Search Results - "Hack, V."

An open label, randomised controlled trial of rifapentine versus rifampicin based short course regimens for the treatment of latent tuberculosis in England: the HALT LTBI pilot study by Surey, J, Stagg, H R, Yates, T A, Lipman, M, White, P J, Charlett, A, Muñoz, L, Gosce, L, Rangaka, M X, Francis, M, Hack, V, Kunst, H, Abubakar, I

“…Ending the global tuberculosis (TB) epidemic requires a focus on treating individuals with latent TB infection (LTBI) to prevent future cases. Promising trials…”
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Impairment of intestinal glutathione synthesis in patients with inflammatory bowel disease by Sido, B, Hack, V, Hochlehnert, A, Lipps, H, Herfarth, C, Dröge, W

“…Background—Reactive oxygen species contribute to tissue injury in inflammatory bowel disease (IBD). The tripeptide glutathione (GSH) is the most important…”
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PMN cell counts and phagocytic activity of highly trained athletes depend on training period by Hack, V, Strobel, G, Weiss, M, Weicker, H

“…We tested the hypothesis that polymorphonuclear leukocyte (PMN) cell counts and phagocytic activity determined by latex ingestion and superoxide anion…”
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Role of cysteine and glutathione in signal transduction, immunopathology and cachexia by Dröge, W., Hack, V., Breitkreutz, R., Holm, E., Shubinsky, G., Schmid, E., Galter, D.

“…Abnormally low plasma cystine levels have been found in the late asymptomatic stage of HIV infection and several other diseases associated with progressive…”
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Elevated venous glutamate levels in (pre)catabolic conditions result at least partly from a decreased glutamate transport activity by HACK, V, STÜTZ, O, KINSCHERF, R, SCHYKOWSKI, M, KELLERER, M, HOLM, E, DRÖGE, W

“…Abnormally high postabsorptive venous plasma glutamate levels have been reported for several diseases that are associated with a loss of body cell mass…”
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Low plasma glutamine in combination with high glutamate levels indicate risk for loss of body cell mass in healthy individuals : the effect of N-acetyl-cysteine by KINSCHERF, R, HACK, V, FISCHBACH, T, FRIEDMANN, B, WEISS, C, EDLER, L, BÄRTSCH, P, DRÖGE, W

“…Skeletal muscle catabolism, low plasma glutamine, and high venous glutamate levels are common among patients with cancer or human immunodeficiency virus…”
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The effect of maximal exercise on the activity of neutrophil granulocytes in highly trained athletes in a moderate training period by Hack, V, Strobel, G, Rau, J P, Weicker, H

“…Leucocyte cell counts and the phagocytic and chemotactic activities of neutrophil granulocytes were investigated in highly endurance-trained long-distance…”
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Effect of carnitine on muscular glutamate uptake and intramuscular glutathione in malignant diseases by BREITKREUTZ, R, BABYLON, A, HACK, V, SCHUSTER, K, TOKUS, M, BÖHLES, H, HAGMÜLLER, E, EDLER, L, HOLM, E, DRÖGE, W

“…Abnormally low intramuscular glutamate and glutathione (GSH) levels and/or a decreased muscular uptake of glutamate by the skeletal muscle tissue have…”
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Decreased plasma glutamine level and CD4+ T cell number in response to 8 wk of anaerobic training by Hack, V, Weiss, C, Friedmann, B, Suttner, S, Schykowski, M, Erbe, N, Benner, A, Bärtsch, P, Dröge, W

“…The purpose of the present study was to investigate the role of plasma amino acids and glutathione (GSH) on the absolute number of leukocyte and lymphocyte…”
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Role of cysteine and glutathione in HIV infection and cancer cachexia: therapeutic intervention with N-acetylcysteine by Dröge, W, Gross, A, Hack, V, Kinscherf, R, Schykowski, M, Bockstette, M, Mihm, S, Galter, D

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Decrease in phosphocreatine level in skeletal muscle of SIV-infected rhesus macaques correlates with decrease in intracellular glutathione by Hack, V, Gross, A, Böhme, A, Stahl-Hennig, C, Dröge, W

“…Loss of skeletal muscle tissue (cachexia) is one of the hallmarks of HIV infection. It has been found (1) that creatine kinase, i.e., an enzyme of pivotal…”
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Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1 /Fas) Mediated apoptosis by Strand, Susanne, Hofmann, Walter J, Grambihler, Annette, Hug, Hubert, Volkmann, Martin, Otto, Gerd, Wesch, Horst, Mariani, Sara M, Hack, Volker, Stremmel, Wolfgang, Krammer, Peter H, Galle, Peter R

“…Wilson's disease can result in fulminant liver failure due to hepatic copper overload. The CD95 system mediates apoptosis and has been demonstrated to be…”
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Reactive Oxygen Intermediates Are Involved in the Induction of CD95 Ligand mRNA Expression by Cytostatic Drugs in Hepatoma Cells by Hug, Hubert, Strand, Susanne, Grambihler, Annette, Galle, Jan, Hack, Volker, Stremmel, Wolfgang, Krammer, Peter H., Galle, Peter R.

“…Oxidative stress has been associated with the induction of programmed cell death. The CD95 ligand/receptor system is a specific mediator of apoptosis. We have…”
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Improvement of immune functions in HIV infection by sulfur supplementation : Two randomized trials by BREITKREUTZ, R, PITTACK, N, NEBE, C. T, SCHUSTER, D, BRUST, J, BEICHERT, M, HACK, V, DANIEL, V, EDLER, L, DRÖGE, W

“…To determine the therapeutic effect of sulfur amino acid supplementation in HIV infection we randomized 40 patients with antiretroviral therapy (ART; study 1)…”
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Differential reconstitution of mitochondrial respiratory chain activity and plasma redox state by cysteine and ornithine in a model of cancer cachexia by USHMOROV, A, HACK, V, DRÖGE, W

“…The mechanism of wasting, as it occurs in malignant diseases and various etiologically unrelated conditions, is still poorly understood. We have, therefore,…”
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The redox state as a correlate of senescence and wasting and as a target for therapeutic intervention by HACK, V, BREITKREUTZ, R, KINSCHERF, R, RÖHRER, H, BÄRTSCH, P, TAUT, F, BENNER, A, DRÖGE, W

“…The loss of body cell mass (bcm) in senescence and wasting is poorly understood. We now show that the plasma cystine/acid soluble thiol ratio, ie, an indicator…”
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Rear view projection can set the stage for learning by HACK, V I

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How to Expedite Learning through Color by HACK, VINCENT I

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Abnormal glutathione and sulfate levels after interleukin 6 treatment and in tumor-induced cachexia by Hack, V, Gross, A, Kinscherf, R, Bockstette, M, Fiers, W, Berke, G, Dröge, W

“…Excessive urea excretion associated with a negative nitrogen balance and massive loss of skeletal muscle mass (cachexia) is a frequent life threatening…”
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Cystine levels, cystine flux, and protein catabolism in cancer cachexia, HIV/SIV infection, and senescence by Hack, Volker, Schmid, Dietmar, Breitkreutz, Raoul, Stahl‐Henning, Christiane, Brings, Peter, Kinscherf, Ralf, Taut, Friedemann, Holm, Eggert, Dröge, Wulf

“…Patients with skeletal muscle catab‐olism (cachexia) fail to conserve the skeletal muscle protein and release large amounts of nitrogen as urea. Previous…”
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