Search Results - "Haciefendi, Ayten"

Mechanisms of abemaciclib, a CDK4/6 inhibitor, induced apoptotic cell death in prostate cancer cells in vitro by Guney Eskiler, Gamze, Deveci Ozkan, Asuman, Haciefendi, Ayten, Bilir, Cemil

“…•ABE treatment may be a promising treatment strategy in especially mCRPC.•ABE treatment significantly inhibited PC cell growth through apoptosis,…”
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Novel combination treatment of CDK 4/6 inhibitors with PARP inhibitors in triple negative breast cancer cells by Guney Eskiler, Gamze, Ozman, Zeynep, Haciefendi, Ayten, Cansaran-Duman, Demet

“…Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors provide promising results for treating hormone receptor-positive breast cancer. However, the efficacy of CDK4/6…”
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The suppression of ATR/Chk1 pathway by Elimusertib ATR inhibitor in triple negative breast cancer cells by Haciefendi, Ayten, Guney Eskiler, Gamze

“…Genomic instability in cancer cells is based on the aberrant activation of deoxyribonucleic acid (DNA) damage response and repair mechanisms. Targeting Ataxia…”
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The ATR inhibition by Elimusertib enhances the radiosensitivity of MDA-MB-231 triple negative breast cancer in vitro by Guney Eskiler, Gamze, Halis, Hatice, Hamarat, Kaan Furkan, Derlioglu, Rabia Rana, Ugurlu, Berat Tugrul, Haciefendi, Ayten

“…DNA damage response (DDR) is the principal mechanism regulating genomic stability and cell cycle checkpoint activation by coordinating DNA repair and apoptotic…”
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The prognostic and predictive values of differential expression of exosomal receptor tyrosine kinases and associated with the PI3K/AKT/mTOR signaling in breast cancer patients undergoing neoadjuvant chemotherapy by Guney Eskiler, Gamze, Kazan, Nur, Haciefendi, Ayten, Deveci Ozkan, Asuman, Ozdemir, Kayhan, Ozen, Mirac, Kocer, Havva Belma, Yilmaz, Fahri, Kaleli, Suleyman, Sahin, Elvan, Bilir, Cemil

“…Purpose Cancer cell-derived exosomes are the mediator of the tumor microenvironment and the molecular content of exosomes presents a promising prognostic or…”
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