Search Results - "Hadar, Ravit"
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Prevention of schizophrenia deficits via non-invasive adolescent frontal cortex stimulation in rats
Published in Molecular psychiatry (01-04-2020)“…Schizophrenia is a severe neurodevelopmental psychiatric affliction manifested behaviorally at late adolescence/early adulthood. Current treatments comprise…”
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Using cortical non-invasive neuromodulation as a potential preventive treatment in schizophrenia - A review
Published in Brain stimulation (01-05-2021)“…Evidence suggests that schizophrenia constitutes a neurodevelopmental disorder, characterized by a gradual emergence of behavioral and neurobiological…”
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Subthalamic nucleus but not entopeduncular nucleus deep brain stimulation enhances neurogenesis in the SVZ-olfactory bulb system of Parkinsonian rats
Published in Frontiers in cellular neuroscience (30-04-2024)“…Deep brain stimulation (DBS) is a highly effective treatment option in Parkinson's disease. However, the underlying mechanisms of action, particularly effects…”
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Response to Deep Brain Stimulation in Three Brain Targets with Implications in Mental Disorders: A PET Study in Rats
Published in PloS one (29-12-2016)“…To investigate metabolic changes in brain networks by deep brain stimulation (DBS) of the medial prefrontal cortex (mPFC), nucleus accumbens (NAcc) and…”
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Memory formation in reversal learning of the honeybee
Published in Frontiers in behavioral neuroscience (13-12-2010)“…In reversal learning animals are first trained with a differential learning protocol, where they learn to respond to a reinforced odor (CS+) and not to respond…”
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STATE-DEPENDENT EFFECT OF NON-INVASIVE BRAIN STIMULATION ON NEUROANATOMY AND BEHAVIOR
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Supplement Treatment with NAC and Omega-3 Polyunsaturated Fatty Acids during Pregnancy Partially Prevents Schizophrenia-Related Outcomes in the Poly I:C Rat Model
Published in Antioxidants (09-05-2023)“…Heightened levels of inflammation and oxidative stress are thought to be involved in the pathophysiology of schizophrenia. We aimed to assess whether intake of…”
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Enhanced UV-Reflection Facilitated a Shift in the Pollination System of the Red Poppy, Papaver rhoeas (Papaveraceae)
Published in Plants (Basel) (22-07-2020)“…Evolutionary change is considered a major factor influencing the invasion of new habitats by plants. Yet, evidence on how such modifications promote range…”
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Anti-Anhedonic Effect of Deep Brain Stimulation of the Prefrontal Cortex and the Dopaminergic Reward System in a Genetic Rat Model of Depression: An Intracranial Self-Stimulation Paradigm Study
Published in Brain stimulation (2014)“…Abstract Background One of the two core symptoms of major depression (MD), whether uni- or bipolar, is the inability to experience pleasure, suggested to be…”
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Non-invasive modulation reduces repetitive behavior in a rat model through the sensorimotor cortico-striatal circuit
Published in Translational psychiatry (10-01-2018)“…Involuntary movements as seen in repetitive disorders such as Tourette Syndrome (TS) results from cortical hyperexcitability that arise due to…”
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Adolescent raloxifene treatment in females prevents cognitive deficits in a neurodevelopmental rodent model of schizophrenia
Published in Behavioural brain research (12-03-2023)“…The existence of sex differences in schizophrenia is a well documented phenomenon which led to the hypothesis that female sex hormones are neuroprotective and…”
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Minocycline rescues decrease in neurogenesis, increase in microglia cytokines and deficits in sensorimotor gating in an animal model of schizophrenia
Published in Brain, behavior, and immunity (01-05-2014)“…Abstract Adult neurogenesis in the hippocampus is impaired in schizophrenic patients and in an animal model of schizophrenia. Amongst a plethora of regulators,…”
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Deep brain stimulation improves behavior and modulates neural circuits in a rodent model of schizophrenia
Published in Experimental neurology (01-09-2016)“…Schizophrenia is a debilitating psychiatric disorder with a significant number of patients not adequately responding to treatment. Deep brain stimulation (DBS)…”
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Former Training Relieves the Later Development of Behavioral Inflexibility in an Animal Model Overexpressing the Dopamine Transporter
Published in Molecular neurobiology (01-12-2022)“…A range of dopamine-dominating neuropsychiatric disorders present with cognitive deficits. In accordance, the dopamine transporter overexpressing rat model…”
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Using a maternal immune stimulation model of schizophrenia to study behavioral and neurobiological alterations over the developmental course
Published in Schizophrenia research (01-08-2015)“…Abstract A growing body of evidence sheds light on the neurodevelopmental nature of schizophrenia with symptoms typically emerging during late adolescence or…”
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Deep brain stimulation during early adolescence prevents microglial alterations in a model of maternal immune activation
Published in Brain, behavior, and immunity (01-07-2017)“…Highlights • Microglia density in a MIA model is increased in hippocampus and nucleus accumbens. • Preventive DBS during adolescence halters microglia changes…”
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Choosing the Optimal Brain Target for Neuromodulation Therapies as Alcohol Addiction Progresses—Insights From Pre-Clinical Studies
Published in Current addiction reports (01-09-2020)“…Purpose of the Review Development of addiction involves a transition from reward-driven to habitual behavior, mediated by neuroplastic changes. Based on…”
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Adolescent raloxifene treatment in females prevents cognitive deficits in a neurodevelopmental rodent model of schizophrenia
Published in Behavioural brain research (12-03-2023)Get full text
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Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders
Published in Scientific reports (15-12-2016)“…The dopamine transporter (DAT) plays a pivotal role in maintaining optimal dopamine signaling. DAT-overactivity has been linked to various neuropsychiatric…”
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Testing different paradigms to optimize antidepressant deep brain stimulation in different rat models of depression
Published in Journal of psychiatric research (01-10-2016)“…Abstract Deep brain stimulation (DBS) of several targets induces beneficial responses in approximately 60% of patients suffering from treatment-resistant…”
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