Search Results - "Hadden, Elba M."

Zinc induces thymulin secretion from human thymic epithelial cells In vitro and augments splenocyte and thymocyte responses In vivo by Saha, Anutosh R., Hadden, Elba M., Hadden, John W.

“…Zinc is incorporated into zinc-thymulin by the thymus and in this form is a critical hormonal regulator of cellular immunity. In the absence of serum, zinc…”
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Guanosine 3′:5′-Cyclic Monophosphate: A Possible Intracellular Mediator of Mitogenic Influences in Lymphocytes by Hadden, John W., Hadden, Elba M., Haddox, Mari K., Goldberg, Nelson D.

“…Adenosine 3′:5′-cyclic monophosphate (cyclic AMP) has been shown to have an antimitotic role in various cell types, and it has been hypothesized that a…”
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Evidence for Cyclic GMP and Calcium Mediation of Lymphocyte Activation by Mitogens by Coffey, Ronald G, Hadden, Elba M, Hadden, John W

“…The results of 47 experiments indicate that the lectin mitogens, PHA and Con A, increase cyclic GMP (cGMP) levels in human peripheral blood lymphocytes and…”
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Levamisole and inosiplex: antiviral agents with immunopotentiating action by Hadden, J W, Lopez, C, O'Reilly, R J, Hadden, E M

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Interleukins and contrasuppression induce immune regression of head and neck cancer by Hadden, J W, Endicott, J, Baekey, P, Skipper, P, Hadden, E M

“…Metastatic squamous cell head and neck cancer was treated in four patients with low-dose cyclophosphamide (to reduce suppressor T-cell activity), indomethacin…”
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The Induction of Macrophage Proliferation in Vitro by a Lymphocyte-Produced Factor by Hadden, John W, Sadlik, John R, Hadden, Elba M

“…The studies presented indicate that sensitized guinea pig lymph node lymphocytes release on exposure to antigen a soluble mediator of 35 to 70,000 daltons,…”
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Direct Action of Insulin on Plasma Membrane ATPase Activity in Human Lymphocytes by HADDEN, JOHN W, HADDEN, ELBA M, WILSON, EDWIN E, GOOD, ROBERT A, COFFEY, RONALD G

“…LITTLE is known about the effects of insulin on lymphocytes. Helmreich and Eisen1 concluded that it has insignificant effects, but others2-5 have made a case…”
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Thymic involution in aging. Prospects for correction by Hadden, J W, Malec, P H, Coto, J, Hadden, E M

“…The thymus produces several putative thymic hormones: thymosin alpha 1, thymulin, and thymopoietin, which have been reported to circulate and to act on both…”
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A pituitary factor induces thymic epithelial cell proliferation in vitro by Hadden, J W, Galy, A, Chen, H, Hadden, E M

“…Human thymic epithelial cells (TEC) were grown in culture and confirmed to be keratin positive (98-100%) and epidermal growth factor (EGF) responsive. Bovine…”
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Phorbol myristate acetate: a mitogen selective for a T-lymphocyte subpopulation by Touraine, J L, Hadden, J W, Touraine, F, Hadden, E M, Estensen, R, Good, R A

“…Phorbol myristate acetate (pma) is a potent mitogen for human peripheral blood lymphocytes (PBL) comparable to phytohemagglutinin (PHA) in potency…”
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Effects of cytokines on human thymic epithelial cells in culture: IL1 induces thymic epithelial cell proliferation and change in morphology by Galy, A H, Hadden, E M, Touraine, J L, Hadden, J W

“…The role of thymic epithelium in T cell development has given rise to a number of studies, but less information is available concerning the factors regulating…”
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Prolactin and known modulators of rat splenocytes activate nuclear protein kinase C by Russell, D H, Zorn, N E, Buckley, A R, Crowe, P D, Sauro, M D, Hadden, E M, Farese, R V, Laird, 2nd, H E

“…Prolactin (PRL) and other trophic factors rapidly activate a nuclear pool(s) of protein kinase C (nPKC) in purified splenocyte nuclei. The PRL also enhanced…”
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Lymphocyte blast transformation. I. Demonstration of adrenergic receptors in human peripheral lymphocytes by Hadden, J W, Hadden, E M, Middleton, Jr, E

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Methyl inosine monophosphate: a potential immunotherapeutic for early human immunodeficiency virus (HIV) infection by Hadden, J W, Ongradi, J, Specter, S, Nelson, R, Sosa, M, Monell, C, Strand, M, Giner-Sorolla, A, Hadden, E M

“…MIMP is a new thymomimetic purine under development for immunorestorative therapy. Lymphocytes were obtained from eight patients with acquired immunodeficiency…”
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Potentiation of immune responses in mice by a new inosine derivative--methyl inosine monophosphate (MIMP) by Sosa, M, Saha, A R, Wang, Y, Coto, J, Giner-Sorolla, A, Hadden, E M, Hadden, J W

“…Inosine 5'-methyl monophosphate (MIMP) is a new immunomodulator designed to improve upon the activity of other thymomimetic purines. In Balb/c mice, MIMP was…”
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Cyclic nucleotides and calcium in lymphocyte regulation and activation by Hadden, J W, Coffey, R G, Ananthakrishnan, R, Hadden, E M

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Effects of Concanavalin A and a Succinylated Derivative on Lymphocyte Proliferation and Cyclic Nucleotide Levels by Hadden, John W., Hadden, Elba M., Sadlik, John R., Coffey, Ronald G.

“…To better define cell surface-related changes involved in lymphocyte activation, we studied native concanavalin A (Con A) and succinylated concanavalin A…”
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Interleukin II increases cyclic GMP levels in immature thymocytes and mitogen-primed T-lymphocytes by Hadden, J W, Hadden, E M, Coffey, R G

“…Interleukin II, also called T-cell growth factor, induces proliferation of immature peanut agglutinin positive murine thymocytes (PNA+) and renders them…”
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The comparative effects of isoprinosine, levamisole, muramyl dipeptide and SM1213 on lymphocyte and macrophage proliferation and activation in vitro by Hadden, J W, Englard, A, Sadlik, J R, Hadden, E M

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Therapy of secondary T-cell immunodeficiencies with biological substances and drugs by Hadden, J W, Hadden, E M

“…Thymus-dependent (T) lymphocyte defects are common in cancer. Recent advances in the understanding of the regulation of T-cell development by biologicals and…”
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