Search Results - "Hack, Carolin C."
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The contributions of breast density and common genetic variation to breast cancer risk
Published in JNCI : Journal of the National Cancer Institute (01-05-2015)“…We evaluated whether a 76-locus polygenic risk score (PRS) and Breast Imaging Reporting and Data System (BI-RADS) breast density were independent risk factors…”
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Collective forces of tumor spheroids in three-dimensional biopolymer networks
Published in eLife (30-04-2020)“…We describe a method for quantifying the contractile forces that tumor spheroids collectively exert on highly nonlinear three-dimensional collagen networks…”
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Evaluation of automated techniques for extraction of circulating cell-free DNA for implementation in standardized high-throughput workflows
Published in Scientific reports (07-01-2023)“…Analysis of circulating cell-free DNA (ccfDNA) is a suitable tool for detecting somatic mutations for the purpose of making decisions on treatment, monitoring…”
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Ex Vivo Chromosomal Radiosensitivity Testing in Patients with Pathological Germline Variants in Breast Cancer High-Susceptibility Genes BReast CAncer 1 and BReast CAncer 2
Published in Current issues in molecular biology (10-08-2023)“…Background: Individual radiosensitivity is an important factor in the occurrence of undesirable consequences of radiotherapy. The potential for increased…”
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Mammographic density and prognosis in primary breast cancer patients
Published in Breast (Edinburgh) (01-10-2021)“…Mammographic density (MD) is one of the strongest risk factors for breast cancer (BC). However, the influence of MD on the BC prognosis is unclear. The…”
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Unbiased high-dimensional flow cytometry identified NK and DC immune cell signature in Luminal A-type and triple negative breast cancer
Published in Oncoimmunology (2024)“…Breast cancer is the most common malignancy in women worldwide and a highly heterogeneous disease. Four different subtypes are described that differ in the…”
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Predicting mammographic density with linear ultrasound transducers
Published in European journal of medical research (28-09-2023)“…Background High mammographic density (MD) is a risk factor for the development of breast cancer (BC). Changes in MD are influenced by multiple factors such as…”
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Low-Risk Women with Suspicious Microcalcifications in Mammography-Can an Additional Breast MRI Reduce the Biopsy Rate?
Published in Diagnostics (Basel) (01-03-2023)“…In the German Mammography Screening Program, 62% of ductal carcinoma in situ (DCIS) and 38% of invasive breast cancers are associated with microcalcifications…”
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Cell-In-Cell Structures in Early Breast Cancer Are Prognostically Valuable
Published in Cells (Basel, Switzerland) (24-12-2022)“…Cell-in-cell (CIC) structures in breast cancer have so far been studied in a small inhomogeneous patient population, suggesting the prognostic importance of…”
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Active Participation, Mind–Body Stabilization, and Coping Strategies with Integrative Medicine in Breast Cancer Patients
Published in Integrative cancer therapies (2021)“…Purpose: Increasing numbers of breast cancer survivors have led to a growing demand for integrative medicine. When patients have completed treatments…”
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Is Reduction Mammoplasty Cost-Effective? A Cost-Utility Analysis of Surgical Treatment for Macromastia in Germany
Published in Breast care (Basel, Switzerland) (01-12-2021)“…Background/Aims: Macromastia can cause physical and psychological problems. Conservative treatments such as physiotherapy and painkillers lead to substantial…”
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Analysis of Oncological Second Opinions in a Certified University Breast and Gynecological Cancer Center Regarding Consensus between the First and Second Opinion and Conformity with the Guidelines
Published in Breast care (Basel, Switzerland) (01-06-2021)“…Introduction: Oncological second opinions are becoming increasingly important in the era of complex treatments and established certified cancer centers…”
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Self-reported Improvement in Side Effects and Quality of Life With Integrative Medicine in Breast Cancer Patients
Published in Integrative cancer therapies (01-09-2018)“…Purpose. Although the demand from patients for integrative medicine is increasing, complementary medicine services are still quite heterogeneous and have not…”
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Influence of Family History of Breast or Ovarian Cancer on Pathological Complete Response and Long-Term Prognosis in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy
Published in Breast care (Basel, Switzerland) (01-06-2021)“…Purpose: In breast cancer, a pathological complete response (pCR) has been described as generally resulting in a favorable prognosis. However, there are…”
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Using automated texture features to determine the probability for masking of a tumor on mammography, but not ultrasound
Published in European journal of medical research (30-08-2017)“…Tumors in radiologically dense breast were overlooked on mammograms more often than tumors in low-density breasts. A fast reproducible and automated method of…”
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Impact of CCND1 amplification on the prognosis of hormone receptor–positive, HER2-negative breast cancer patients—correlation of clinical and pathological markers
Published in Breast cancer research and treatment (26-11-2024)“…The cyclin D1 gene (CCND1) encodes a key cell-cycle regulatory protein. Resistance to endocrine therapy is reportedly observed more often in patients with…”
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Pembrolizumab in combination with nab-paclitaxel for the treatment of patients with early-stage triple-negative breast cancer – A single-arm phase II trial (NeoImmunoboost, AGO-B-041)
Published in European journal of cancer (1990) (01-05-2023)“…Pembrolizumab is approved for the neoadjuvant/adjuvant treatment of early triple-negative breast cancer (TNBC) patients in combination with chemotherapy. The…”
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The Influence of Physical Training on Breast Cancer: The Role of Exercise-Induced Myokines in Regulating Breast Cancer Cell Growth and Survival
Published in International journal of molecular sciences (01-11-2024)“…The beneficial impact of physical training in lowering cancer risk is well known. However, the precise mechanisms linking physical training and cancer are not…”
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Complementary and alternative medicine (CAM) in women with endometriosis
Published in European journal of obstetrics & gynecology and reproductive biology (01-07-2021)“…•Endometriosis is highly debilitating for women affected.•CAM therapy methods might be good options in case conventional therapies fail.•Not enough research in…”
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Evaluation of a Wireless Localization System for Nonpalpable Breast Lesions — Feasibility and Cost-effectiveness in Everyday Clinical Routine
Published in In vivo (Athens) (01-09-2022)“…BACKGROUND/AIMSmaller, earlier-stage breast tumors are being found in breast cancer screening, and neoadjuvant chemotherapy is the gold standard when…”
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