Search Results - "Habotta, Ola A."
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Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways
Published in Mediators of inflammation (2020)“…Berberine (BER), a natural isoquinoline alkaloid, has been demonstrated to have appreciable anticolitis effects. Nevertheless, the protective mechanism of BER…”
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2
Hepatorenal protective efficacy of flavonoids from Ocimum basilicum extract in diabetic albino rats: A focus on hypoglycemic, antioxidant, anti-inflammatory and anti-apoptotic activities
Published in Biomedicine & pharmacotherapy (01-12-2021)“…Plant derived phytochemical therapy is a bright candidate for treatment of diabetes and its associated complications. Ocimum baslicum is used as an…”
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3
The potential antioxidant bioactivity of date palm fruit against gentamicin-mediated hepato-renal injury in male albino rats
Published in Biomedicine & pharmacotherapy (01-11-2021)“…Gentamicin (GM) is a commonly prescribed antimicrobial drug used for treatment of infections but associated hepatic and renal complications restrict its…”
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4
Sesquiterpene nootkatone counteracted the melamine-induced neurotoxicity via repressing of oxidative stress, inflammatory, and apoptotic trajectories
Published in Biomedicine & pharmacotherapy (01-09-2023)“…Melamine (ML), a chemical substance of high nitrogen content, is used as a food adulterant. Former evidences implied that ML could induce a variety of toxic…”
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5
Biochemical and histopathological effects of copper oxide nanoparticles exposure on the bivalve Chambardia rubens (Lamarck, 1819)
Published in Bioscience reports (01-05-2023)“…Copper nanoparticles are widely incorporated into many applications, including air and liquid filters, wood preservatives, batteries, thermal and electrical…”
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6
Resistomycin Suppresses Prostate Cancer Cell Growth by Instigating Oxidative Stress, Mitochondrial Apoptosis, and Cell Cycle Arrest
Published in Molecules (Basel, Switzerland) (30-11-2023)“…Globally, prostate cancer is among the most threatening and leading causes of death in men. This study, therefore, aimed to search for an ideal antitumor…”
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7
Selenium-enriched yeast modulates the metal bioaccumulation, oxidant status, and inflammation in copper-stressed broiler chickens
Published in Frontiers in pharmacology (14-10-2022)“…Copper (Cu) could be seriously hazardous when present at excessive levels, despite its vital contribution to various cellular processes. Selenium-enriched…”
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Therapeutic activity of green synthesized selenium nanoparticles from turmeric against cisplatin-induced oxido-inflammatory stress and cell death in mice kidney
Published in Bioscience reports (30-11-2023)“…Cisplatin (CDDP) is a commonly prescribed chemotherapeutic agent; however, its associated nephrotoxicity limits its clinical efficacy and sometimes requires…”
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9
Antiulcer activity of proanthocyanidins is mediated via suppression of oxidative, inflammatory, and apoptotic machineries
Published in Journal of food biochemistry (01-02-2022)“…Gastric ulcer (GU) is a lesion in the gastric mucosa associated with excessive oxidative damage, inflammatory response, apoptotic events, and irritation which…”
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10
Differential cellular localization of lectins in the testes of dromedary camel (Camelus dromedarius) during active and inactive breeding seasons
Published in BMC veterinary research (04-11-2023)“…Abstract The reproductive activity of the male dromedary camel ( Camelus dromedarius ) as a seasonal breeder is affected by various seasonal changes that…”
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11
Alchemilla vulgaris modulates isoproterenol-induced cardiotoxicity: interplay of oxidative stress, inflammation, autophagy, and apoptosis
Published in Frontiers in pharmacology (07-08-2024)“…Isoproterenol (ISO) is regarded as an adrenergic non-selective β agonist. It regulates myocardial contractility and may cause damage to cardiac tissues…”
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Comparative neuroprotective effects of Cerebrolysin, dexamethasone, and ascorbic acid on sciatic nerve injury model: Behavioral and histopathological study
Published in Frontiers in neuroanatomy (01-02-2023)“…The majority of the suggested experimental modalities for peripheral nerve injury (PNI) result in varying degrees of recovery in animal models; however, there…”
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The Potential Therapeutic Role of Green-Synthesized Selenium Nanoparticles Using Carvacrol in Human Breast Cancer MCF-7 Cells
Published in Applied sciences (01-06-2023)“…The disadvantages and side effects of currently available breast cancer (BC) therapies have compelled researchers to seek new therapeutic strategies. This…”
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14
Therapeutic role of mesenchymal stem cells and platelet-rich plasma on skin burn healing and rejuvenation: A focus on scar regulation, oxido-inflammatory stress and apoptotic mechanisms
Published in Heliyon (01-09-2023)“…Cell-based therapies have great promise in accelerating and improving burn wound healing. It is a growing need to scale their competence to meet the clinical…”
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15
Suppression of NLRP3 inflammasome orchestrates the protective efficacy of tiron against isoprenaline-induced myocardial injury
Published in Frontiers in pharmacology (15-08-2024)“…The major contribution of myocardial damage to global mortalities raises debate regarding the exploration of new therapeutic strategies for its treatment…”
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16
Possibility of using fatty acid profiles for the authentication of beef adulterated with pork, donkey, and dog meat
Published in Italian journal of food science (01-04-2024)“…Detection of meat adulteration is a critical issue in food labeling procedures and a serious concern related to food fraud, authenticity, and religious…”
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Phytic acid attenuates acetaminophen-induced hepatotoxicity via modulating iron-mediated oxidative stress and SIRT-1 expression in mice
Published in Frontiers in pharmacology (01-05-2024)“…Administration of high doses of acetaminophen (APAP) results in liver injury. Oxidative stress and iron overload play roles in the pathogenesis of APAP-induced…”
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Therapeutic effects of intermittent fasting on high-fat, high-fructose diet; involvement of jejunal aquaporin 1, 3, and 7
Published in Heliyon (15-04-2024)“…Aquaporins (AQPs) are transmembrane channel proteins. Aquaporin 1 (AQP1), Aquaporin 3 (AQP3), and Aquaporin 7 (AQP7) are expressed in the jejunum. The purpose…”
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Biosynthesized Selenium Nanoparticles Using Epigallocatechin Gallate Protect against Pentylenetetrazole-Induced Acute Epileptic Seizures in Mice via Antioxidative, Anti-Inflammatory, and Anti-Apoptotic Activities
Published in Biomedicines (01-07-2023)“…Several negative outcomes are associated with current anti-epileptic medications. Epigallocatechin gallate (EGCG) is a plant-derived compound called catechin…”
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Pergularia tomentosa coupled with selenium nanoparticles salvaged lead acetate-induced redox imbalance, inflammation, apoptosis, and disruption of neurotransmission in rats’ brain
Published in Open Chemistry (23-11-2022)“…In this study, the neuroprotective potential of either leaf methanolic extract (PtE) alone or in combination with selenium nanoparticles (SeNPs-PtE) was…”
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