Search Results - "Hacker, Hans Jörg"
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Inhibition of Hepatitis B Virus Replication by Drug-Induced Depletion of Nucleocapsids
Published in Science (American Association for the Advancement of Science) (07-02-2003)“…Chronic hepatitis B virus (HBV) infection is a major cause of liver disease. Only interferon-α and the nucleosidic inhibitors of the viral polymerase, 3TC and…”
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2
Hyperproliferative Hepatocellular Alterations after Intraportal Transplantation of Thyroid Follicles
Published in The American journal of pathology (2000)“…The thyroid hormone 3,5,3′-triiodo- l-thyronine (T3) is a strong direct hepatocyte mitogen in vivo. The effects of T3 resemble those of peroxisome…”
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3
Hepatocellular Alterations after Intraportal Transplantation of Ovarian Tissue in Ovariectomized Rats
Published in The American journal of pathology (01-05-2000)“…The mechanisms of hepatocarcinogenesis by certain synthetic estrogens seem to involve both nongenotoxic and indirect genotoxic effects. However, the natural…”
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4
Metabolic activation of aflatoxin B1 to aflatoxin B1‐8,9‐epoxide in woodchucks undergoing chronic active hepatitis
Published in International journal of cancer (14-11-1997)“…Chronic hepatitis B virus infection as well as consumption of food contaminated with the mycotoxin aflatoxin B1 are considered to be 2 major risk factors for…”
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5
EblacZ tumor dormancy in bone marrow and lymph nodes : Active control of proliferating tumor cells by CD8+ immune T cells
Published in Cancer research (Chicago, Ill.) (01-12-1998)“…A well-defined lacZ gene tagged DBA/2 lymphoma (EblacZ) was used to examine the role of host immune responses in controlling tumor dissemination and…”
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Patterns of circulating hepatitis B virus serum nucleic acids during lamivudine therapy
Published in Journal of medical virology (01-09-2003)“…We examined whether lamivudine treatment, in addition to the rapid decline of HBV serum DNA described in a large number of laboratories, causes changes in…”
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7
Phenotypic instability in focal and nodular lesions induced in a short term system in the rat liver
Published in Carcinogenesis (New York) (1983)“…A comparative morphologic, morphometric and enzyme histochemical investigation of lesions induced by short-term application of N-nitrosomorpholine (NNM) and…”
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Differences between graft-versus-leukemia and graft-versus-host reactivity. I. Interaction of donor immune T cells with tumor and/or host cells
Published in Blood (15-03-1997)“…Graft-versus-leukemia (GVL) and Graft-versus-host (GVH) reactions were compared after systemic transfer of allogeneic antitumor immune T lymphocytes from…”
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Localization of estrogen receptors in interstitial cells of hamster kidney and in estradiol-induced renal tumors as evidence of the mesenchymal origin of this neoplasm
Published in Cancer research (Chicago, Ill.) (15-11-1993)“…The mechanism of estrogen-induced and -dependent kidney carcinogenesis in Syrian hamsters and the cell of origin of the tumor are not well understood; they…”
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Histochemical profile of mouse hepatocellular adenomas and carcinomas induced by a single dose of diethylnitrosamine
Published in Cancer research (Chicago, Ill.) (01-04-1991)“…In continuation of earlier studies on murine neoplastic liver lesions, we characterized by histochemical methods the phenotype of hepatocellular adenomas and…”
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Hepatocellular glycogenosis and hepatocarcinogenesis
Published in Biochimica et biophysica acta (06-05-1980)Get more information
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12
Persistence of the cholangiocellular and hepatocellular lesions observed in rats fed a choline-deficient/DL-ethionine-supplemented diet
Published in Carcinogenesis (New York) (01-02-1992)“…Male outbred Sprague-Dawley rats were fed a choline-deficient diet containing 0.10% DL-ethionine (CDE) for 4, 6, 10, 14 or 22 weeks followed by a standard diet…”
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13
Histochemical analysis of the development of estradiol-induced kidney tumors in male Syrian hamsters
Published in Cancer research (Chicago, Ill.) (15-02-1988)“…Chronic administration of the estrogen 17 beta-estradiol induces kidney tumors in male Syrian hamsters within 6 months of initial exposure. Although these…”
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14
Histochemical characterization of focal hepatic lesions induced by single diethylnitrosamine treatment in infant mice
Published in Cancer research (Chicago, Ill.) (01-06-1985)“…Focal hepatocellular lesions, induced in our infant mouse system (15-day-old B6C3F1 mice) by a single carcinogenic dose of diethylnitrosamine (2.5 or 5.0…”
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Antivirals interacting with hepatitis B virus core protein and core mutations may misdirect capsid assembly in a similar fashion
Published in Biochemical pharmacology (15-12-2003)“…Recently, heteroarylpyrimidines (HAP) have been identified as potent inhibitors of capsid maturation. Here we discuss the HAP mode of action comparing the…”
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Hepatitis B virus X-DNA. A serum marker for early detection of resistance development during lamivudine therapy
Published in Annals of the New York Academy of Sciences (01-08-2008)“…HBV genome replication intermediates blocked at early stages of minus strand synthesis have been identified in a study on circulating DNA and RNA during…”
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17
Hepatitis B Virus X-DNA
Published in Annals of the New York Academy of Sciences (01-08-2008)“…HBV genome replication intermediates blocked at early stages of minus strand synthesis have been identified in a study on circulating DNA and RNA during…”
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18
Patterns of Circulating Hepatitis B Virus Serum Nucleic Acids during Lamivudine Therapy
Published in Annals of the New York Academy of Sciences (01-06-2004)“…: Lamivudine treatment of individuals with chronic HBV infection leads to a rapid decline of hepatitis B virus (HBV) serum DNA. Because HBV replication quickly…”
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Hepadnaviral hepatocarcinogenesis: in situ visualization of viral antigens, cytoplasmic compartmentation, enzymic patterns, and cellular proliferation in preneoplastic hepatocellular lineages in woodchucks
Published in Journal of hepatology (01-10-2000)“…Background/Aims: Hepadnaviral hepatocarcinogenesis induced in woodchucks with and without dietary aflatoxin B 1 has been established as an appropriate animal…”
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Detection of HBV RNA in serum of patients
Published in Methods in molecular medicine (2004)Get more information
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