Search Results - "Haddad, G"

Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development by Trujillo, Cleber A., Gao, Richard, Negraes, Priscilla D., Gu, Jing, Buchanan, Justin, Preissl, Sebastian, Wang, Allen, Wu, Wei, Haddad, Gabriel G., Chaim, Isaac A., Domissy, Alain, Vandenberghe, Matthieu, Devor, Anna, Yeo, Gene W., Voytek, Bradley, Muotri, Alysson R.

“…Structural and transcriptional changes during early brain maturation follow fixed developmental programs defined by genetics. However, whether this is true for…”
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Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 Å by Flores, Jonathan A., Haddad, Bassam G., Dolan, Kimberly A., Myers, Janette B., Yoshioka, Craig C., Copperman, Jeremy, Zuckerman, Daniel M., Reichow, Steve L.

“…Gap junctions establish direct pathways for cells to transfer metabolic and electrical messages. The local lipid environment is known to affect the structure,…”
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Investigating the neurobiology of maternal opioid use disorder and prenatal opioid exposure using brain organoid technology by Dwivedi, Ila, Haddad, Gabriel G

“…Over the past two decades, Opioid Use Disorder (OUD) among pregnant women has become a major global public health concern. OUD has been characterized as a…”
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A Boolean approach for novel hypoxia-related gene discovery by Stobdan, Tsering, Sahoo, Debashis, Haddad, Gabriel G

“…Hypoxia plays a major role in the etiology and pathogenesis of most of the leading causes of morbidity and mortality, whether cardiovascular diseases, cancer,…”
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Hepatitis E Virus Lifecycle and Identification of 3 Forms of the ORF2 Capsid Protein by Montpellier, Claire, Wychowski, Czeslaw, Sayed, Ibrahim M., Meunier, Jean-Christophe, Saliou, Jean-Michel, Ankavay, Maliki, Bull, Anne, Pillez, André, Abravanel, Florence, Helle, François, Brochot, Etienne, Drobecq, Hervé, Farhat, Rayan, Aliouat-Denis, Cécile-Marie, Haddad, Juliano G., Izopet, Jacques, Meuleman, Philip, Goffard, Anne, Dubuisson, Jean, Cocquerel, Laurence

“…Hepatitis E virus (HEV) infection is a major cause of acute hepatitis worldwide. Approximately 2 billion people live in areas endemic for HEV and are at risk…”
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The evolution of acute lymphoblastic leukemia research and therapy at MD Anderson over four decades by Jabbour, Elias, Short, Nicholas J, Jain, Nitin, Haddad, Fadi G, Welch, Mary Alma, Ravandi, Farhad, Kantarjian, Hagop

“…Progress in the research and therapy of adult acute lymphoblastic leukemia (ALL) is accelerating. This analysis summarizes the data derived from the clinical…”
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PD-L1 protein expression by Combined Positive Score (CPS) in patients with muscle invasive or advanced urothelial carcinoma: a single institution experience by Nasr, Sarah, Haddad, Fadi G, Khazen, Joseph, Kattan, Joseph, Trak-Smayra, Viviane

“…Abstract Introduction Immune checkpoint inhibitors have revolutionized the treatment of patients with advanced urothelial carcinoma (UC) in the frontline and…”
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Effects of oxygen on growth and size: synthesis of molecular, organismal, and evolutionary studies with Drosophila melanogaster by Harrison, Jon F, Haddad, Gabriel G

“…Drosophila melanogaster is a model genetic organism with an exceptional hypoxia tolerance relative to mammals. Forward genetic, microarray, and P-element…”
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A data-driven model for early prediction of need for invasive mechanical ventilation in pediatric intensive care unit patients by Bose, Sanjukta N, Defante, Andrew, Greenstein, Joseph L, Haddad, Gabriel G, Ryu, Julie, Winslow, Raimond L

“…Acute respiratory failure is a life-threatening clinical outcome in critically ill pediatric patients. In severe cases, patients can require mechanical…”
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Protective role of estrogen against excessive erythrocytosis in Monge’s disease by Azad, Priti, Villafuerte, Francisco C., Bermudez, Daniela, Patel, Gargi, Haddad, Gabriel G.

“…Monge’s disease (chronic mountain sickness (CMS)) is a maladaptive condition caused by chronic (years) exposure to high-altitude hypoxia. One of the defining…”
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Intermittent Hypoxia and Hypercapnia Accelerate Atherosclerosis, Partially via Trimethylamine-Oxide by Xue, Jin, Zhou, Dan, Poulsen, Orit, Imamura, Toshihiro, Hsiao, Yu-Hsin, Smith, Travis H, Malhotra, Atul, Dorrestein, Pieter, Knight, Rob, Haddad, Gabriel G

“…Obstructive sleep apnea (OSA) is a common disorder characterized by intermittent hypoxia and hypercapnia (IHC) during sleep. OSA has been shown to be a risk…”
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EP04.04: How to prove glossoptosis in Pierre Robin syndrome diagnosis: sagittal evaluation of pharynx helped with epiglottis by Develay‐Morice, J., Frandji, N., Lesieur, E., Haddad, G., Bretelle, F.

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Alzheimer's disease like neuropathology in Down syndrome cortical organoids by Zhao, Helen H, Haddad, Gabriel G

“…Down syndrome (DS) is a genetic disorder with an extra copy of chromosome 21 and DS remains one of the most common causes of intellectual disabilities in…”
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VP13.17: Cystic saccrococcygeal tumour by Develay‐Morice, J., Bengherbia, A., Haddad, G.

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High fat diet induces sex-specific differential gene expression in Drosophila melanogaster by Stobdan, Tsering, Sahoo, Debashis, Azad, Priti, Hartley, Iain, Heinrichsen, Erilynn, Zhou, Dan, Haddad, Gabriel G

“…Currently about 2 billion adults globally are estimated to be overweight and ~13% of them are obese. High fat diet (HFD) is one of the major contributing…”
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Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B by Azad, Priti, Zhou, Dan, Tu, Hung-Chi, Villafuerte, Francisco C, Traver, David, Rana, Tariq M, Haddad, Gabriel G

“…Excessive erythrocytosis (EE) is a major hallmark of patients suffering from chronic mountain sickness (CMS, also known as Monge's disease) and is responsible…”
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Alcoholic cardiomyopathy: The heart got NRF by Haddad, G

“…On the contrary, HA increased H2O2 levels (as well as SOD-3 activity) and reduced the Akt, NF-?B, FOXO-1 and NRF1/2 gene expressions which translated into…”
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The Pupa Stage Is the Most Sensitive to Hypoxia in Drosophila melanogaster by Stobdan, Tsering, Wen, Nicholas J, Lu-Bo, Ying, Zhou, Dan, Haddad, Gabriel G

“…Hypoxia not only plays a critical role in multiple disease conditions; it also influences the growth and development of cells, tissues and organs. To identify…”
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Ayapana triplinervis Essential Oil and Its Main Component Thymohydroquinone Dimethyl Ether Inhibit Zika Virus at Doses Devoid of Toxicity in Zebrafish by Haddad, Juliano G, Picard, Morgane, Bénard, Sebastien, Desvignes, Claire, Desprès, Philippe, Diotel, Nicolas, El Kalamouni, Chaker

“…Zika virus (ZIKV) is an emerging mosquito-borne virus of medical concern. ZIKV infection may represent a serious disease, causing neonatal microcephaly and…”
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SLC22 Transporters in the Fly Renal System Regulate Response to Oxidative Stress In Vivo by Zhang, Patrick, Azad, Priti, Engelhart, Darcy C, Haddad, Gabriel G, Nigam, Sanjay K

“…Several SLC22 transporters in the human kidney and other tissues are thought to regulate endogenous small antioxidant molecules such as uric acid,…”
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