Search Results - "Hackfort, Bryan T."

Therapeutic Effects of Nrf2 Activation by Bardoxolone Methyl in Chronic Heart Failure by Tian, Changhai, Gao, Lie, Zhang, Andi, Hackfort, Bryan T, Zucker, Irving H

“…Oxidative stress plays an important role in the pathogenesis of chronic heart failure (CHF) in many tissues. Increasing evidence suggests that systemic…”
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Exercise ameliorates high fat diet induced cardiac dysfunction by increasing interleukin 10 by Kesherwani, Varun, Chavali, Vishalakshi, Hackfort, Bryan T, Tyagi, Suresh C, Mishra, Paras K

“…Increasing evidence suggests that a sedentary lifestyle and a high fat diet (HFD) leads to cardiomyopathy. Moderate exercise ameliorates cardiac dysfunction,…”
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Restoration of normal blood flow in atherosclerotic arteries promotes plaque stabilization by Schake, Morgan A., McCue, Ian S., Curtis, Evan T., Ripperda, Thomas J., Harvey, Samuel, Hackfort, Bryan T., Fitzwater, Anna, Chatzizisis, Yiannis S., Kievit, Forrest M., Pedrigi, Ryan M.

“…Blood flow is a key regulator of atherosclerosis. Disturbed blood flow promotes atherosclerotic plaque development, whereas normal blood flow protects against…”
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A Link Between Methylglyoxal and Heart Failure During HIV-1 Infection by Dash, Prasanta K, Alomar, Fadhel A, Cox, Jesse L, McMillan, JoEllyn, Hackfort, Bryan T, Makarov, Edward, Morsey, Brenda, Fox, Howard S, Gendelman, Howard E, Gorantla, Santhi, Bidasee, Keshore R

“…Early-onset heart failure (HF) continues to be a major cause of morbidity and mortality in people living with human immunodeficiency virus type one (HIV-1)…”
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Extracellular vesicular MicroRNA-27a contributes to cardiac hypertrophy in chronic heart failure by Tian, Changhai, Hu, Guoku, Gao, Lie, Hackfort, Bryan T., Zucker, Irving H.

“…Under stress, the heart undergoes extensive remodeling resulting in cardiac fibrosis and hypertrophy, ultimately contributing to chronic heart failure (CHF)…”
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Sympathoinhibition and vasodilation contribute to the acute hypotensive response of the superoxide dismutase mimic, MnTnBuOE-2-PyP5+, in hypertensive animals by Schlichte, Sarah L., Pekas, Elizabeth J., Bruett, Taylor J., Kosmacek, Elizabeth A., Hackfort, Bryan T., Rasmussen, Jordan M., Patel, Kaushik P., Park, Song-Young, Oberley-Deegan, Rebecca E., Zimmerman, Matthew C.

“…•BuOE rapidly and significantly decreases hypertensive blood pressure.•BuOE's hypotensive response is concomitant with sympathoinhibition and…”
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Overexpression of Skeletal Muscle Nrf2 Protects Against Aging‐Associated Dysfunction in Skeletal Muscle and Heart by Gao, Lie, Wang, Lucas, Hackfort, Bryan T., Zucker, Irving H.

“…Introduction The nuclear factor erythroid 2–related factor 2 (Nrf2) is a master transcription factor governing hundreds of genes coding proteins involved in…”
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Emerging role of hydrogen sulfide-microRNA crosstalk in cardiovascular diseases by Hackfort, Bryan T, Mishra, Paras K

“…Despite an obnoxious smell and toxicity at a high dose, hydrogen sulfide (H2S) is emerging as a cardioprotective gasotransmitter. H2S mitigates pathological…”
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Upregulating Nrf2 in the RVLM ameliorates sympatho-excitation in mice with chronic heart failure by Ma, Anyun, Hong, Juan, Shanks, Julia, Rudebush, Tara, Yu, Li, Hackfort, Bryan T, Wang, Hanjun, Zucker, Irving H, Gao, Lie

“…Nuclear factor E2-related factor 2 (Nrf2) is a key transcription factor that maintains redox homeostasis by governing a broad array of antioxidant genes in…”
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Macrophage depletion in stellate ganglia alleviates cardiac sympathetic overactivation and ventricular arrhythmogenesis by attenuating neuroinflammation in heart failure by Zhang, Dongze, Hu, Wenfeng, Tu, Huiyin, Hackfort, Bryan T., Duan, Bin, Xiong, Wanfen, Wadman, Michael C., Li, Yu-Long

“…Cardiac sympathetic overactivation is involved in arrhythmogenesis in patients with chronic heart failure (CHF). Inflammatory infiltration in the stellate…”
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Inhibition of N-type calcium channels in cardiac sympathetic neurons attenuates ventricular arrhythmogenesis in heart failure by Zhang, Dongze, Tu, Huiyin, Wang, Chaojun, Cao, Liang, Hu, Wenfeng, Hackfort, Bryan T, Muelleman, Robert L, Wadman, Michael C, Li, Yu-Long

“…Abstract Aims Cardiac sympathetic overactivation is an important trigger of ventricular arrhythmias in patients with chronic heart failure (CHF). Our previous…”
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Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy by Kar, Sumit, Shahshahan, Hamid R, Hackfort, Bryan T, Yadav, Santosh K, Yadav, Roopali, Kambis, Tyler N, Lefer, David J, Mishra, Paras K

“…Obesity increases the risk of developing diabetes and subsequently, diabetic cardiomyopathy (DMCM). Reduced cardioprotective antioxidant hydrogen sulfide (H S)…”
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HIV-1-Associated Left Ventricular Cardiac Dysfunction in Humanized Mice by Dash, Prasanta K., Alomar, Fadhel A., Hackfort, Bryan T., Su, Hang, Conaway, Amy, Poluektova, Larisa Y, Gendelman, Howard E., Gorantla, Santhi, Bidasee, Keshore R.

“…The molecular cause(s) for early onset heart failure in people living with HIV-1 infection (PLWH) remains poorly defined. Herein, longitudinal echocardiography…”
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Cigarette smoke-induced effects on bone marrow B-cell subsets and CD4+:CD8+ T-cell ratios are reversed by smoking cessation: Influence of bone mass on immune cell response to and recovery from smoke exposure by Fusby, Jenny S., Kassmeier, Michele D., Palmer, Victoria L., Perry, Greg A., Anderson, Dirk K., Hackfort, Bryan T., Alvarez, Gwen K., Cullen, Diane M., Akhter, Mohammed P., Swanson, Patrick C.

“…Cigarette smoking adversely affects the immune system, and is a risk factor for developing osteoporosis. How smoking contributes to osteoporosis is unclear,…”
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Increased circadian variations in chemoreflex sensitivity in chronic heart failure by Lewis, Robert, Hackfort, Bryan T., Schultz, Harold

“…Abstract only Respiratory function follows a circadian pattern, and rhythmic changes in carotid body sensitivity to blood gases may contribute to these…”
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Myocardial Oxygen Saturation Measured by Photoacoustic EKV Imaging by Hackfort, Bryan T., Chalise, Upendra, Daseke, Michael J., Lindsey, Merry L.

“…Abstract only Cardiac remodeling following myocardial infarction (MI) leads to structural and vascular changes in the myocardium. To better understand the…”
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Eight weeks of slow deep breathing training alters cardiorespiratory function and improves functional exercise capacity in chronic heart failure patients by Lewis, Robert, Seo, Yaewon, Hackfort, Bryan T., Pozehl, Bunny, Schultz, Harold D.

“…Patients with chronic heart failure (CHF) display autonomic imbalance characterized by excessive sympathoexcitation and reduced vagal outflow. Respiratory…”
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Diaphragm Muscle Function and Antioxidant Levels in Chronic Heart Failure by Hackfort, Bryan T, Lewis, Robert, Gao, Lie, Zucker, Irving H, Schultz, Harold D

“…Abstract only Nearly 5.7 million adults in the United States have chronic heart failure (CHF). CHF is associated with dyspnea and impaired diaphragm function…”
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Sympathoinhibition and Vasodilation Contribute to the Acute Hypotensive Response of the Superoxide Dismutase Mimic, MnTnBuOE-2-PyP 5+ , in Hypertensive Animals by Schlichte, Sarah L, Pekas, Elizabeth J, Bruett, Taylor J, Kosmacek, Elizabeth A, Hackfort, Bryan T, Rasmussen, Jordan M, Patel, Kaushik P, Park, Song-Young, Oberley-Deegan, Rebecca E, Zimmerman, Matthew C

“…The pathogenesis of hypertension has been linked to excessive levels of reactive oxygen species (ROS), particularly superoxide (O ), in multiple tissues and…”
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