Search Results - "Haddox, Candace L."

Parasympathetic Innervation Regulates Tubulogenesis in the Developing Salivary Gland by Nedvetsky, Pavel I., Emmerson, Elaine, Finley, Jennifer K., Ettinger, Andreas, Cruz-Pacheco, Noel, Prochazka, Jan, Haddox, Candace L., Northrup, Emily, Hodges, Craig, Mostov, Keith E., Hoffman, Matthew P., Knox, Sarah M.

“…A fundamental question in development is how cells assemble to form a tubular network during organ formation. In glandular organs, tubulogenesis is a multistep…”
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Parasympathetic stimulation improves epithelial organ regeneration by Knox, Sarah M., Lombaert, Isabelle M. A., Haddox, Candace L., Abrams, Shaun R., Cotrim, Ana, Wilson, Adrian J., Hoffman, Matthew P.

“…Parasympathetic nerves are a vital component of the progenitor cell niche during development, maintaining a pool of progenitors for organogenesis. Injured…”
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Submandibular Parasympathetic Gangliogenesis Requires Sprouty-Dependent Wnt Signals from Epithelial Progenitors by Knosp, Wendy M., Knox, Sarah M., Lombaert, Isabelle M.A., Haddox, Candace L., Patel, Vaishali N., Hoffman, Matthew P.

“…Parasympathetic innervation is critical for submandibular gland (SMG) development and regeneration. Parasympathetic ganglia (PSG) are derived from Schwann cell…”
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Osteosarcoma in Pediatric Patients and Young Adults: A Single Institution Retrospective Review of Presentation, Therapy, and Outcome by Haddox, Candace L., Han, Gang, Anijar, Leon, Binitie, Odion, Letson, G. Douglas, Bui, Marilyn M., Reed, Damon R.

“…Background. Little is known about how cumulative chemotherapy delivery influences the poorer outcome observed in young adult (YA, 18–40 years) versus pediatric…”
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Radiation Followed by IO Is the Way to Go by Haddox, Candace L., Baldini, Elizabeth H.

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Peripheral nervous system genes expressed in central neurons induce growth on inhibitory substrates by Buchser, William J, Smith, Robin P, Pardinas, Jose R, Haddox, Candace L, Hutson, Thomas, Moon, Lawrence, Hoffman, Stanley R, Bixby, John L, Lemmon, Vance P

“…Trauma to the spinal cord and brain can result in irreparable loss of function. This failure of recovery is in part due to inhibition of axon regeneration by…”
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Role of the cytoplasmic domain of the L1 cell adhesion molecule in brain development by Nakamura, Yukiko, Lee, Suni, Haddox, Candace L., Weaver, Eli J., Lemmon, Vance P.

“…Mutations in the human L1CAM gene cause X‐linked hydrocephalus and MASA (Mental retardation, Aphasia, Shuffling gait, Adducted thumbs) syndrome. In vitro…”
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Ruxolitinib as first‐line treatment in secondary hemophagocytic lymphohistiocytosis: A single patient experience by Slostad, Jessica, Hoversten, Patrick, Haddox, Candace L., Cisak, Kamila, Paludo, Jonas, Tefferi, Ayalew

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Emerging predictive biomarkers in the management of bone and soft tissue sarcomas by Haddox, Candace L., Riedel, Richard F.

“…Soft tissue and bone sarcomas are a heterogeneous group of malignancies, each with a unique biology and clinical course. As our understanding of individual…”
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Safety and Efficacy of the Combination Lurbinectedin plus Doxorubicin from a Phase 1b Trial in Patients with Advanced/Metastatic Soft-Tissue Sarcoma by Cote, Gregory M, Haddox, Candace L, Choy, Edwin, Merriam, Priscilla A, Mazzola, Emanuele, Venkataraman, Vinayak, Alcindor, Thierry, Wagner, Andrew J, Demetri, George D, George, Suzanne

“…While cytotoxic chemotherapy is the standard first-line treatment for patients with metastatic soft-tissue sarcoma (STS), clinical outcomes remain suboptimal…”
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Diagnosis and management of dedifferentiated liposarcoma: A multidisciplinary position statement by Haddox, Candace L., Hornick, Jason L., Roland, Christina L., Baldini, Elizabeth H., Keedy, Vicki L., Riedel, Richard F.

“…•Molecular diagnostics, including MDM2 amplification by FISH, or overexpression by IHC, can help confirm a diagnosis of DDLPS.•Surgical resection should be…”
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Phase II Study of Eribulin plus Pembrolizumab in Metastatic Soft-tissue Sarcomas: Clinical Outcomes and Biological Correlates by Haddox, Candace L, Nathenson, Michael J, Mazzola, Emanuele, Lin, Jia-Ren, Baginska, Joanna, Nau, Allison, Weirather, Jason L, Choy, Edwin, Marino-Enriquez, Adrian, Morgan, Jeffrey A, Cote, Gregory M, Merriam, Priscilla, Wagner, Andrew J, Sorger, Peter K, Santagata, Sandro, George, Suzanne

“…Eribulin modulates the tumor-immune microenvironment via cGAS-STING signaling in preclinical models. This non-randomized phase II trial evaluated the…”
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Multidisciplinary approach for a high‐risk, localized soft tissue sarcoma of the trunk after unplanned nononcological resection by Haddox, Candace L., Baldini, Elizabeth H., Jagannathan, Jyothi P., Hornick, Jason L., Raut, Chandrajit P.

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Individualizing systemic therapy for advanced soft tissue sarcomas based on tumor histology and biology by Haddox, Candace L, Riedel, Richard F

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MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer by Engstrom, Lars D, Aranda, Ruth, Waters, Laura, Moya, Krystal, Bowcut, Vickie, Vegar, Laura, Trinh, David, Hebbert, Allan, Smith, Christopher R, Kulyk, Svitlana, Lawson, J David, He, Leo, Hover, Laura D, Fernandez-Banet, Julio, Hallin, Jill, Vanderpool, Darin, Briere, David M, Blaj, Alice, Marx, Matthew A, Rodon, Jordi, Offin, Michael, Arbour, Kathryn C, Johnson, Melissa L, Kwiatkowski, David J, Jänne, Pasi A, Haddox, Candace L, Papadopoulos, Kyriakos P, Henry, Jason T, Leventakos, Konstantinos, Christensen, James G, Shazer, Ronald, Olson, Peter

“…Previous studies implicated protein arginine methyltransferase 5 (PRMT5) as a synthetic lethal target for MTAP-deleted (MTAP del) cancers; however, the…”
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Phenotypic heterogeneity associated with germline GATA2 haploinsufficiency: a comprehensive kindred study by Haddox, Candace L., Carr, Ryan M., Abraham, Roshini S., Perez Botero, Juliana, Rodriguez, Vilmarie, Pardanani, Animesh, Patnaik, Mrinal M.

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Extraskeletal Osteosarcoma: Outcomes and the Role of Chemotherapy by Paludo, Jonas, Fritchie, Karen, Haddox, Candace L, Rose, Peter S, Arndt, Carola A S, Marks, Randolph S, Galanis, Evanthia, Okuno, Scott H, Robinson, Steven I

“…Extraskeletal osteosarcoma (EO) is a malignant neoplasm that produces osteoid, bone, and chondroid material without direct attachment to bone or periosteum…”
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Representation of Minorities and Women in Oncology Clinical Trials: Review of the Past 14 Years by Duma, Narjust, Vera Aguilera, Jesus, Paludo, Jonas, Haddox, Candace L, Gonzalez Velez, Miguel, Wang, Yucai, Leventakos, Konstantinos, Hubbard, Joleen M, Mansfield, Aaron S, Go, Ronald S, Adjei, Alex A

“…Many cancer clinical trials lack appropriate representation of specific patient populations, limiting their generalizability. Therefore, we determined the…”
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Aurora-A overexpression is linked to development of aggressive teratomas derived from human iPS cells by Ohmine, Seiga, Salisbury, Jeffrey L, Ingle, James, Pettinato, Giuseppe, Haddox, Candace L, Haddad, Tufia, Galanis, Evanthia, Ikeda, Yasuhiro, D'assoro, Antonino B

“…The discovery of human induced pluripotent stem cells (hiPSCs) is a promising advancement in the field of regenerative and personalized medicine. Expression of…”
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‘RED’ groups: a bottom‐up approach to wellness by Nordhues, Hannah C, Haddox, Candace L, Kashiwagi, Deanne T, Kubey, Alan A

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