Search Results - "Hachiya, Iwao"

Chemoselective reductions and iodinations using titanium tetraiodide by Hachiya, Iwao, Shimizu, Makoto

“…Titanium(IV) halides are extensively used in carboncarbon bond forming reactions as a Lewis acid and low valent titanium halides promote reductive coupling…”
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Synthesis of 3,6‐Disubstituted 4‐Ethoxycarbonylpyranoindol‐1‐ones Utilizing 3‐Amino‐2‐pyrone Synthesis by Fukuoka, Kota, Imai, Katsutoshi, Hirano, Kotaro, Goto, Shinsuke, Miura, Ryoya, Hachiya, Iwao

“…Synthesis of 3,6‐disubstituted 4‐ethoxycarbonylpyranoindol‐1‐ones is developed using palladium‐catalyzed intramolecular amination of…”
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Synthesis of 2,3-Disubstituted 4‑Ethoxycarbonyl-β-carbolin-1-ones: Application to the Synthesis of SL651498 and Its Analogue by Miura, Ryoya, Goto, Shinsuke, Hashimoto, Takahide, Hachiya, Iwao

“…Synthesis of 2,3-disubstituted 4-ethoxycarbonyl-β-carbolin-1-ones is developed using palladium-catalyzed intramolecular amination of…”
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Titanium Tetraiodide/Trimethylsilyl Iodide Synergistically Induced Cyclization of N‑(2-Cyanophenyl)benzamides into 2‑Aryl-4-iodoquinazolines by Hachiya, Iwao, Nagoshi, Shintaro, Shimizu, Makoto

“…Synthesis of 2-aryl-4-iodoquinazolines is developed using titanium tetraiodide/trimethylsilyl iodide synergistically induced cyclization of…”
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2-Aryl-4-quinolone Synthesis Using the Thermal Rearrangement of Iminocyclobutenones by Shimizu, Makoto, Hachiya, Iwao, Yokoyama, Keiichi, Ito, Akinori

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Reductive aminopropylation of ketene silyl (thio)acetals leading to the synthesis of δ-amino esters by Mizota, Isao, Agatani, Shun, Hachiya, Iwao, Shimizu, Makoto

“…In the presence of silica gel or titanium tetrachloride, ketene silyl acetals or ketene silyl thioacetals underwent 1,4-addition with α,β unsaturated aldimines…”
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Use of N-Allylidene-1,1-diphenylethanamine as a Latent Acrolein Synthon in the Double Nucleophilic Addition Reaction of Ketene Silyl (Thio)acetals and Allylborolanes by Shimizu, Makoto, Kawanishi, Mami, Mizota, Isao, Hachiya, Iwao

“…In the presence of silica gel and water, a mixture of ketene silyl acetals and 2-allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane underwent 1,4- and subsequently…”
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Synthesis of Multi-Substituted 2-Iminopyridine by Conjugate Addition of Ethyl Cyanoacetate Derivatives to Alkynyl Imines by Hachiya, Iwao, Minami, Yushi, Aramaki, Tetsuya, Shimizu, Makoto

“…The synthesis of multi‐substituted 2‐iminopyridines by conjugate addition of ethyl cyanoacetate derivatives to alkynyl imines has been developed. The reaction…”
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N‐Allylideneamines Derived from Acrolein: Synthesis and Use as Acceptors of Two Nucleophiles by Mizota, Isao, Matsuda, Yuri, Hachiya, Iwao, Shimizu, Makoto

“…Two practical methods have been developed for the preparation of N‐allylideneamines 1b,c. One involves the isomerization of propargylamines and the other the…”
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Reductive Aldol and Mannich-Type Reactions of Azetidin-3-ones Promoted by Titanium Tetraiodide by Hata, Shingo, Fukuda, Daisuke, Hachiya, Iwao, Shimizu, Makoto

“…A good promoter: A convenient method is described for the generation and reaction of the enolates of aminoacetone equivalents, which uses the reduction of…”
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Regioselective Ring-Opening Reaction of 2-Mono-Substituted Azetidin-3-ones Promoted by the Combined Use of Titanium Tetraiodide and Its Chloro or Bromo Counterpart by Shimizu, Makoto, Hata, Shingo, Fukuda, Daisuke, Hachiya, Iwao

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Titanium Tetraiodide-Mediated Organic Reactions by Haneishi, Tsuyoshi, Hachiya, Iwao, Shimizu, Makoto

“…A variety of organic transformations using titanium tetraiodide are described, in which iodotitanation, reduction, and use as a Lewis acid are discussed in…”
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Two-Step Synthesis of 3,4-Ethylenedioxythiophene (EDOT) from 2,3-Butanedione by Shimizu, Makoto, Hachiya, Iwao, Yamamoto, Toshihiro, Inagaki, Tatsuhiko, Matsumoto, Tomohiro, Takahashi, Atsushi, Mizota, Isao

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Synthesis of 3,4-Ethylenedioxythiophene (EDOT) from (Z)-But-2-ene-1,4-diol or But-2-yne-1,4-diol by Shimizu, Makoto, Hachiya, Iwao, Matsumoto, Tomohiro, Inagaki, Tatsuhiko, Takahashi, Atsushi

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Aza-Prins Reaction Promoted by Titanium Tetraiodide and Iodine by Shimizu, Makoto, Baba, Toru, Toudou, Shingo, Hachiya, Iwao

“…In the presence of titanium tetraiodide and iodine, olefins and acetylenes underwent aza-Prins reaction to give 1,3-iodoamines in good yields…”
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Novel 2-Pyridone Synthesis via Nucleophilic Addition of Malonic Esters to Alkynyl Imines by Hachiya, Iwao, Ogura, Kana, Shimizu, Makoto

“…A novel 2-pyridone synthesis via nucleophilic addition of malonic esters to alkynyl imines has been developed. The reaction of dialkylalkyl sodiomalonates with…”
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3-Iodo-3-trimethylsilylpropenal as a Useful Unit for Pinacol Coupling and Subsequent Functional Group Transformations by Shimizu, Makoto, Okimura, Hisashi, Manabe, Nobuyuki, Hachiya, Iwao

“…Titanium tetraiodidesilyl-mediated pinacol coupling reaction of (Z)-3-iodo-3-trimethylsilylpropenal is used for the preparation of…”
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Trichlorosilane-Dimethylformamide (Cl3SiH-DMF) as an Efficient Reducing Agent. Reduction of Aldehydes and Imines and Reductive Amination of Aldehydes under Mild Conditions Using Hypervalent Hydridosilicates by Kobayashi, Shu, Yasuda, Masaru, Hachiya, Iwao

“…Trichlorosilane-dimethylformamide (Cl3SiH-DMF) was found to be an effective reducing agent for reduction of aldehydes to alcohols, imines to amines, and also…”
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Synthesis of 2-Aminopyridinium Salts from 2-Iminopyridines as a Starting Material by Shimizu, Makoto, Hachiya, Iwao, Fukutomi, Makoto, Kugisaki, Naoki, Shimada, Satoshi

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3,4,5,6-Tetrasubstituted 2-Pyridone Synthesis via Nucleophilic Addition of Active Methine Compounds to Dialkynyl Imines Directed to the Synthesis of (-)-A58365A by Shimizu, Makoto, Hachiya, Iwao, Fukushima, Shiho

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