Search Results - "Hackl, Matthias"

microRNAs as promising biomarkers of platelet activity in antiplatelet therapy monitoring by Krammer, Teresa L, Mayr, Manuel, Hackl, Matthias

“…Given the high morbidity and mortality of cardiovascular diseases (CVDs), novel biomarkers for platelet reactivity are urgently needed. Ischemic events in CVDs…”
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Real-time imaging of cGMP signaling shows pronounced differences between glomerular endothelial cells and podocytes by Rutkowski, Nelli, Görlitz, Frederik, Wiesner, Eva, Binz-Lotter, Julia, Feil, Susanne, Feil, Robert, Benzing, Thomas, Hackl, Matthias J.

“…Recent clinical trials of drugs enhancing cyclic guanosine monophosphate (cGMP) signaling for cardiovascular diseases have renewed interest in cGMP biology…”
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Circulating miRNAs in bone health and disease by Grillari, Johannes, Mäkitie, Riikka E., Kocijan, Roland, Haschka, Judith, Vázquez, David Carro, Semmelrock, Elisabeth, Hackl, Matthias

“…microRNAs have evolved as important regulators of multiple biological pathways essential for bone homeostasis, and microRNA research has furthered our…”
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Correlative multiphoton-STED microscopy of podocyte calcium levels and slit diaphragm ultrastructure in the renal glomerulus by Wiesner, Eva, Binz-Lotter, Julia, Hackl, Agnes, Unnersjö-Jess, David, Rutkowski, Nelli, Benzing, Thomas, Hackl, Matthias J.

“…In recent years functional multiphoton (MP) imaging of vital mouse tissues and stimulation emission depletion (STED) imaging of optically cleared tissues…”
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Differentially circulating miRNAs after recent osteoporotic fractures can influence osteogenic differentiation by Weilner, Sylvia, Skalicky, Susanna, Salzer, Benjamin, Keider, Verena, Wagner, Michael, Hildner, Florian, Gabriel, Christian, Dovjak, Peter, Pietschmann, Peter, Grillari-Voglauer, Regina, Grillari, Johannes, Hackl, Matthias

“…Abstract Osteoporosis is the consequence of altered bone metabolism resulting in the systemic reduction of bone strength and increased risk of fragility…”
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Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags by Hackl, Matthias J, Burford, James L, Villanueva, Karie, Lam, Lisa, Suszták, Katalin, Schermer, Bernhard, Benzing, Thomas, Peti-Peterdi, János

“…Matthias Hackl and his colleagues developed a new serial multiphoton microscopy approach to track migrating podocytes and parietal epithelial cells over time…”
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Injured Podocytes Are Sensitized to Angiotensin II-Induced Calcium Signaling by Binz-Lotter, Julia, Jüngst, Christian, Rinschen, Markus M, Koehler, Sybille, Zentis, Peter, Schauss, Astrid, Schermer, Bernhard, Benzing, Thomas, Hackl, Matthias J

“…Inhibition of angiotensin II (AngII) signaling, a therapeutic mainstay of glomerular kidney diseases, is thought to act primarily through regulating glomerular…”
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Impairment of Neurocognitive Functioning, Motor Performance, and Mood Stability in Hospitalized Patients With Euvolemic Moderate and Profound Hyponatremia by Suárez, Victor, Norello, Dario, Sen, Emel, Todorova, Polina, Hackl, Matthias J., Hüser, Christoph, Grundmann, Franziska, Kubacki, Torsten, Becker, Ingrid, Peri, Alessandro, Burst, Volker

“…The impact of chronic moderate and profound hyponatremia on neurocognitive performance, motor skills, and mood stability has not been investigated…”
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Intravital imaging of podocyte calcium in glomerular injury and disease by Burford, James L, Villanueva, Karie, Lam, Lisa, Riquier-Brison, Anne, Hackl, Matthias J, Pippin, Jeffrey, Shankland, Stuart J, Peti-Peterdi, János

“…Intracellular calcium ([Ca²⁺]i) signaling mediates physiological and pathological processes in multiple organs, including the renal podocyte; however, in vivo…”
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Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time by Feichtinger, Julia, Hernández, Inmaculada, Fischer, Christoph, Hanscho, Michael, Auer, Norbert, Hackl, Matthias, Jadhav, Vaibhav, Baumann, Martina, Krempl, Peter M., Schmidl, Christian, Farlik, Matthias, Schuster, Michael, Merkel, Angelika, Sommer, Andreas, Heath, Simon, Rico, Daniel, Bock, Christoph, Thallinger, Gerhard G., Borth, Nicole

“…ABSTRACT The most striking characteristic of CHO cells is their adaptability, which enables efficient production of proteins as well as growth under a variety…”
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The first decade of using multiphoton microscopy for high-power kidney imaging by Peti-Peterdi, János, Burford, James L, Hackl, Matthias J

“…In this review, we highlight the major scientific breakthroughs in kidney research achieved using multiphoton microscopy (MPM) and summarize the milestones in…”
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Circulating microRNAs in young individuals with long-duration type 1 diabetes in comparison with healthy controls by Swolin-Eide, Diana, Forsander, Gun, Pundziute Lyckå, Auste, Novak, Daniel, Grillari, Johannes, Diendorfer, Andreas B., Hackl, Matthias, Magnusson, Per

“…MicroRNAs (miRNAs) are short non-coding RNAs that are involved in post-transcriptional control of gene expression and might be used as biomarkers for…”
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Muscle-Specific Micro-Ribonucleic Acids miR-1-3p, miR-133a-3p, and miR-133b Reflect Muscle Regeneration After Single-Dose Zoledronic Acid Following Rotator Cuff Repair in a Rodent Chronic Defect Model by Schanda, Jakob E., Heher, Philipp, Weigl, Moritz, Drechsler, Susanne, Schädl, Barbara, Prueller, Johanna, Kocijan, Roland, Heuberer, Philipp R., Hackl, Matthias, Muschitz, Christian, Grillari, Johannes, Redl, Heinz, Feichtinger, Xaver, Fialka, Christian, Mittermayr, Rainer

“…Background: Zoledronic acid improves bone microarchitecture and biomechanical properties after chronic rotator cuff repair (RCR) in rats. Besides the positive…”
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Candidate Signature miRNAs from Secreted miRNAome of Human Lung Microvascular Endothelial Cells in Response to Different Oxygen Conditions: A Pilot Study by Schaubmayr, Wolfgang, Hackl, Matthias, Pultar, Marianne, Ghanim, Bahil D, Klein, Klaus U, Schmid, Johannes A, Mohr, Thomas, Tretter, Verena

“…Oxygen conditions in the lung determine downstream organ functionality by setting the partial pressure of oxygen, regulating the redox homeostasis and by…”
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SVF-derived extracellular vesicles carry characteristic miRNAs in lipedema by Priglinger, Eleni, Strohmeier, Karin, Weigl, Moritz, Lindner, Carolin, Auer, Daniela, Gimona, Mario, Barsch, Martin, Jacak, Jaroslaw, Redl, Heinz, Grillari, Johannes, Sandhofer, Matthias, Hackl, Matthias, Wolbank, Susanne

“…Lipedema is a chronic, progressive disease of adipose tissue with lack of consistent diagnostic criteria. The aim of this study was a thorough comparative…”
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Exosomal miRNAs from Prostate Cancer Impair Osteoblast Function in Mice by Furesi, Giulia, de Jesus Domingues, Antonio Miguel, Alexopoulou, Dimitra, Dahl, Andreas, Hackl, Matthias, Schmidt, Johannes R, Kalkhof, Stefan, Kurth, Thomas, Taipaleenmäki, Hanna, Conrad, Stefanie, Hofbauer, Christine, Rauner, Martina, Hofbauer, Lorenz C

“…Prostate cancer (PCa) is the most frequent malignancy in older men with a high propensity for bone metastases. Characteristically, PCa causes osteosclerotic…”
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MicroRNAs and toxicology: A love marriage by Schraml, Elisabeth, Hackl, Matthias, Grillari, Johannes

“…With the dawn of personalized medicine, secreted microRNAs (miRNAs) have come into the very focus of biomarker development for various diseases. MiRNAs fulfil…”
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MicroRNA Expression Profiling in Porcine Liver, Jejunum and Serum upon Dietary DON Exposure Reveals Candidate Toxicity Biomarkers by Segura-Wang, Maia, Grenier, Bertrand, Ilic, Suzana, Ruczizka, Ursula, Dippel, Maximiliane, Bünger, Moritz, Hackl, Matthias, Nagl, Veronika

“…Deoxynivalenol (DON), a frequent mycotoxin worldwide, impairs human and animal health. The response of microRNAs, small non-coding RNAs, to DON has been…”
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Biotransformation of the Mycotoxin Zearalenone to its Metabolites Hydrolyzed Zearalenone (HZEN) and Decarboxylated Hydrolyzed Zearalenone (DHZEN) Diminishes its Estrogenicity In Vitro and In Vivo by Fruhauf, Sebastian, Novak, Barbara, Nagl, Veronika, Hackl, Matthias, Hartinger, Doris, Rainer, Valentina, Labudová, Silvia, Adam, Gerhard, Aleschko, Markus, Moll, Wulf-Dieter, Thamhesl, Michaela, Grenier, Bertrand

“…Zearalenone (ZEN)-degrading enzymes are a promising strategy to counteract the negative effects of this mycotoxin in livestock. The reaction products of such…”
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Investigation of MicroRNA Biomarkers in Equine Distal Interphalangeal Joint Osteoarthritis by Baker, Melissa E, Lee, Seungmee, Clinton, Michael, Hackl, Matthias, Castanheira, Catarina, Peffers, Mandy J, Taylor, Sarah E

“…Osteoarthritis of the equine distal interphalangeal joint is a common cause of lameness. MicroRNAs from biofluids are promising biomarkers and therapeutic…”
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