Search Results - "Haddad, Helena"
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Subcutaneous nanotherapy repurposes the immunosuppressive mechanism of rapamycin to enhance allogeneic islet graft viability
Published in Nature nanotechnology (01-03-2022)“…Standard oral rapamycin (that is, Rapamune) administration is plagued by poor bioavailability and broad biodistribution. Thus, this pleotropic mammalian target…”
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Clinical Relevance of Pre-Existing and Treatment-Induced Anti-Poly(Ethylene Glycol) Antibodies
Published in Regenerative engineering and translational medicine (2022)“…Poly(ethylene glycol) (PEG) is a nontoxic, hydrophilic polymer that is often covalently attached to proteins, drugs, tissues, or materials; a procedure…”
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Multi-Target Peptide Nanofiber Immunotherapy Diminishes Complement Anaphylatoxin Activity in Acute Inflammation
Published in Advanced healthcare materials (30-10-2024)“…The anaphylatoxins C3a and C5a are products of the complement cascade that play important and interrelated roles in health and disease. Both are potential…”
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Expanding opportunities to engineer mucosal vaccination with biomaterials
Published in Biomaterials science (28-02-2023)“…Mucosal vaccines are receiving increasing interest both for protecting against infectious diseases and for inducing therapeutic immune responses to treat…”
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Personality Impairment in Children and Adolescents with ADHD
Published in Paidéia cadernos de Psicologia e Educação (2021)“…Abstract Attention deficit hyperactivity disorder in children and adolescents manifests itself in a heterogeneous manner as regards personality aspects. This…”
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Active immunotherapy for C5a-mediated inflammation using adjuvant-free self-assembled peptide nanofibers
Published in Acta biomaterialia (15-04-2024)“…The terminal protein in the complement cascade C5a is a potent inflammatory molecule and chemoattractant that is involved in the pathology of multiple…”
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209.8: Subcutaneous Nanotherapy Repurposes the Immunosuppressive Mechanism of Rapamycin to Enhance Allogeneic Islet Graft Viability
Published in Transplantation (01-12-2021)Get full text
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Treatment of Inflammatory Bowel Disease using phosphorylcholine-presenting nanofibers engaging natural antibody responses
Published in Nature biomedical engineering (27-11-2023)“…Inflammatory bowel disease (IBD) is a chronic disease that lacks a long-lasting and broadly effective therapy. Preexisting natural antibodies targeting the…”
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Supramolecular Peptide Self-Assemblies Facilitate Oral Immunization
Published in ACS biomaterials science & engineering (13-05-2024)“…Oral immunization is a promising strategy for preventing and treating gastrointestinal (GI) infections and diseases, as it allows for direct access to the…”
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Engaging natural antibody responses for the treatment of inflammatory bowel disease via phosphorylcholine-presenting nanofibres
Published in Nature biomedical engineering (01-05-2024)“…Inflammatory bowel disease lacks a long-lasting and broadly effective therapy. Here, by taking advantage of the anti-infection and anti-inflammatory properties…”
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11
Risk of aspiration pneumonia after an epileptic seizure: a retrospective analysis of 1634 adult patients
Published in Epilepsy & behavior (01-08-2004)“…We reviewed the incidence of aspiration pneumonia secondary to seizures in three populations of patients with chronic epilepsy: 733 outpatients seen in an…”
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Personality Impairment in Children and Adolescents with ADHD/Deterioro de la Personalidad en Ninos y Adolescentes con TDAH/Comprometimento da Personalidade em Criancas e Adolescentes com TDAH
Published in Paidéia cadernos de Psicologia e Educação (01-01-2021)“…Attention deficit hyperactivity disorder in children and adolescents manifests itself in a heterogeneous manner as regards personality aspects. This study…”
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Behaviors mimicking seizures in institutionalized individuals with multiple disabilities and epilepsy: a video-EEG study
Published in Epilepsy & behavior (01-06-2002)“…We reviewed 824 video-EEG telemetry requests of institutionalized patients with epilepsy, searching for evaluations of “new seizure types” identified by staff…”
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Personality Impairment in Children and Adolescents with ADHD/Deterioro de la Personalidad en Ninos y Adolescentes con TDAH/Comprometimento da Personalidade em Criancas e Adolescentes com TDAH
Published in Paidéia cadernos de Psicologia e Educação (01-01-2021)“…Attention deficit hyperactivity disorder in children and adolescents manifests itself in a heterogeneous manner as regards personality aspects. This study…”
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15
Progressive scoliosis in early, non-progressive CNS injuries: role of axial muscles
Published in Brain injury (1999)“…Forty three patients with progressive neurological deficits involving axial musculature, starting 3-6 years after non progressive brain injuries insults are…”
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Surgical correction of scoliosis in patients with generalized seizures : Risk of vertebral body fracture
Published in Spine (Philadelphia, Pa. 1976) (01-05-1998)“…A retrospective evaluation of the outcome of surgical management of progressive scoliosis in institutionalized patients with frequent, uncontrolled,…”
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