a far uncommon tumor with just a few cases described so far. Here we presented a case of primary HS of the uterine cervix in a 62-year-old female initially misdiagnosed as large cell non-keratinizing squamous cell carcinoma. To the best of our knowledge, this is the first reported case of HS of the uterine cervix from Iran. The patient presented with post-menopausal vaginal bleeding. Further evaluations revealed the presence of a relatively large cervical mass that was sampled. Under the preliminary diagnosis of large cell non-keratinizing squamous cell carcinoma, the patient underwent radical surgery. Postoperative pathological examination confirmed the diagnosis of HS of the uterine cervix. The patient received chemotherapy. Clinical presentations of HS of the uterine cervix are very similar to more common cervical tumors; as a result its diagnosis relies on immunohistochemical methods. A correct diagnose could lead to the proper and timely treatment.
Bibliography:ObjectType-Case Study-2
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ISSN:1220-4749
2501-062X
DOI:10.1515/rjim-2016-0051